パトコア List of Products and Services

Design HUB is a groundbreaking information platform that integrates "hypothesis-driven" and "data-driven" approaches to streamline the DMTA (Design, Make, Test, Analyze) cycle in the early stages of drug discovery. It also functions as a content hub, enhancing the efficiency and success rate of the entire drug discovery process. Furthermore, it provides secure information-sharing capabilities to facilitate collaboration with external CROs and universities, supporting the efficient advancement of project tasks. **Features** - **Compound Design and Real-Time Analysis** - Can be used as a personal workstation or for brainstorming among multiple scientists - Displays real-time information on the properties of drawn structures and known similar compounds - Rapidly reviews ideas through comparisons and filtering with existing compound library data, as well as examining pharmacophore models by drawing three-dimensional structures *For more details, please refer to the PDF materials or feel free to contact us.*

"AMEDEO" functions as an idea generator that allows non-experts to easily utilize advanced tools available in data science (AI and machine learning) to accelerate the lead optimization cycle. It learns about the data and builds and selects predictive models. It then clearly suggests which compounds should be created next. By simply answering a few easy questions regarding goals such as optimization items, it proposes candidates for biopharmaceuticals or small molecule drugs. 【Features】 ■ Idea generator to accelerate the lead optimization cycle ■ Learns about data and builds and selects predictive models ■ Clearly suggests which compounds should be created next ■ Just answer a few easy questions regarding goals such as optimization items ■ Proposes candidates for biopharmaceuticals or small molecule drugs *For more details, please refer to the PDF document or feel free to contact us.

"Compound Registration" is a system built on a series of web services. For new low molecular weight compounds, it compares them with compounds already stored in the database to confirm uniqueness and assigns compound numbers and lot numbers. The determination of uniqueness is carried out according to the business logic of the configurable companies. 【Features】 ■ A system built on a series of web services ■ Includes a database designed to store related structural information and accompanying data ■ If issues cannot be automatically resolved, they are classified into a staging area ■ Upon successful registration, compounds can be stored in a three-level hierarchy *For more details, please refer to the PDF materials or feel free to contact us.

PatCore provides a series of business logic necessary for compound registration as a web service. 'PatRegi|SM' flexibly accommodates various business policies of different companies through detailed configuration features. Requirements definition and business rules are templated, allowing for system implementation in a short period. 【Features】 ■ Flexible response to diverse business policies through detailed configuration features ■ Well-suited for compound registration from electronic lab notebooks ■ Linked with the regulatory check system CRAIS Checker ■ Manual registration from Instant JChem and bulk registration from SDF are possible *For more details, please refer to the PDF document or feel free to contact us.

"Plexus Connect" is the central component of the tool "Plexus Suite," which allows for the display, search, and analysis of scientific data. It provides a multi-user web access environment to the Instant JChem (IJC) database. The grid view or form view generated in IJC can be opened in a browser and supports most IJC widgets. You can view, sort, and search chemical structures and alphanumeric data, as well as save lists of queries and search results. 【Features】 ■ Central component of Plexus Suite ■ Can be opened in a browser and supports most IJC widgets ■ Allows viewing, sorting, and searching of chemical structures and alphanumeric data, as well as saving lists of queries and search results *For more details, please refer to the related links or feel free to contact us.

"Marvin Sketch" is a Java-based structure drawing tool. With intuitive operations, it allows for the drawing of structures, reactions, and queries. It can be used as a standalone drawing tool, and it can also be integrated into web applications and custom applications. 【Features】 ■ Intuitive operations enable the drawing of structures, reactions, and queries ■ Supports reading and writing various file formats ■ Can copy and paste from Chem Draw Pro, ISIS/Draw, and others ■ Marvin supports various structure data formats *For more details, please refer to the related links or feel free to contact us.

"SARvision SM" is software that supports chemists in one of their important tasks: the examination of structure-activity relationships. With its unique Maximum Common Substructure (MCS) extraction engine, it can classify chemical structure data by scaffold, making SAR analysis easier. Scaffold-based data mining allows for evaluations that are closer to a chemist's intuition compared to descriptor-based clustering, proving effective in assessing screening data and formulating synthetic strategies during the Hit to Lead and lead optimization stages. 【NEW!】 A PROTAC analysis module has been released, allowing for routine and easy execution of SAR studies for bivalent ligands. For details, please visit the product page. 【Features】 ■ Automatically extracts common substructures from a group of structural formulas and presents a tree classified by scaffold. ■ Sorts scaffolds by physical properties or activity data, and allows dynamic filtering using sliders. ■ Rich graphic features (bar graphs, 2D scatter plots, 3D scatter plots). *For more information, please refer to the related links or feel free to contact us.

"SARvision Biologics" is a desktop application that fills the gaps in existing biologics software. It provides foundational tools for reading and organizing data on biopolymers, as well as various tools to discover the relationships between sequences and activities. A spreadsheet optimized for sequence analysis is provided, allowing for the handling of biopolymers such as nucleic acids, proteins, and peptides, including non-natural amino acids and chemically modified residues. 【Features】 ■ Supports research on peptides, antibodies, and RNA ■ Capable of handling peptides that include non-natural amino acids, cyclization, and chemical modifications ■ Visualization of activity through heat maps ■ Highlights areas of interest *For more details, please refer to the PDF materials or feel free to contact us.

