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HPLC Columns(hplc) - List of Manufacturers, Suppliers, Companies and Products

Last Updated: Aggregation Period:Dec 17, 2025~Jan 13, 2026
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HPLC Columns Product List

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"Cogent TYPE-C Silica" HPLC column

Unique "TYPE-C Silica" used in columns for Cogent HPLC manufactured by MicroSolv in the USA.

The "Cogent TYPE-C column," developed by MicroSolv in the United States, is a next-generation HPLC column based on high-purity Type-B silica that has been modified to replace over 95% of the silanol (Si-OH) on the silica surface with silane (Si-H). By replacing over 95% of the silanol with Si-H, a strong hydrophobic surface is created, providing greater stability compared to traditional silica-based phases. This means that end-capping is not necessary. 【Features】 ■ Usable in three modes in HPLC (RP (reverse phase), NP (normal phase), ANP (aqueous normal phase)) ■ High efficiency and high stability ■ Fast equilibration in gradient ■ Simultaneous separation of polar and non-polar compounds ■ Weak hydration shell *For more details, please refer to the catalog.

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ACE C18-AR HPLC Column

Mixed-mode HPLC column integrating C18 and phenyl groups.

This is an HPLC column manufactured by ACT in the UK, featuring a unique selectivity that integrates a phenyl group into a conventional C18 stationary phase. While it is a C18 phase, it exhibits selectivity for aromatic compounds like phenyl groups, providing complementary selectivity when sufficient separation cannot be achieved with C18 alone. **Features:** - A C18-phenyl integrated column that combines the advantages of both C18 phase and phenyl groups. - Utilizes ultra-high purity inert silica, demonstrating excellent peak shape and reproducibility. - Can be used with a water-rich mobile phase that enables retention and separation of polar substances. - Exhibits ultra-low bleed characteristics required for UV/LC-MS. - High-throughput column size.

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Inert LC Columns

Improve peak shape without using additives! Achieve high precision and throughput.

We would like to introduce our "Inert LC Column." We offer two products: Raptor Inert Biphenyl HPLC Columns and Raptor Inert ARC-18 HPLC Columns. There is no need for time-consuming conditioning or complex passivation. Additionally, the response and recovery rates of analytes are improved, lowering the detection limits. 【Four Benefits】 ■ Improved peak shape without using passivation or additives in the mobile phase ■ Enhanced response and recovery rates of analytes, resulting in lower detection limits ■ Minimization of variability in analytical results, achieving high precision and throughput ■ Elimination of the need for time-consuming conditioning and complex passivation *For more details, please refer to the PDF document or feel free to contact us.

  • Coating Agent

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mRNA analysis HPLC products RNASep series

Capable of handling everything from mRNA analysis to purification! RNASep series

The RNASep series from ADS Biotec in the United States is capable of handling everything from mRNA analysis to purification.

  • High Performance Liquid Chromatograph

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ACE C18-PFP HPLC column

HPLC column with pentafluorophenyl (PFP) group bonded to C18 phase.

This is an HPLC column developed by ACT in the UK, combining C18 with a PFP group. By integrating the PFP phase, which provides complementary selectivity to conventional C18, it improves the separation of polar basic substances and demonstrates selective characteristics for halogenated aromatic compounds and positional isomers. Additionally, the C18-PFP phase possesses multiple separation mechanisms (hydrophobic, π-π, hydrogen bonding, shape selectivity), showcasing its capabilities for mixtures that are difficult or impossible to separate with conventional C18. **Features** - A mixed column that combines C18 and PFP (PentaFluoroPhenyl) phases - Enhanced separation capability for polar basic substances - "Ultra-inert & Ultra-pure silica" essential for peak shape and reproducibility - Excellent stability for temperature programming analysis - Optimal for UV and LC/MS due to ultra-low bleed characteristics

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Reversed-phase HPLC column "Sunrise C18-SAC"

The reversed-phase HPLC column chemically modified with silanol groups is abbreviated as SAC, which stands for Silanol Activity Control.

