How can we streamline the creation of separation methods for active pharmaceutical ingredients and nitrosamines? Nitrosamine Analysis Workshop [Tokyo, Osaka]

The self-inspection period will soon end. Are you ready for the upcoming operations?

The self-inspection regarding the contamination of nitrosamines in pharmaceuticals, notified by the Ministry of Health, Labour and Welfare in October 2021, has a deadline of August 1, 2025. By the deadline, it is necessary to measure the amount of nitrosamines contained in items at risk of contamination, and if the levels exceed the limit, risk reduction measures such as setting standard values must be taken. When setting standard values for nitrosamines, it is essential to use systems and analytical conditions that enable high-sensitivity analysis, and we also want the systems to have the robustness to withstand daily analysis. Waters supports high-sensitivity and robust analysis of nitrosamines with total solutions including high-sensitivity and robust mass spectrometers, LC systems and columns that achieve high separation, and informatics, as a specialized manufacturer of LC and mass spectrometry. By clicking [Submit], you are deemed to have agreed that Waters will use and process the information provided on this site in accordance with Waters' Terms of Use and Privacy Notice. Terms of Use and Privacy Notice www.waters.com/legalandprivacy

• Liquid Chromatograph
• Mass Spectrometer
• High Performance Liquid Chromatograph

Are you satisfied with just high sensitivity? - Ultra-high sensitivity LC-MS/MS that maintains stable operation for a long time and is easy to maintain.

Many people are struggling with systems that are prone to contamination and time-consuming maintenance. The Xevo TQ Absolute, known for its resistance to contamination thanks to the "ZSpray Ion Source," along with a new source shield, minimizes contamination of the ion source from sample matrices and salts in the mobile phase. It also allows for the removal of neutral molecules before the mass separation section (StepWave XS), concentrating ions for introduction into the mass separation section. This helps maintain the system in a "good condition" for a longer period, maximizing uptime. As a latest high-sensitivity model, it achieves higher sensitivity and lower quantitation limits. Additionally, it is more compact compared to conventional products, reducing power and gas consumption by about 50%, and also decreasing heat generation by approximately 50%. 【Features】 - Sensitivity to anionic compounds improved by up to 15 times (compared to previous products) - Ensures consistent robustness and reproducibility, maintaining performance and productivity over a longer period - Reduces electricity and gas consumption by about 50% compared to typical high-performance TQ mass spectrometers, with heat generation also reduced by about 50%

• Analytical Equipment and Devices
• Mass Spectrometer

Reliable characteristic analysis - A mass spectrometer that maximizes information about the analysis species.

By using the Xevo G3 QTof, you can maximize the information about the analysis species from samples, enhancing the reliability of results from detailed characterization to accurate quantification. It simplifies and expands the characterization and evaluation of properties, from unstable low molecular weight compounds to complex biopharmaceuticals. By updating the design of the ion optical system and incorporating core technologies that achieve comprehensive quantification capabilities, consistent robustness and performance have been achieved. 【Features】 - Improved permeability of unstable low molecular compounds maximizes coverage of analysis species - Enhanced quantitativeness and expanded dynamic range within and between spectra enable optimal comprehensive quantification/qualitative analysis for screening and target applications - Improvements in the ion optical system lead to a more reliable and robust system - Achieves high levels of accuracy and reproducibility

• Analytical Equipment and Devices

Solving non-specific sample adsorption! Improved peak shape and sensitivity with new technology, featuring low adsorption and bio-inert LC with excellent reproducibility and durability.

The ACQUITY Premier system incorporates the new MaxPeak High Performance Surfaces (HPS) technology, which effectively reduces sample loss due to nonspecific adsorption caused by interactions with metals, while providing the following benefits: ■ Ideal for the analysis of organic acids, organophosphates, oligonucleotides, peptides, glycoproteins, phospholipids, veterinary drugs, chelating agents, and more. ■ Improved sensitivity and reduced risk of peak omission. ■ Elimination of column and system passivation and conditioning, saving time and costs. ■ Enhanced reproducibility and reliability of results. A variety of low-adsorption columns featuring MaxPeak High Performance Surfaces (HPS) technology are also available. When used in combination with the system, they enable more reliable analyses. *We also offer online briefings and demonstrations, so please feel free to contact us.

• Analytical Equipment and Devices

Fukuda Corporation has been pursuing leak detection for 60 years and is dedicated to advancing the future of leak testing. 【 Supporting Various Leak Tests: Air Leak Test / Gas Leak Test (Hydrogen Gas, Helium Gas) 】 We develop, manufacture, and sell leak testing equipment to inspect airtightness and sealing performance. We will propose suitable testers and devices for each inspection target. 【 Target Industries and Examples of Inspection Targets 】 - Automotive Industry: Engines, FC components, valves and piping, various parts - Electronic Components Industry: Smartphones, keyless switches, various small sensors - Pharmaceuticals / Food / Cosmetics Industry: Bottle containers, syringes, vials, eye drop containers, pillow packaging, PTP packaging We will propose the most suitable leak testers for each industry. 【 ISO Certification 】JIS Q 9001:2015 (ISO 9001:2015)

This is a collection of links to Fukuda's technical columns. It covers various topics related to leak tests and more... Please check the related links for more information.

In a civil engineering site material yard, not only is material storage conducted, but also the frequent movement of trucks and heavy machinery, unloading, and the movement of workers. On unpaved ground, mud and ruts can occur due to rain, which may reduce work efficiency. Hyper CLT mats are civil engineering CLT materials that utilize wood CLT. By laying them in material yards or storage areas, a work space that facilitates the movement of vehicles and heavy machinery can be established while protecting the ground. They can be laid only in necessary locations, and relocation or repurposing in accordance with construction progress is also possible. The 5×10 panel weighs approximately 230 kg, and the 5×20 panel weighs about 460 kg, making them lightweight and easy to install and remove even with small machinery. After use, they can also be utilized as temporary roads, access routes, or heavy machinery work yards. Additionally, they offer unique benefits of wood, such as glare reduction, noise suppression, and CO2 fixation. As a registered technology with the Ministry of Land, Infrastructure, Transport and Tourism under NETIS "TH-250021-A," these wooden mats can also be used for environmental improvement in material yards and innovative public works.

Features: ● Equipped with Intel Core Processor (Series 3) ● Onboard LPDDR5 memory: up to 24GB ● Onboard UFS storage: up to 256GB ● 2.5GbE (2.5 Gigabit Ethernet): 1 port ● HDMI 2.1 (TMDS): 1 port ● USB 3.2 Type-A: 3 ports ● 10-pin GPIO: 1 port ● Power input: 12V DC * This model does not include an operating system.

Features: ●CPU: Intel Core Processor (Series 3) ●Onboard Memory: Onboard LPDDR5 (up to 48GB) ●Onboard Storage: Onboard UFS (up to 256GB) ●LAN: 2.5GbE ×2 (Intel Ethernet Controller I226-IT) ●USB: USB 3.2 Type-A ×2, USB 3.2 Gen 2x2 Type-C ×1 ●GPIO: 40-pin GPIO ×1 ●Video Output: HDMI 2.1 (TMDS) ×2, DP 1.4a (via USB Type-C) ●Serial Port: RS-232/422/485 (10-pin header) ×2 ●Expansion Slots: M.2 2230 E-Key ×1, M.2 2280 M-Key ×1, M.2 2242 M-Key ×1 ●Security: TPM 2.0 ●Power Input: DC 12–24V input