日本ウォーターズ（米国本社 Waters Corporation）　 List of News Articles

We will hold a webinar series delivering knowledge and know-how about GPC/SEC over four sessions. GPC/SEC is highly specialized and requires specific skills to use correctly. In this series, we will carefully explain common questions and challenges faced by GPC/SEC users, covering everything from basic principles to equipment and column management, calibration, molecular weight calculation, and troubleshooting, with the aim of enhancing your ability to handle these issues independently after viewing. We will also introduce support systems to facilitate analysis operations, as well as examples of the latest technologies combined with ultra-fast GPC systems and mass spectrometers (MS). Session 1: Basics of GPC/SEC Date: October 7 (Tuesday) Session 2: Calibration Curves for GPC/SEC Date: October 21 (Tuesday) Session 3: Molecular Weight Calculation for GPC/SEC Date: November 4 (Tuesday) Session 4: Troubleshooting for GPC/SEC Date: December 2 (Tuesday) All sessions: 15:00 - 16:00

We are currently holding a nitrosamine analysis observation event year-round at our Tokyo headquarters and Osaka branch showrooms. After confirming your preferred date, we will adjust the schedule and generally guide one group per day. Please send the following necessary information via the inquiry form on this page to apply: ■ Preferred venue (Tokyo or Osaka) ■ Preferred date - First choice ■ Preferred date - Second choice ■ Expected number of participants (up to 5 people) ■ Other requests By clicking [Send], you are deemed to have agreed to Waters' use and processing of the information provided on this site in accordance with Waters' Terms of Use and Privacy Notice. Terms of Use and Privacy Notice www.waters.com/legalandprivacy

Xevo TQ Absolute is a robust LC-MS/MS that allows for easy quantification of challenging compounds with absolute sensitivity and reliability. ■ Application Notes Please contact us if you are interested. - High-sensitivity bioanalysis of low molecular weight pharmaceuticals - Bioanalysis of oligonucleotide drugs - High-sensitivity analysis of mutagenic boronic acids - Analysis of free testosterone in serum - Quantification of N-nitrosamines - Analysis of carboxy-THC in hair - Analysis of drugs in blood for toxicological investigations - Speciation analysis of gelatin - Analysis of anionic polar pesticides in food - Measurement of glyphosate, aminomethylphosphonic acid (AMPA), and glufosinate in drinking water - Measurement of chlorates, perchlorates, and bromates in food - Analysis of PFAS (method development and evaluation, in drinking water, aqueous matrices, soil and tissue, vegetables, fruits, baby food, animal products, etc.)

No compromise on performance or speed, the cutting-edge QTof Xevo MRT mass spectrometer ■ Brochures and Application Notes Please contact us if you wish to receive them. (Some materials are available in English only) - High-throughput lipidomics workflow using Xevo MRT - Improved throughput while maintaining the reliability of lipidomics identification results with ballistic gradient, vacuum-jacketed columns, and MRT - Screening of extracellular vesicle metabolomics using Xevo MRT - Exploratory lipidomics testing for colorectal cancer using Xevo MRT mass spectrometer and Lipostar data analysis workflow product solutions - Mapping of phosphorylation of peptide biomarkers corresponding to glioblastoma using DDA and Xevo MRT - High-sensitivity high-throughput LC-MS analysis of eicosanoids using Xevo MRT - Feasibility of single-cell lipidomics using Xevo MRT - Metabolomics workflow using Xevo MRT

We will introduce the analysis and structural analysis of organic fluorine materials. Here, you can see a variety of approaches equipped with attachments such as a high-resolution mass spectrometer, a ring-shaped ion mobility cell, direct probes, and imaging. The keyword "organic fluorine materials" imparts unique properties to compounds due to the size and electronegativity of the atoms, but it also has the troublesome aspect of being difficult to analyze by mass spectrometry due to the absence of isotopes. Don't miss the opportunity to participate in this spicy webinar that skillfully tackles these fluorines. Program: ■ Features and overview of cIMS ■ Introduction of ion source options for material sample analysis ■ Examples of structural analysis of organic fluorine compounds Target Audience: Individuals using precision mass spectrometry in various fields such as pesticides, pharmaceuticals, and chemical industry.