The "Sunrise C18-SAC" is an HPLC column that intentionally does not use end-capping, utilizing the properties of residual silanol groups to bond C18. Thanks to silanol activity control technology, it achieves peaks of basic compounds without tailing, even without end-capping. The unique selectivity provided by the regulated silanol groups allows for separations that cannot be achieved with conventional C18 columns. [C18-SAC Octadecyl-SAC] ○ A "2nd Choice" column with effective residual silanol For more details, please contact us or download the catalog.

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ACE UltraCore UHPLC·HPLC Column

Solid core (core-shell) particles appear in the ACE column! Unique EBT technology achieves high stability across a wide pH range.

A new UltraCore column (HPLC/UHPLC column) has been added, featuring solid core (surface porous) particles from the UK ACE column group. Compared to conventional fully porous silica, it can be used at lower pressures, and due to the limited diffusion of analytes, it achieves high efficiency and sharp peak shapes. Additionally, it employs a unique encapsulation bonding technology (EBT) that delivers stable high performance across a wide pH range, dramatically increasing the ligand coverage on the silica surface and effectively eliminating the negative effects of unbound silanols. **Features** - Utilizes ultra-inert solid core particles (surface porous) - Monodisperse particle distribution combining low pressure and high efficiency - Expanded pH stability (1.5 to 11.0) - Compatible with LC/MS buffers - Employs unique encapsulation bonding technology (EBT)

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HPLC column "Supel Carbon LC"

Usable at 11,500 psi! Porous graphite carbon HPLC column

"Supel Carbon LC" is a porous graphite carbon HPLC column suitable for the separation of water-soluble analog compounds. The maximum operating temperature is 250°C, and it is compatible with pH 1 to 14. It is effective for the separation of hydrophilic analog compounds. Patented porous graphite carbon (PGC) particles are used as the packing material. 【Features】 ■ For the separation of water-soluble analog compounds ■ Can be backwashed ■ Compatible with pH 1 to 14 ■ Maximum operating temperature of 250°C ■ Usable at 11,500 psi (800 bar) *For more details, please refer to the PDF document or feel free to contact us.

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HPLC column "SunArmor"

Further evolution of surface treatment! HPLC columns that achieve astonishing alkali resistance.

"SunArmor" is an HPLC column that achieves remarkable alkali resistance while being silica gel particles, thanks to the newly developed silylation agent and TMS for final end-capping, in addition to the conventional Sunniest end-capping. The usable pH range of the mobile phase with the C18 stationary phase is from 2 to 12, providing durability equivalent to hybrid silica. A high-durability NH2 column has been added. 【Features】 ○ Superior alkali resistance compared to other hybrid C18 columns ○ Not affected by residual silanol groups ○ Exhibits good peak shapes for acidic, basic, and metal-coordinating compounds For more details, please contact us or download the catalog.

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ACE SuperC18 UHPLC & HPLC Column

SuperC18 UHPLC/HPLC column with expanded pH range due to unique encapsulation technology.

The ACE SuperC18 column is a UHPLC/HPLC column that expands the usable pH range (pH 1.5 to 11.5) compared to conventional C18 columns, thanks to the unique EBT technology (Encapsulated Bonding Technology) developed by ACT (Advanced Chromatography Technologies). The unique EBT technology dramatically increases the ligand coverage on the silica surface, eliminating the influence of unbound silanols, thereby enhancing inertness and stability. It is also designed for use with LC-MS buffers, providing ultra-low bleed to improve compatibility with LC-MS. It can be used with both methanol and acetonitrile as mobile phases, offering rapid column equilibration without memory effects. **Features** - Selectivity changes are available (in low, medium, and high pH ranges) - Excellent column life reduces costs - Usable with LC/MS compatible buffers - Recommended pH range: 1.5 to 11.5 - Compatibility with both methanol and acetonitrile - Fast column equilibration without memory effects

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ZORBAX Original Reverse Phase HPLC Column

It has a high activity level and helps in the separation of isomers and the improvement of selectivity!

