High-throughput dynamic and static light scattering (DLS/SLS) measurements using commercially available microplates - Reducing time and running costs.
The DynaPro Plate Reader 3 is a commercially available microplate that is a light scattering measurement device capable of measuring the size, molecular weight, concentration, and interactions of proteins, nanoparticles, and other polymers. This plate-based device allows for very high-throughput measurements compared to traditional cuvette-based light scattering devices. Additionally, after dispensing into the plate, there is no need to touch the liquid, minimizing sample carryover. 【Features】 - Compatible with commercially available microplates - Supports high-throughput measurement of multiple samples and automation - Simultaneous measurement of dynamic light scattering (DLS) and static light scattering (SLS) - Saves time and running costs - Non-destructive measurement allows the measured plates to be repurposed for other analytical devices
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basic information
A dynamic and static light scattering measurement device that demonstrates its power in high-throughput screening of biopharmaceuticals such as monoclonal antibodies and virus-like particles (VLP), LNPs (lipid nanoparticles) and metal nanoparticles, as well as viral and non-viral gene vectors, can perform the following measurements: - Particle size (Rh) and size distribution - Molecular weight (Mw) - Aggregate and stability parameters (Tm, Tagg, kD, A2) - Purity, turbidity
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Applications/Examples of results
Stability testing of biopharmaceuticals (evaluation of thermal denaturation and colloidal stability) Measurement of nanoparticle size distribution Evaluation of aggregation or oligomerization Measurement of solution viscosity
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Company information
Waters Corporation, headquartered in Milford, Massachusetts, USA, has played a pioneering role as a specialized manufacturer of liquid chromatography since its establishment in 1958. Actively engaged in the development of new products and technologies, it has grown into an international group company that supplies not only high-performance liquid chromatography but also mass spectrometers (MS) and thermal analysis instruments. Waters Japan started operations in 1973 (Showa 48) as the Japanese base of Waters Corporation. Inheriting the corporate ethos of the U.S. headquarters, we have made "Customer Success" our mission and continue to provide innovative technologies and lab solutions.