Achieving reliable trace quantification through matrix removal of various samples Sample pretreatment to enhance further cleanup effects With the advent of high-sensitivity analytical instruments, the importance of sample pretreatment, such as concentration and cleanup, is increasing. Matrix removal from various samples is essential for achieving more reliable trace quantification. In this live webinar, we will introduce the OASIS mixed-mode method development for enhancing cleanup effects. The Oasis 2×4 method is designed so that by selecting one of the four types of mixed-mode solid phases based on the chemical properties of the target component and implementing the recommended protocol for that solid phase, good results can be obtained. Program: - The necessity of sample pretreatment - Solid-phase extraction for matrix removal - Mixed-mode solid phase for further advanced cleanup - Oasis 2×4 method development

Photosensitive resins and materials that change with light have been developed to exhibit various functions suitable for applications such as coatings, biocompatible materials for medical use, electronic materials, and cosmetics. To achieve the desired physical properties, molecular-level interpretations are necessary, including molecular design of polymers and initiators, light absorption and activation, and control of reactivity. This seminar will introduce photosensitive materials, focusing on the changes in compounds before and after curing of light-curable resins using Tof MS, as well as the structural analysis applications of photogenerated acids and their impurities. Program: ■ Overview of photosensitive materials ■ Identification approaches for variable factor components using high-resolution mass spectrometry ■ Analysis of variations and structural estimation before and after curing of light-curable resins ■ Workflow for extraction and structural estimation of trace impurities ■ Structural analysis and impurity identification of photogenerated acids Target Audience: Individuals handling organic compounds for the development and quality control of materials and industrial products.

In recent years, with the advancement and enhancement of polymer materials, various additives for synthetic polymers with different functions have been used in optimized formulations. Among them, there are types of additives, such as hindered amine light stabilizers (HALS) and lubricants, that present challenges in solubility and detection methods, making analysis difficult. Additionally, when conducting structural analysis of multi-component polymers or terminal group analysis using pyrolysis gas chromatography-mass spectrometry (PyGC/MS), there are many pyrolysis products not registered in the EI method database, making analysis not straightforward. In this webinar, we will introduce two solutions to the challenges in the characterization of synthetic resins, along with practical examples. ■ Overview of additives for synthetic polymers ■ Actual quantitative analysis of HALS/lubricants ■ Examples of structural analysis of synthetic resins using PyGC/Q-Tof MS Target audience: Individuals handling organic compounds for the development and quality control of materials and industrial products.

When assessing the safety and efficacy of pharmaceuticals, the quality and robustness of analytical data are extremely important. The currently discussed ICH guidelines are considering a lifecycle approach to improve the consistency and robustness of analytical method quality over the long term. By deploying the developed analytical methods to quality control labs using the latest HPLC, it is possible to reduce OOS (Out of Specification) and OOT (Out of Trend) occurrences. In this webinar, we will explain the challenges of routine analysis in quality control labs and their solutions. We will also introduce a new product, Arc HPLC, which allows for a smooth transfer of existing LC analytical methods and enables the acquisition of higher quality data.

Compounds or their metabolites found in pharmaceuticals, cosmetics, and food can have high hydrophilicity. In environmental monitoring, hydrophilic and highly polar compounds may also be targeted in water system environmental analysis. Since these compounds are difficult to analyze using conventional reverse phase chromatography, hydrophilic interaction chromatography (HILIC) is often suitable. On the other hand, many people may think, "It sounds complicated just by the name," and have not yet tried HILIC, or they may not be satisfied with their current HILIC analysis. In this seminar, we will introduce the principles of HILIC analysis, key points for method development, and columns suitable for HILIC analysis. Program: ■ Basics of HILIC mode ■ Development of HILIC analytical methods ■ Columns suitable for HILIC mode and analysis examples Target Audience: ■ Those analyzing highly polar and hydrophilic compounds ■ Those planning to conduct analyses in the future ■ Those considering improvements to their current HILIC analysis

The molecular weight distribution and additives of polymer materials are significant factors that greatly contribute to the physical properties and lifespan of the materials, making them widely analyzed from material development to quality control. Typically, these two analyses employ different separation modes, requiring dedicated systems and separate pretreatment methods. However, efficiency can be improved by conducting both analyses in a single analysis using the same pretreatment sample. In this webinar, you will learn about the new technology of GPC/MS and the application of simultaneous measurement of molecular weight distribution and additive quantification. Main content of the webinar: ■ Principles and advantages of high-resolution GPC ■ How to utilize GPC + RI detector + MS detector ■ Simultaneous analysis methods and approaches for molecular weight distribution and additive quantification Target audience: ■ Those using GPC systems ■ Those using LC, LC/MS, and GC/MS for additive analysis ■ Individuals involved in research and development, quality assurance, and management of polymer materials Program: ■ Measurement of molecular weight distribution and additive quantification in polymer materials ■ Principles and characteristics of high-resolution GPC ■ Challenges in GPC/MS systems and analysis ■ Case studies of simultaneous analysis of molecular weight distribution and additives

