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Improvement of Bioprocess Performance with Correct Yeast Extract

Improvement of Bioprocess Performance with Correct Yeast Extract

Did you know that the combination/formulation of yeast extract may significantly affect fermentation conditions? 【*Test report available!】

Yeast extract," widely used in the fermentation industry, is aimed at enhancing the productivity and yield of microbial cultures. Yeast extract comes in various types, including amino acid-rich, nucleic acid-rich, and peptide-rich varieties. By reviewing the combinations and formulations of these yeast extracts, there is potential for improving fermentation and culture processes. This document presents test data related to the above. The yeast extract handled by Higuchi Shokai is manufactured by Ohly, a long-established yeast extract producer in Germany. It has a proven track record not only in lactic acid bacteria culture but also widely in the fermentation industry. Please take a look at our catalog if you are interested! *For more details, please refer to the PDF document or feel free to contact us.

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Cosmetic ingredient Circadian rhythm regulating ingredient CIRCALYS

Cosmetic ingredient Circadian rhythm regulating ingredient CIRCALYS

Circadian rhythm adjustment, skin stress relief, anti-fatigue, skin activation, anti-aging, improvement of dark circles, reduction of tear bags, wrinkle improvement, enhancement of radiance.

In the midst of rapid social development, our bodies are being attacked by various environmental and stress factors (night shifts, overtime, lack of sleep, etc.). This stress disrupts the body's natural rhythms (circadian rhythms). Skin homeostasis is also maintained by circadian rhythms, and disturbances in these rhythms can lead to a decline in skin health and beauty (symptoms of fatigue appearing on the face: dark circles, bags under the eyes, fine lines, dull complexion, etc.). A decrease in perceived beauty may also lead to a reduction in mental health and feelings of happiness. SARCALIS helps regulate circadian rhythms and cares for skin, mind, and fatigue. In Vitro - Restores the expression levels of clock genes CLOCK, CRY1, and PER to youthful levels. - SIRT1 (anti-aging gene): +56% - KLOTHO (anti-aging gene): +33% - HIF-1α (maintenance of skin homeostasis): +89% - 8-OHdG (marker of DNA damage): -51% - Oxytocin levels: +31% (feelings of happiness) - Endocannabinoid levels: +68% (stress reduction) - Endorphin levels: +55% (good mood) and more. In Vivo - Size of bags under the eyes: -28% - Darkness of dark circles: -13% - Wrinkles under the eyes: -21% - Skin stress relief and more.

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Cosmetic ingredients UV, BL, IR protection plant extract Sorberlin

Cosmetic ingredients UV, BL, IR protection plant extract Sorberlin

UV, IR, BL protectors, Watafuji Utsugi flower extract, phenylpropanoids, containing verbascoside, containing echinacoside.

Exposure of the skin to UV, BL, and IR can lead to the formation of free radicals and inflammatory responses, resulting in apoptosis and the breakdown of the extracellular matrix (ECM). These can cause short-term issues such as sunburn, dryness, sensitive skin, and erythema, while long-term effects may include dark spots, uneven skin tone, and photoaging. Sorberlin focuses on the flowers of the Japanese bush clover, which are rich in phenylpropanoids that absorb UV, BL, and IR, particularly standardizing high contents of verbascoside and echinacoside, which have strong light-absorbing effects. - UV irradiation: Inhibition of lipid oxidation: 54% Inhibition of isomerization of urocanic acid: 70% Inhibition of apoptosis: 57% Inhibition of sunburn cells: 40% Inhibition of MMP-1: 30% Promotion of elastin production: 7% Inhibition of TNF-α: 36% Inhibition of melanin: 62% - BL irradiation: Inhibition of ROS production: 43% Inhibition of TGF-β1: 88% Promotion of decorin production: 29% Reduction of aging spots: 81% - Under IRA irradiation: Inhibition of MMP-1: 22% Inhibition of IL-6: 27% Inhibition of TGF-β1: 35% - In Vivo: Inhibition of erythema (L value): 33% ITA value: 189%

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Cosmetic ingredients Anti-pollution plant extract Arbolis

Cosmetic ingredients Anti-pollution plant extract Arbolis

Urban pollution, anti-pollution, detox function, antioxidant, anti-inflammatory, barrier function recovery, epidermal densification, barrier function recovery effect.