"JChem for Office Lite" is a lightweight desktop application that allows users to utilize "live structures" seamlessly within MS Office. Users can choose their favorite chemical editor for displaying and editing chemical structures. It is suitable for users who simply want to copy and paste chemical structures from the editor into Office applications, and the pasted structures can be edited seamlessly just like in JChem for Office. 【Features】 - Operates lightly and smoothly by eliminating the ribbon and advanced chemical function options of JChem for Office. - Uses a suitable renderer for the given format. - Applies renderer-specific drawing styles regardless of the structure format. - Changing the renderer and editor can be easily done from the context menu. *For more details, please refer to the related links or feel free to contact us.

The long-selling chemical add-in "JChem for Excel" has been renewed as "JChem for Office," which now supports not only Excel but also Word, PowerPoint, OneNote, and Outlook Mail. It is compatible with Microsoft Office 2010, 2013, and 2016. The previous Excel chemical add-in was heavy and lacked stability, but with this product, you can handle large volumes of chemical data more efficiently. 【Features】 ■ Ability to load data from projects selected in Instant JChem ■ Can import datasets from Oracle and MySQL databases ■ Usable for extracting chemical information from patent documents, etc., through integration with Document to Structure ■ KNIME nodes and PP components are also available for handling JChem for Excel workbooks in batch mode *For more details, please refer to the related links or feel free to contact us.

●Unmatched data quality and scale GOSTAR is one of the world's largest databases of low molecular weight compounds, curated manually by top experts. It is organized, integrated, and updated through manual curation, allowing for immediate use in analysis and AI model development. By using GOSTAR, you can free yourself from the tasks of collecting and organizing data, enabling you to focus your valuable time on the most important research activities. GOSTAR is one of the largest low molecular SAR databases in the world, containing approximately 9 million low molecular weight compounds and nearly 30 million SAR data points. The database is built from 80,000 patents filtered from about 40 million and 200,000 research articles filtered from about 10 million, with data extracted through manual work by experts and standardized and structured based on specified rules. 【Features】 ■ A centralized data source for one of the largest low molecular SAR information collections in the world ■ Automatically adjusted for display based on the type of ligand, making it easy to read ■ Sortable by any data column and color-coded based on values *For more details, please refer to the PDF materials or feel free to contact us.*

Standard knowledge bases often cannot solve the specific challenges faced by customers. Excelra's senior experts and consultants understand the specific issues of customers and provide tailored solutions that meet their precise needs. Excelra has the expertise and experience to extract, structure, and organize unstructured data, transforming it into high-quality formats suitable for analysis, enabling data-driven decision-making based on information in drug discovery. When handling customer data, we adhere to the highest standards of data privacy and confidentiality, as proven by over a decade of partnerships with top-tier pharmaceutical companies and scientific publishers. We respond flexibly to short turnaround jobs without compromising on quality.

Marvin has achieved a user-friendly interface that can instantly convert users' thoughts into visual representations by combining top-level chemical intelligence with the latest front-end frameworks. It is not only capable of drawing structures easily and efficiently but also serves as an ideal solution for users who want to create beautiful and attractive illustrations. It enables the efforts spent on research to be quickly transformed into high-quality chemical drawings. 【Features】 ■ Publication-level visual quality ■ Accurate and rapid drawing of structural formulas and chemical schemes through chemical intelligence ■ High-performance web components *For more details, please refer to the PDF materials or feel free to contact us.

"Quick Request" is a testing request system that solves various issues related to test requests and realizes an efficient laboratory. It can manage the increasing number of compounds, diversifying and complicating tests, and various other tasks all in one system. Not only can you visually confirm the tests you are handling, but by consolidating communication channels between the requesting department and the testing department, it is possible to prevent communication and coordination errors in advance. 【Features】 ■ Flexible workflow ■ Access control tailored to operational forms ■ Visualization of testing status ■ Various options to enhance usability *For more details, please refer to the PDF materials or feel free to contact us.

■One of the largest and most reliable databases in the industry GOSTAR TPD is a specialized database that encompasses detailed structural information, activity data, and target protein information for over 51,000 target decomposition inducing agents (TPD) compounds. This product is certified with QMS (Quality Management System) and provides the latest and most reliable data through regular monthly updates. Researchers can quickly identify TPD compounds that meet their objectives using a flexible search function that combines multiple conditions of structure, target, and activity. It significantly reduces the effort of manually searching through vast literature and complex data. GOSTAR TPD dramatically improves the quality and speed of drug discovery research, strongly supporting the discovery of new therapeutic drugs. It provides an environment where complex TPD-related data can be understood simply and deeply, allowing researchers to focus on the core tasks of drug discovery. 【Features】 ■One of the largest domestic databases specializing in TPD structure, activity, and target ■High-quality data updated monthly, compatible with AI drug discovery ■Intuitive search UI maximizes research efficiency *For more details, please refer to the PDF materials or feel free to contact us.*