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大塚化学

addressTokyo/Chiyoda-ku/2-2 Kanda Tsukasa-cho, Otsuka Pharmaceutical Kanda No. 2 Building
phone03-5297-2727
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last updated:Jun 24, 2025
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Pharmaceutical-related

It is widely used as a pharmaceutical synthesis raw material and intermediate, as well as a synthetic reagent.

Aromatic compounds

A group of compounds expected to have a wide variety of applications, such as pharmaceutical and pesticide raw materials, as well as functional polymer materials!

Aromatic compounds are a group of compounds expected to have a wide range of applications in the field of fine chemicals, such as pharmaceutical and pesticide raw materials, functional polymer materials, or polymer additives. Synthesis methods involve combining various synthetic reactions, such as organic electrochemical synthesis reactions, catalytic redox reactions, and metal-mediated organic synthesis reactions, according to their intended purpose. If you have any questions or inquiries about chemical products that can be used in your own products, please feel free to contact us. [Features] ■ An organic synthesis method that allows for precise control of redox reactions, usable for stepwise oxidation reactions of aromatic side chains, special reduction reactions, and special alkylation reactions. ■ Establishment of catalytic redox reactions and metal-mediated organic synthesis techniques. ■ A group of compounds expected to have a wide range of applications. *For more details, please refer to the PDF materials or feel free to contact us.

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Inorganic chemicals

We handle various products such as potassium nitrate, potassium chloride, and sodium chloride!

In the "inorganic chemicals" we handle, we offer grades tailored to various applications to meet our customers' needs. We provide products such as "potassium nitrate," used in the manufacture of explosives, fireworks, and pyrotechnics, as well as glazes for ceramics, "potassium sulfate," a nutrient source for fermentation microorganisms, and "potassium chloride," used as a raw material for potassium metal products and various industrial raw materials. If you have any questions or inquiries about chemical products that can be used in your own products, please feel free to contact us. 【Inorganic Chemical Products】 ■ Potassium Nitrate ■ Potassium Chloride ■ Sodium Chloride ■ Potassium Sulfate ■ Calcium Chloride Dihydrate, etc. *For more details, please refer to the PDF materials or feel free to contact us.

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Pharmaceutical CDMO services

We support consistent quality control from raw materials to active pharmaceutical ingredients, including method development and stability testing!

Otsuka Chemical Co., Ltd. offers pharmaceutical CDMO services. Utilizing organic synthesis technology cultivated over many years in pharmaceutical manufacturing, we provide a consistent service from special raw materials to intermediates and mid-sized active pharmaceutical ingredients. With over 60 years of experience in halogenation technology and our unique catalyst development technology, we respond to diverse needs. Please feel free to contact us when you need our services. 【Features】 ■ High pharmacological activity (OEB Category 4) with solid-phase synthesis / flow synthesis capabilities Newly established GMP-compliant multi-purpose plant ■ Consistent service from special raw materials to intermediates and mid-sized active pharmaceutical ingredients ■ Responding to diverse needs through halogenation technology and unique catalyst development technology *For more details, please refer to the PDF document or feel free to contact us.

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Notice of Hybrid Seminar on April 26, 2024 (Friday)

The forefront of mid-sized molecular medicine! The latest research and technologies in fluorination, flow synthesis, and computational science are the themes.

We are pleased to announce that on April 26 (Friday), we will be co-hosting a free hybrid seminar titled "The Cutting Edge of Mid-Molecule Pharmaceuticals - Latest Research and Technologies in Fluorination, Flow Synthesis, and Computational Science" in collaboration with Otsuka Chemical and Syncrest. On the day of the event, there will be presentations from Ryukyu University, Nagoya University, and Syncrest Corporation, followed by a Q&A session. We sincerely look forward to the participation of many of you. This seminar is a must-attend for those interested in organic chemical synthesis research and its implementation technologies aimed at drug discovery. 【Seminar Overview】 ■ Date and Time: April 26, 2024 (Friday) from 14:00 to 15:50 (scheduled to end) * Networking event & lab tour: 16:00 to 17:00 (scheduled to end) ■ Theme: "The Cutting Edge of Mid-Molecule Pharmaceuticals - Latest Research and Technologies in Fluorination, Flow Synthesis, and Computational Science" ■ Participation Fee: Free ■ Format: In-person (Shonan i-Park), WEB (Zoom) *For more details, please refer to the related links or feel free to contact us.

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Pharmaceutical raw materials and intermediates / Food additives, etc.

Development of β-lactam compounds and p-substituted aromatic compounds! Expansion into various fields such as pharmaceuticals and the food industry.

Our company handles reaction promoters for synthesizing amide bonds, such as pharmaceutical intermediates, functional resins, and peptide synthesis. Beyond the pharmaceutical business, our life science products are expanding their applications, primarily contributing to your daily life through food additives, fragrances, and hair care ingredients. We also offer a variety of β-lactam compounds, including GCLE, an intermediate for cephalosporin antibiotics. 【Products Offered】 ■ β-lactam compounds ■ Pharmaceutical raw materials and intermediates ■ Fragrances and hair care ingredients *For more details, please download the PDF or feel free to contact us.

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Contract manufacturing (pharmaceuticals/chemicals)

Manufacturing compatible with Category 5 of the Fire Service Act! We have a track record of producing various hydrazine derivatives.

Otsuka Chemical Co., Ltd. has been developing contract manufacturing businesses for chemicals and pharmaceuticals based on the technological capabilities cultivated since its establishment in 1921. We understand the individual needs and quality requirements of our customers, as well as the demands of each industry, and we realize product development that satisfies our customers under thorough quality control. In chemical manufacturing, we provide consistent support from research and development to mass production, enabling our customers to realize their products. In pharmaceutical manufacturing, we respond to a wide range of contract needs centered around our CRDMO services, which allow for consistent handling from raw materials to active pharmaceutical ingredients, from research stages to manufacturing stages. 【Features】 ■ Capable of handling/manufacturing hazardous materials classified as Type 5 under the Fire Service Act, with designated quantities exceeding 100 times ■ Automatic control via DCS and monitoring of pressure/temperature, etc. ■ Low-temperature reaction vessels allow for reactions at -25°C using CBR equipment ■ Proven track record in thermal filtration and activated carbon removal at high temperatures ■ Explosion-proof centrifugal separators with Ti lining enable solid-liquid separation of organic solvents and acidic substances *For more details, please download the PDF or feel free to contact us.

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