This product is an anti-pollution ingredient developed with a focus on the antioxidant and anti-inflammatory effects of plant-derived lignans and silymarin, which have been known for a long time. It protects the skin from damage caused by pollutants through four approaches: 1) Molecular level: Maintaining the redox balance of skin tissue and detoxification effects - Redox balance: Suppression of hydrogen peroxide and hydroperoxide by glutathione - Epidermal densification: Promotion of sebocyte differentiation and production of keratin structure proteins - Detoxification function: Conversion of harmful epoxides to dihydrodiols - Lipid oxidation suppression: Accumulation of iron 2) Cellular level: Prevention of cell damage - Promotion of DJ-1 CYTO: Suppression of inflammatory responses and oxidative stress 3) Skin tissue level: Strengthening barrier function - Promotion of the production of cornefin, occludin, and filaggrin: Densification of the epidermis (+63%) to protect against pollutants. 4) Organ level: Improvement of appearance through a holistic approach Moisture: +34% Radiance: +47% Whitening: +154% Suppression of pigmentation: +155%

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Cosmetic ingredients Zombie cells (aging cells) suppression anti-aging Heberis

Cosmetic ingredients Zombie cells (aging cells) suppression anti-aging Heberis

Ingredients suitable for positive aging care for the silver generation! Contains various active ingredients with zombie cell effects!

Since the population of the silver generation (aged 65 and over) surpassed that of the population aged 5 and under in 2020, the number of people in the silver generation has been increasing year by year. In particular, the proportion of women in the silver generation is expected to reach 13.4% by 2030. Modern silver generation women tend to prefer aging gracefully, and "Heberis" has been developed as an ingredient for positive aging. This product is a fermented extract from a bacterium called Sphingomonas, which can survive in extreme environments. It contains various active ingredients, including polar lipids, that have a zombie cell effect. ■In Vitro - Induction suppression of zombie cells: p21: -58%, p16: -20% - Suppression of zombie cells: -78% (β-galactosidase) - Suppression of SASP: IL-8: -32%, IL-6: -33% - Recovery of extracellular matrix: collagen production: +&%, fibrin: +22%, proteoglycan: +7% ■In Vivo - Depth of crow's feet wrinkles: -8% - Skin roughness: +14% - Elasticity: +12% - Tone (sensory evaluation): brightness: 74%, uniformity: 83% - Psychological aspect: self-esteem: +10.5%, mood state: +9%

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Cosmetic ingredient Slimming plant extract (Ivy Cosmelean)

Cosmetic ingredient Slimming plant extract (Ivy Cosmelean)

Improvement of dark circles under the eyes, removal of cellulite, soothing effect, promotion of blood circulation, Western ivy leaf/stem extract, hederacoside, skincare, body care.

Ivy Cosme Ren is an extract derived from the stems and leaves of ivy, containing: Hedera coside: 0.4-0.6%, Saponins: 2.5-6.0%, Flavonoid glycosides, Phenolic acids, and Polyacetylenes. Cosmetic ingredient name: Hedera helix leaf/stem extract <Mechanism of action> It exerts a drainage effect (blood flow promotion effect) through two pathways: (1) Microcirculation promotion effect due to relaxation (2) Adjustment of capillary permeability through anti-hyaluronidase effect <Efficacy> Removes cellulite and improves skin unevenness Reduces the appearance of dark circles under the eyes, providing a more relaxed expression In Vitro: Blood flow promotion effect in microvessels: +4% (3 hours after application), +14% (applied twice a day for 14 days)

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Cosmetic ingredients high-end beauty component truffle extract (heat shock protein)

Cosmetic ingredients high-end beauty component truffle extract (heat shock protein)

Heat shock protein, black diamond, truffle extract, antioxidant, protection, cell activation, anti-aging, high-end ingredients.

This product is an extract derived from the black truffle of the Tuber melanosporum species. Black truffles are known as a luxury ingredient. Their rich and robust aroma and delicate flavor are highly valued, earning them the nickname "black diamonds." Truffles produce a wide variety of compounds during their maturation period, with over 50 aroma-related compounds discovered and collected by animals and others. Due to their abundant active ingredients, truffles have been used in traditional medicine, and research is currently being conducted on their anti-cancer effects and treatment for Alzheimer's disease. <Active Ingredients> - Oligosaccharides, polysaccharides - Phenolic compounds - Phosphorus, potassium - Amino acids, proteins <Efficacy> Antioxidant effects (Villares et al., 2012): Inhibition of lipid oxidation Protection effects (Zampieri et al., 2011): Increased stimulation of various heat shock protein genes Moisturizing effects (Martini and Seiller, 2006): Cell activation effects (Martini and Seiller, 2006):

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Cosmetic ingredients, upcycled, plant-based scrub, plant extracts, GT Corporation.

Cosmetic ingredients, upcycled, plant-based scrub, plant extracts, GT Corporation.

