New security in life brought by electronic olfaction.
Monozukuri (Saitama University Research Seed Collection 2025-27 p.49)
Keywords: electrochemical sensors, two-dimensional chemical imaging sensors, microarrays, electronic nose, molecular recognition
There are often discussions about losing the ability to smell or taste due to the new coronavirus, but even though we usually do not pay much attention to our sense of smell, it provides us with a remarkably diverse range of information in our surroundings, not just related to food and drink. For example, the first indication of a fire in an unseen location or a malfunctioning device can often come from smell. Additionally, dogs with keen olfactory senses are active as detection dogs in airports and police work, and research is being conducted to diagnose diseases based on the odors present in the breath of sick individuals. While it is challenging to develop technology that can match a dog's sense of smell for everyday use, we have developed a new two-dimensional electrochemical sensor and built a system that utilizes a large number of sensors simultaneously. Ordinary sensors increase sensitivity by enhancing their ability to capture odors, but we aim to achieve high-sensitivity electronic noses from a new perspective: even if a sensor captures an odor, it releases it so that the next sensor in line can capture it and produce a signal, repeating this process.
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Hidekazu Uchida, Professor Graduate School of Science and Engineering, Department of Mathematical and Electronic Information, Field of Electrical and Electronic Physics 【Recent Research Themes】 ● High-sensitivity enzyme sensors for disease diagnosis through breath measurement ● Highly reliable gas sensors for early fire detection ● Chemical image sensors using new technology (Light Addressable Amperometric Sensor) ● High-sensitivity odor discrimination sensors comparable to those of dogs
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【Appeal Points to the Industry】 ● The mechanism of detecting molecules by combining numerous sensors like the tongue and nose is made possible by the functionality of two-dimensional electrochemical sensors. This is the world's first technology that has broadened its application range by shifting from voltage measurement to current measurement. ● Additionally, it is highly compatible with microarray systems, making it a suitable measurement technology for building drug discovery screening systems. 【Examples of Practical Use, Applications, and Utilization】 ● Visualization of transient phenomena through chemical image sensing ● A new type of microarray system for drug discovery screening
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Overview of Two-Dimensional Electrochemical Sensors
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The Saitama University Open Innovation Center is a center that functions as a liaison office for industry-academia-government collaboration. It consists of three departments: the Industry-Academia-Government Collaboration Department, the Intellectual Property Department, and the Startup Support Department, each staffed with coordinators well-versed in various fields. The center's activities include solving technical challenges in companies, supporting the implementation of joint research, and conducting technology transfer aimed at introducing and utilizing Saitama University's intellectual property.