コンフォーカルサイエンス List of Products and Services

"C-Clinic AD" is a comprehensive assistance service that solves problems related to protein crystallization experiments. We will listen to your issues regarding crystallization and provide appropriate "various crystallization reagent solutions" and "crystallization kits (GT method/capillary gel tube method)." After discussing the issues, we will send you optimized crystallization reagents. You will set up crystallization using the kit we provided, aiming to obtain good crystals. 【Features】 ■ Provision of crystallization reagents and tools ■ Compatibility evaluation of protein samples ■ Consideration of protein sample purification ■ Optimization of crystallization conditions for X-ray diffraction experiments ■ Optimization of conditions for large crystals *For more details, please refer to the PDF document or feel free to contact us.

• Other contract services

The "C-Collection" is a service for obtaining X-ray diffraction data of protein crystals using the mail-in service of the Diamond Light Source, a synchrotron facility in the UK. Customers can obtain diffraction data while remaining in their laboratories, and there are no long-term shutdowns, allowing for urgent data acquisition as well. You can leave the cumbersome procedures for exporting and importing protein crystal samples and applying for use of the Diamond Light Source to us. 【Features】 ■ No cumbersome procedures required ■ Fast data acquisition ■ Utilizes ultra-high-performance X-ray detectors ■ Data confidentiality ■ Options available for how to handle the crystals *For more details, please refer to the PDF document or feel free to contact us.

• Other contract services

"C-Profile" is a software tool that is useful for examining the purification and crystallization conditions of protein samples. Based on the amino acid sequence of the protein (in FASTA format), it calculates various physicochemical properties of the protein, such as molecular weight, pH dependence of charge/charge density, pI, ε, and GRAVY. It is provided as a macro file that operates in Microsoft Excel. 【Features】 ■ Provided as a Microsoft Excel file with macros ■ Operates on Microsoft Excel 2010/2013 installed on Windows 7 ■ Useful for examining the purification and crystallization conditions of protein samples ■ Performs calculations and displays results based on amino acid sequences in FASTA format ■ Allows for easy determination of weight concentration (mg/ml) from measured absorbance *For more details, please refer to the PDF document or feel free to contact us.

• Other Software

"C-Protein" is a highly purified protein sample with extremely enhanced uniformity, utilizing techniques such as ion exchange chromatography. We offer a lineup that includes highly purified lysozyme derived from chicken egg white, "MB-P-AA001," and highly purified glucose isomerase, "MB-P-AB001," among others. This product can be used as a standard sample in high-resolution X-ray diffraction experiments and more. 【Features】 ■ High quality ■ Utilizes ion exchange chromatography and other techniques ■ Sample with extremely enhanced uniformity ■ Can be used as a standard sample in high-resolution X-ray diffraction experiments and more *For more details, please refer to the PDF document or feel free to contact us.

• others

The "C-Tube LCDM" is a large protein crystal growth container with pre-connected gel tubes, allowing for easy filling and setup. It enables a dialysis method that alleviates the osmotic pressure difference with the reservoir solution, preventing diffusion leakage outside the container. By using the included gel immersion bags and crystallization bags, crystallization can be achieved in a minimal space. Additionally, the generated crystals remain stable for a long time within the capillary. 【Features】 ■ Dialysis and diffusion method ■ Protein sample volume ■ Easy filling ■ Long-term stability and space-saving ■ Crystallization conditions *For more details, please refer to the PDF document or feel free to contact us.

• Packaging materials and containers for bio-related products

This tool is a crystal generation tool using the counter-diffusion method (liquid-liquid diffusion method). No robots or special fixtures are required, and it can be easily set up without taking up storage space. Additionally, using a gel-filled silicone tube (gel tube) makes setup easier. 【Features】 ■ Inexpensive and compact ■ Easy filling ■ Small amount of protein sample ■ Mild crystallization conditions *For more details, please refer to the catalog or feel free to contact us.

• Other experimental equipment