This is a list of plant-based extracts and scrub products for upcycling from Green Tech Company.

- Argan oil cake (oil residue): Argania spinosa extract - Off-spec melon fruit: Melon fruit extract (moisturizing effect) - Off-spec lime fruit: Lime fruit extract - Off-spec cucumber fruit: Cucumber fruit extract - Beehive: Propolis extract - Byproduct of spice manufacturing: Saffron flower extract - Byproduct of olive oil production: Olive fruit extract - Byproduct of tea leaf screening: Tea leaf extract - Byproduct of baobab seed oil production (baobab pulp): Baobab pulp extract (moisturizing effect, lifting effect)

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Cosmetic ingredients - Premium beauty component caviar extract (moisturizing, antioxidant, regenerative material)

Cosmetic ingredients - Premium beauty component caviar extract (moisturizing, antioxidant, regenerative material)

Caviar extract, antioxidant, moisturizing, skin regeneration, anti-aging, amino acids, vitamins, calcium, magnesium.

Caviar is known as a luxury ingredient, and among them, the eggs of four types of sturgeon—Beluga, Osetra, Sevruga, and Sterlet—are said to produce the highest quality caviar. Caviar is known for its rich nutritional components, and its extract has efficacy in various cosmetics. <Ingredients (Gessener et al., 2002)> - Amino acids, proteins: Arginine, histamine, isoleucine, lysine, methionine - Vitamins: Vitamin C, B vitamins, etc. - Trace elements: Calcium, magnesium, phosphorus, potassium, sodium, etc. <Efficacy> - Moisturizing effect - Regenerative effect - Antioxidant effect

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Cosmetic Ingredients: New Generation Soft Peeling Flower Extract Flower Acid

Cosmetic Ingredients: New Generation Soft Peeling Flower Extract Flower Acid

A hibiscus flower extract with a high content of the new generation low-irritation peeling ingredient "keto acid." The peeling effect of keto acid promotes turnover.

AHA is known to be effective for peeling but also has irritant properties. GREENTECH discovered that the hibiscus flower containing Senegal acid has effects equivalent to AHA while having a higher content of keto acids, which are less irritating. Its extract, FLOWER ACIDS(R), possesses many efficacies, including peeling effects. = Efficacy = Promotes regeneration of epidermal cells Enhances moisture retention and smooths the skin's surface Low irritation compared to lactic acid Improves skin radiance and evenness Smooths wrinkles and fine lines When applied to hair, increases silkiness and shine. = Mechanism of Action = The high concentration of pyruvic acid (keto acid) contained in FLOWER ACIDS activates cell regeneration by reducing the aggregation of keratinocytes (dissolution of desmosomes) through conversion to lactic acid by epidermal dehydrogenase, thereby improving moisture retention in the upper layers of the epidermis. Pyruvic acid also stimulates the synthesis of collagen and mucopolysaccharides (Jaffary et al., 2016; Moy et al., 1996). = Efficacy = Promotes turnover: 12.5 days (Avg.) Moisturizing effect: +10%

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Cosmetic ingredient: Plankton extract with the power of gold.

Cosmetic ingredient: Plankton extract with the power of gold.

Golden Microalgae is an extract from plankton that accumulates gold biologically. It rejuvenates the skin, provides antioxidant, whitening, and calming effects through the power of gold.

Golden Alga (microalgae) is known for its heavy metal absorption properties. Greentech developed this product by focusing on the beauty effects of gold and the biological characteristics of this microalgae, based on 20 years of microalgae research. The extract made from algae cultured in a medium containing gold has gold included, which suppresses the irritant properties of gold while allowing only its effectiveness to be expressed. = Effectiveness = Golden Alga stimulates the production of specific important molecules related to regeneration, antioxidant effects, whitening, and soothing effects, such as hyaluronic acid, collagen, fibrillin-1 (elastin-like protein), major markers of inflammation, antioxidant response elements (ARE), and skin growth factors. = In Vitro = Filaggrin: +110% Heparin-binding EGF-like growth factor: +60% Glutaredoxin: +50% Heme oxygenase 1: +730% Superoxide dismutase 2: +280% Decorin: +110% Fibrillin 1: +150% Hyaluronan synthase 2: +70% Type 17 collagen: +200% AZGP1: +110% DKK-1: +70% and more.

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Beauty Supplement Ingredients Maritech Synergy High Purity Fucoidan + PPh

Beauty Supplement Ingredients Maritech Synergy High Purity Fucoidan + PPh

The ultimate ingredient that enhances beauty from within the body through the effects of high-purity fucoidan and polyphenols. It is high-purity fucoidan for inner beauty.

