Simultaneous measurement of TOC and conductivity to analyze non-conductive organic substances in cleaning agents.
300_00027
[Application Note] A New Perspective on Cleaning Validation: Residual Assessment of Cleaning Agents through Simultaneous Measurement of TOC and Conductivity
In the pharmaceutical industry, cleaning validation of manufacturing equipment is a crucial element of quality control. In cleaning validation, conductivity is useful for detecting residual cleaning agents, but it cannot accurately assess the concentration of organic substances. TOC is very useful in the cleaning evaluation of manufacturing equipment because it can detect both types of organic substances (conductive and non-conductive). Particularly in cases where non-conductive organic substances are present, relying solely on conductivity for cleaning evaluation increases the risk of missing organic contamination.
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This paper introduces a method for effectively analyzing non-conductive organic substances in cleaning agents by simultaneously measuring TOC and conductivity. For more details, please refer to the application note.
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Cleaning validation
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Since our establishment in 1967, we have been dedicated to the development and dissemination of water quality measurement devices that anyone can use quickly, easily, and with high precision. In today's world, where the effective use of water, a limited resource, is required alongside environmental conservation, we aim to be a total solution provider that responds to all water environments by utilizing our water quality measurement devices, technology, and services. Furthermore, leveraging the latest technology and years of know-how, we are committed to delivering user-friendly and reliable water quality measurement devices more affordably, quickly, and widely.