GPC (Gel Permeation Chromatography) analysis
Measurement of the relative molecular weight and molecular weight distribution of polymers and oligomers.
This method utilizes the pores of a filler used as a stationary phase to separate sample molecules in order of increasing molecular size, and is also known as size exclusion chromatography (SEC). Larger molecules penetrate the pores of the gel less and move through the column and elute faster than smaller molecules. In this way, by separating and eluting based on molecular size, and using the differences in refractive index (RI) between the solvent and the sample solution or the absorption of functional groups (UV) to detect concentration, a distribution of molecules can be obtained.
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