This product is a unique ingredient for supplements that beautify the complexion from within the body. It is a powdered product extracted and refined from Hijiki, which is rich in polyphenols and fucoidan, combining the powerful bioactivity derived from fucoidan and the strong antioxidant properties derived from polyphenols. <Anti-inflammatory Effects> • Suppression of IL-6 • Inhibition of COX-1, COX-2, and LOX 152 activity • Significant reduction of inflammation in the colon during acute colitis among others <Aging Suppression> Sirtuin 1 (SIRT1): +32.4% <Tissue Integrity> Up to 99% inhibition of elastase, collagenase, and tyrosinase activity <Antioxidant Capacity> ORAC 6.0: 28,689 μmol TE/g <Immune Function> Maritech(R) Synergy may induce immune modulation effects, support immune function, and promote healthy, radiant skin.

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Cosmetic ingredient, tea leaf extract with lipid peroxidation prevention effect, TEALINE.

Cosmetic ingredient, tea leaf extract with lipid peroxidation prevention effect, TEALINE.

This is an extract from three types of anti-tea leaves (green tea, white tea, and red tea) that protects at the molecular and cellular level from oxidative stress through their antioxidant power.

This is an extract derived from three types of leaves: green tea, white tea, and red tea. This product contains an extract that suppresses damage caused by external oxidation and helps to reduce wrinkles and spots, thanks to the antioxidant power of the three types of black tea leaves. <Source Ingredients> - Green Tea: Rich in epigallocatechin gallate (EGCG), a major type of catechin, which is a kind of polyphenol with antioxidant properties. - White Tea: A precious tea made from buds that were only used by Chinese emperors. It is rich in antioxidants such as epicatechin gallate, epigallocatechin (EPC), and catechins/epicatechins. - Red Tea (Rooibos Tea): Contains a wealth of polyphenols and flavonoids. <Efficacy Component Specification Values> Polyphenols: 60-90% Flavonoids: 1-5% <Effects> It suppresses oxidation reactions caused by free radicals and inhibits lipid peroxidation and MMP at the molecular and cellular levels. It protects tissues from external attacks such as light, pollution, and smoke. In vitro [Suppression of MDA production due to UVB irradiation] - Vitamin E: -46% - TEALINE 0.5%: -40%

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Cosmetics with over 100 active ingredients produced in 17 regions of France.

Cosmetics with over 100 active ingredients produced in 17 regions of France.

Introducing 16 data-rich products and over 100 types of extracts produced by Green Tech, a major French raw material manufacturer, sourced from France (17 regions).

Over 100 extracts and oil extracts from 17 regions of France Introduction of 16 data-rich raw materials BIOTILYS: Regulation of skin microbiota, protection booster, skin repair CARICILINE: Moisture content booster for the skin CERNILYS: Improvement of dark circles, brightness enhancement, care around the eyes EPICA: Extracellular matrix protection, improvement of crow's feet EPSILINE: Tanning agent, three types of natural protection HEBELYS: Improvement of skin and mood, anti-aging care for the silver generation HYDRALYS M: Hydration for dry skin, long-lasting moisture retention IAA 50: Slimming, fat breakdown LACTOPHYT: Long-lasting odor control, selective sterilization of odor-causing bacteria LIPACTIF CAMELINE: Nutritional supplementation for the skin, soft-touch oil MYRALYS: Rejuvenation around the eyes, eyelid lifting RAYOLYS: Booster for skin radiance and evenness REVERSKIN: Firming and regeneration booster for the skin SIDILINE: Redness improvement, blood vessel tightening, swelling reduction SILYPUR OC: Oral care, selective sterilization TILICINE: Moisture protection for fragile hair and scalp

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Plant-based estrogen (female hormone) extract for cosmetic ingredients for femcare.

Plant-based estrogen (female hormone) extract for cosmetic ingredients for femcare.

This is a soy-derived dry extract containing a high concentration of plant-based estrogens (daidzein, genistein, glycitein) for femcare.

This product is rich in isoflavones, such as daidzein, genistein, and glycitein, which have estrogen-like effects and are derived from dry extracts of soybeans. The estrogen levels in the body decrease due to aging and menopause. The decline in estrogen levels not only increases the risk of osteoporosis but also affects changes in the skin and appearance. <Efficacy of Soy Extract> Regeneration Promotion Effects - Promotion of type I and type III collagen production (genistein, glycitein) - Promotion of fibronectin production (glycitein) - Inhibition of elastase (glycitein) Photoprotection Effects - Inhibition of sunburn cells (UVB) Astringent Effects and more.

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