Starting Here: LC Course ~Intermediate Edition: Efficient Analysis with Chromatographs Tailored to Applications~ When it comes to chromatographs (high-performance liquid chromatography systems), there are various types available depending on their applications. General-purpose analyzers, low-dispersion types, and those with multiple flow paths are just a few examples. The characteristics of a chromatograph significantly influence the analyzable conditions and results. Additionally, using a chromatograph that is not suited for the intended application can lead to inefficiencies, such as prolonged analysis times and unnecessary costs. In this webinar, we will explain the features of each chromatograph, their applications, and their impact on analysis. Program: - Classification of chromatographs - Impact of chromatographs on separation - How to choose a chromatograph based on application

Starting Here: LC Course ~ Beginner's Edition: Basics of LC and Analytical Columns ~ Liquid chromatography (LC) is an essential technology in pharmaceuticals, cosmetics, chemical products, food, environmental fields, and various inspections and tests. On the other hand, you might feel apprehensive, thinking, "Isn't this a complicated technology?" In this webinar, we will explain the basics of LC and the analytical columns that are central to separation. We encourage those who are new to LC to actively participate. Program: - What is chromatography? - Representative separation modes of HPLC - Basics of analytical columns

Rapid and reproducible analysis of high-polarity pesticides without derivatization Waters' Anionic Polar Pesticide Column has been developed to provide a reliable analytical method when combined with Waters UPLC-MS/MS technology. Dedicated columns for applications targeting substances like glyphosate enable excellent retention, peak shape, and separation of a range of anionic polar pesticides without the need for derivatization. We will also introduce the latest tandem quadrupole mass spectrometer used for this analysis. Program - Challenges in the analysis of glyphosate - Introduction of the Anionic Polar Pesticides (APP) column - Challenges (retention, separation, reliability, detection) - Analytical methods and reliability of the APP column - Introduction of the latest tandem quadrupole mass spectrometer

"Smart MS" BioAccord System Latest Information Webinar We will hold a WEB seminar (on-demand) introducing the product overview of the BioAccord LC-MS system, which supports routine analysis of biopharmaceuticals, peptide drugs, and nucleic acid drugs. Additionally, we will explain the Multi Attribute Method (MAM), analysis of nucleic acid drugs, and new applications for adeno-associated viruses (AAV).

Waters provides total solutions to support customers from sample preparation in food analysis and separation by high-performance liquid chromatography to mass spectrometry. In this webinar, we will introduce the basics of sample preparation methods, including examples of positive list simultaneous analysis, as well as analysis examples using LC/MS/MS. We will also showcase the latest Waters sample preparation equipment, such as the pressure-controlled manifold (Otto SPEcialist pressure manifold) and automatic liquid handling (Andrew Alliance). Program: ■ The necessity of sample preparation ■ Examples of food analysis applications using solid-phase extraction and QuEChERS methods ■ Introduction of the latest Waters sample preparation equipment - Otto SPEcialist pressure manifold - Waters amino acid analysis method and automatic liquid handling

Waters has developed the robust single quadrupole mass spectrometer RADIAN ASAP, equipped with the atmospheric pressure solid sample analysis probe (ASAP) ionization method, specifically designed for rapid, easy, and low-cost analysis of liquids and solids. It can directly ionize samples from liquids or solids, making it suitable for a wide range of applications and workflows. With excellent flexibility, operability, and speed, the RADIAN ASAP does not require complex sample pretreatment, separation, or analytical experience, helping you achieve more results. The multivariate analysis-capable LiveID software allows for real-time classification of samples analyzed with the RADIAN ASAP. Analytical results are immediately provided to the user, enabling instant decision-making based on the analytical information. In this webinar, we will first cover the basics of mass spectrometry, followed by an introduction to the principles, usage, features, and actual analysis cases of the RADIAN ASAP. Program: ■ Overview of mass spectrometry ■ Overview, usage, and features of RADIAN ASAP ■ Analysis cases in pharmaceuticals, chemistry, food, and forensics