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Column "AdvanceBio Peptide Mapping"

Column "AdvanceBio Peptide Mapping"

The particle size of 2.7μm allows for UHPLC performance in HPLC systems!

"AdvanceBio Peptide Mapping" is an LC column designed for biopharmaceutical analysis that provides high-resolution peptide maps for protein identification and post-translational modification measurement. Using this product, amino acid substitutions/modifications in the protein primary sequence can be rapidly separated and identified. This surface-porous advanced bio-column has a pore size of 120 Å, making it suitable for the analysis of peptides generated by enzymatic digestion of proteins. 【Features】 ■ Each batch is verified for stability and reproducibility using peptide standard substances. ■ Reliable analytical data can be obtained. ■ Identification of major peptides in complex peptide maps is possible. ■ UHPLC performance can be achieved with general HPLC equipment with a maximum pressure of 400 bar. ■ MS sensitivity is improved when using formic acid as the mobile phase in HPLC. *For more details, please refer to the PDF document or feel free to contact us.

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Column "AdvanceBio MS Spent Media"

Column "AdvanceBio MS Spent Media"

Rapid MS-based workflow! No need for sample derivatization, saving time and resources.

The "AdvanceBio MS Spent Media" is a HILIC column that can separate non-derivatized amino acids and other polar metabolites in cell culture media with high speed, excellent sensitivity, and reproducibility, making it suitable for mass spectrometry. By combining it with Agilent InfinityLab LC series instruments and Agilent MS instruments, a comprehensive solution for cell culture component analysis is achieved. The AdvanceBio MS Spent Media analysis is an innovative solution designed for the generation and characterization of biomolecules, as a new product in the Agilent AdvanceBio family. 【Features】 ■ Achieves excellent peak shape and recovery rates even for challenging ionic metabolites ■ Baseline chromatographic separation capability for isomers of leucine and isoleucine ■ Columns tested with amino acids to ensure quality and performance ■ Excellent analytical sensitivity with a mobile phase suitable for MS ■ Compatible with both HPLC and UHPLC systems *For more details, please refer to the PDF document or feel free to contact us.

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Column "AdvanceBio RP-mAb"

Column "AdvanceBio RP-mAb"

It can be analyzed in a shorter time compared to a column filled with all porous particles of the same size!

"AdvanceBio RP-mAb" is a column designed to optimize the performance of intact and reduced mAb analysis for the discovery, development, and QA/QC applications of biopharmaceuticals. Based on proprietary technology related to Poroshell technology and pore size and bonding phases, it provides accurate and reproducible analytical results with higher separation capability and faster analysis times. It accommodates various chemical properties such as SB-C8, C4, and diphenyl. 【Features】 ■ Enhances mAb separation capability with surface porous particles (3.5μm) of a wide pore size (450Å), while maintaining compatibility with all LC equipment. ■ Prevents inlet clogging and extends column life with robust Poroshell packing material and 2μ inlet frit. ■ Available in bonding phases of SB-C8, C4, and diphenyl. *For more details, please refer to the PDF document or feel free to contact us.

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Column "AdvanceBio Deionization RP Cartridge"

Column "AdvanceBio Deionization RP Cartridge"

Time-saving through online sample desalting! Concentrate the sample before elution.

The "AdvanceBio Desalting RP Cartridge" is a column that can efficiently and rapidly remove salt ions online before MS detection. It can be used in combination with any LC system to desalinate collected fractions. Additionally, it can be used with the Agilent 1290 Infinity II 2D-LC system, performing desalting on the second dimension after separation on the first dimension. 【Features】 ■ Reduced MS downtime and maintenance ■ Improved data quality and reliability of results ■ Large pore size of 1000 Å suitable for biopharmaceuticals ■ Stability from pH 2 to 13 ■ Compatible with commonly used reverse phase mobile phases *For more details, please refer to the PDF document or feel free to contact us.

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Column "ZORBAX 300Extend-C18"

Column "ZORBAX 300Extend-C18"

High robustness and separation of polypeptides and peptides over a wide range of pH from high pH to low pH (pH 2 to 11.5)!

The "ZORBAX 300Extend-C18" is a wide-bore HPLC column that efficiently separates peptides in the pH range of 2 to 11.5. Its unique bidentate bonding phase provides excellent longevity and reproducibility in both high and low pH regions. The retention characteristics and selectivity for peptides and polypeptides in the high pH region significantly change as these molecules become charged. 【Features】 ■ Shows different selectivity at high and low pH ■ Achieves excellent efficiency and good recovery rates for hydrophobic peptides at high pH ■ Suitable for LC/MS analysis using ammonium hydroxide mobile phase *For more details, please refer to the PDF document or feel free to contact us.

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Column "ZORBAX RRHD 300 HILIC"

Column "ZORBAX RRHD 300 HILIC"

The HILIC function is specially designed for the separation of glycopeptide variants!

The "ZORBAX RRHD 300 HILIC" is a column for the analysis of glycopeptides, featuring a particle size of 1.8μm and a pore size of 300Å. It is designed to provide consistent and outstanding performance for the separation and characterization of peptides, proteins, antibodies, complexes, novel biomaterials, and biopharmaceuticals. The technology of AdvanceBio columns enhances accuracy and productivity, allowing for more information to be obtained in various characterization analyses. 【Features】 ■ Excellent peak shape for polar glycopeptides - These polar compounds typically cannot be separated using reverse phase columns. ■ High-speed analysis and stability up to 1200 bar - With a particle size of 1.8μm, it enables fast separation using UHPLC without compromising data accuracy. *For more details, please refer to the PDF document or feel free to contact us.

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Column "ZORBAX RRHD - Wide Pore"

Column "ZORBAX RRHD - Wide Pore"

Achieving excellent separation capability with 1.8μm particles in most defined separations!

The "ZORBAX RRHD-Wide Pore" is an LC column suitable for the analysis of biopharmaceuticals, providing highly reproducible separations of proteins and peptides. To efficiently separate proteins, peptides, or other macromolecules, the sample needs to be in close proximity to the stationary phase surface, which is why such a wide pore (300Å) column is necessary. Four different stationary phases (C18/C8/C3/Diphenyl) are available, allowing for the optimization of selectivity and recovery rates for proteins and polypeptides. 【Features】 ■ High-pressure (1200 bar) column for obtaining suitable results with the 1290 Infinity LC or other UHPLC systems ■ Usable with HILIC Plus ■ The selectivity remains the same for 3.5μm and 5μm ZORBAX columns with the same stationary phase, ensuring compatibility with various LCs *For more details, please refer to the PDF document or feel free to contact us.

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