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Quantitative Phase Imaging (QPI) Microscope

Non-invasive live cell imaging - Zero-staining quantitative phase imaging "Q-Phase"

The Q-Phase by Telight is a quantitative phase imaging (QPI) microscope that employs patented Coherence Controlled Holographic (CCHD) technology. It measures and visualizes the dry mass and morphological changes of cells in real-time while minimizing phototoxicity and allowing for label-free imaging. This platform innovates long-term live cell analysis across pharmaceutical research, regenerative medicine, and mechanobiology. Typical applications include: - Drug discovery screening: Rapid assessment of cell proliferation inhibition and cytotoxicity based on dry mass changes after compound treatment. - Cancer research: Analysis of migration and invasion, as well as tracking EMT dynamics. - Immune cell analysis: Non-invasive monitoring of cell-cell interactions in co-culture systems. - Regenerative medicine / stem cells: Quantitative evaluation of morphological and mass shifts during differentiation induction. - Mechanobiology: High-contrast observation of 3D cultured cells within Matrigel or collagen matrices.

  • Optical microscope

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