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  6. [Analysis Case] Evaluation of Component Distribution in Skin Cross-Section

[Analysis Case] Evaluation of Component Distribution in Skin Cross-Section

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last updated:Oct 03, 2025

一般財団法人材料科学技術振興財団 MST
一般財団法人材料科学技術振興財団 MST
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It is possible to visualize molecular information of organic and inorganic substances.

We created skin tissue samples and evaluated the distribution of biogenic components in freeze-dried samples using TOF-SIMS. Since TOF-SIMS identifies components based on the mass of molecular ions, it does not require labels such as fluorescent substances, allowing for the evaluation of distribution without the influence of labeled materials. The mapping results confirmed that arginine, a natural moisturizing factor (NMF), and cholesterol, which retains moisture as an intercellular lipid, are localized in the stratum corneum. This method is also effective for assessing the permeation state during drug application.

    Contract measurement
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[Analysis Case] Evaluation of Component Distribution in Skin Cross-Section

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Measurement method: TOF-SIMS Product fields: Cosmetics, pharmaceuticals, daily necessities, biotechnology Analysis purpose: Composition distribution evaluation

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Analysis of cosmetics, pharmaceuticals, daily necessities, and biotechnology.

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一般財団法人材料科学技術振興財団 MST

一般財団法人材料科学技術振興財団 MST

Testing, Analysis and Measurement

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MST is a foundation that provides contract analysis services. We possess various analytical instruments such as TEM, SIMS, and XRD to meet your analysis needs. Our knowledgeable sales representatives will propose appropriate analysis plans. We are also available for consultations at your company, of course. We have obtained ISO 9001 and ISO 27001 certifications. Please feel free to consult us for product development, identifying causes of defects, and patent investigations! MST will guide you to solutions for your "troubles"!

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