We would like to introduce the "ZORBAX Original Reverse Phase HPLC Column" that we handle. Our lineup includes "ZORBAX C18," "ZORBAX C8," "ZORBAX-Phenyl," and others. These columns are manufactured using Type A silica and are useful for the separation of acidic or neutral compounds. Please feel free to consult us when you need assistance. 【ZORBAX C18 Specifications】 ■ZORBAX C18 - Pore Size: 70A - Surface Area: 300m²/g - Temperature Range: 60℃ - pH Range: 2.0-8.0 - End Cap: Yes - Carbon Content: 20% *For more details, please refer to the PDF document or feel free to contact us.

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[Data] RP-Amide HPLC/UHPLC Column

Improvement of retention for carboxylic acids and phenolic compounds! Achieving low bleed suitable for LC-MS applications.

This document provides an explanation of "RP-Amide HPLC/UHPLC columns." It introduces the "characteristics of RP-Amide," the "differences in retention for neutral analytes," and the "increased retention for hydrogen bond donors." Additionally, it includes analyses of "ulcer medications using Ascentis RP-Amide" and "UHPLC measurements of sunscreen drugs using Ascentis Express RP-Amide, 2.7μm." We encourage you to read it. 【Contents】 ■Ascentis RP-Amide HPLC column ■Analysis of ulcer medications using Ascentis RP-Amide ■UHPLC measurements of sunscreen drugs using Ascentis Express RP-Amide, 2.7μm ■Data sheet on the care and use of Ascentis Express RP-Amide columns ■LC/MS workflow products ■Ascentis RP-Amide product list ■Fused-Core product list *For more details, please refer to the PDF document or feel free to contact us.

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Silica-based column for HPLC/UHPLC "ACE Column"

High efficiency and high separation capability based on ultra-inactive silica. With a wide range of sizes and a rich lineup of bonding phases, we lead difficult separations to success.

Our company offers the 'ACE Columns' for HPLC/UHPLC, which are highly regarded for their reliability in countries around the world. Based on ultra-high purity silica, we have a range of products from the representative C18 type to various chemically modified options, with a rich lineup of gel particle sizes and column sizes. We achieve high efficiency, high separation capability, and long lifespan, making our columns recommended for those who are not obtaining desirable analytical results with their current columns or who wish to reduce column costs. 【Features】 - Uses ultra-high purity and inert silica - Available in particle sizes of 3, 5, 10, and 15 μm - Excellent reproducibility due to strict quality control - Theoretical plate number of over 200,000 plates/m - Available pore sizes of 100Å and 300Å - Various guard cartridge columns are also available to extend column lifespan *For more details, please refer to the PDF document (English version) or feel free to contact us.

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[Technical Data] Quality characteristic analysis of antibody drugs is settled with this!

The analysis of quality characteristics of antibody drugs is settled with this! For the analysis of important quality characteristics of antibody drugs!

The identification of critical quality attributes (CQAs) of antibody drugs, the establishment of their management scope, and their analysis can be effectively achieved using HPLC/UHPLC. We will introduce the TSKgel series (columns) used in the analysis of critical quality attributes and risk assessment of antibody drugs with UHPLC/HPLC.

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F5 (PFP) HPLC/UHPLC column

Separation of positional isomers using reverse phase and HILIC analysis! An additional step to add to C18 and HILIC columns.

The "F5 (PFP) HPLC/UHPLC column" for metabolomics is a reversed-phase column with selectivity different from C18. By incorporating it as a second or third choice column in reversed-phase systems, the range of substances for LC analysis is broadened. Four retention mechanisms—hydrogen bonding, dipole-dipole interactions, π-π interactions, and hydrophobic interactions—complexly influence each other to exhibit unique retention characteristics and stereoselectivity. 【Features】 ■ Retains highly polar basic compounds without ion-pair reagents ■ 100% water mobile phase is usable ■ Suitable for LC/MS due to retention at high organic solvent concentrations ■ Supports both analysis and fractionation *For more details, please refer to the PDF document or feel free to contact us.

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