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  6. Tandem Quadrupole Mass Spectrometer Xevo TQ Absolute

Tandem Quadrupole Mass Spectrometer Xevo TQ Absolute

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last updated:Dec 10, 2025

日本ウォーターズ(米国本社 Waters Corporation) 
日本ウォーターズ(米国本社 Waters Corporation) 
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Are you satisfied with just high sensitivity? - Ultra-high sensitivity LC-MS/MS that maintains stable operation for a long time and is easy to maintain.

Many people are struggling with systems that are prone to contamination and time-consuming maintenance. The Xevo TQ Absolute, known for its resistance to contamination thanks to the "ZSpray Ion Source," along with a new source shield, minimizes contamination of the ion source from sample matrices and salts in the mobile phase. It also allows for the removal of neutral molecules before the mass separation section (StepWave XS), concentrating ions for introduction into the mass separation section. This helps maintain the system in a "good condition" for a longer period, maximizing uptime. As a latest high-sensitivity model, it achieves higher sensitivity and lower quantitation limits. Additionally, it is more compact compared to conventional products, reducing power and gas consumption by about 50%, and also decreasing heat generation by approximately 50%. 【Features】 - Sensitivity to anionic compounds improved by up to 15 times (compared to previous products) - Ensures consistent robustness and reproducibility, maintaining performance and productivity over a longer period - Reduces electricity and gas consumption by about 50% compared to typical high-performance TQ mass spectrometers, with heat generation also reduced by about 50%

    Analytical Equipment and DevicesMass Spectrometer
Xevo_TQ_Absolute_Hero_White.jpg

Tandem Quadrupole Mass Spectrometer Xevo TQ Absolute

Xevo_TQ_Absolute_Hero_White.jpg
Xevo_TQ_Absolute_Hero_White.jpg XevoTQAbsolute_1.png XevoTQAbsolute_2.png XevoTQAbsolute_3.png XevoTQAbsolute_4.png XevoTQAbsolute_5.png
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basic information

Tandem (Triple) Quadrupole Mass Spectrometer (LC-MS/MS) Equipped with a ZSpray ion source resistant to contamination Adopts StepWave XS ion guide to improve transmission rates of unstable molecular species Ion source: Multi-mode ion source – Tool-free ESI/APCI/ESCi (standard), APCI, UniSpray, nanoFlow ESI, ASAP, APGC, DESI XS (optional)

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Applications/Examples of results

It can be used in various fields that require high-sensitivity quantification, such as bioanalysis of low molecular weight compounds, peptides, oligonucleotides, nitrosamines, PFAS, and pesticide analysis.

Detailed information

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Tandem Quadrupole Mass Spectrometer "Xevo TQ Absolute XR"

Tandem Quadrupole Mass Spectrometer "Xevo TQ Absolute XR"

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High-sensitivity tandem quadrupole mass spectrometer and analysis/analysis efficiency software.

Latest Trends in PFAS and Residual Pesticide Analysis in Food | Explanation of 700 Component Simultaneous Analysis Examples and Solutions for Improving Analysis Efficiency 12/8 [Live Webinar]

  • Seminar・Event

Amidst the growing demand for food safety and the strengthening of regulations, the need for analysis of food contaminants, including PFAS and pesticide residues, is expanding. As the diversity and lower concentrations of target components increase, there is a rising demand for analytical solutions that possess high sensitivity and robustness, capable of addressing complex food matrices, as well as efficient data analysis workflows. In this webinar, we will introduce the latest domestic and international trends surrounding food PFAS and pesticide residue analysis, and explain case studies of rapid simultaneous analysis of PFAS in food and 700 pesticide residues. Furthermore, we will present analytical solutions using high-sensitivity tandem quadrupole mass spectrometry and the latest software that streamlines data analysis and review. We aim to provide information that will help food manufacturers, contract analysis organizations, and research institutions involved in food safety analysis to improve analytical quality while enhancing operational efficiency. We look forward to your participation.

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How can we streamline the creation of separation methods for active pharmaceutical ingredients and nitrosamines? Nitrosamine Analysis Workshop [Tokyo, Osaka]

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We are currently holding a nitrosamine analysis observation event year-round at our Tokyo headquarters and Osaka branch showrooms. After confirming your preferred date, we will adjust the schedule and generally guide one group per day. Please send the following necessary information via the inquiry form on this page to apply: ■ Preferred venue (Tokyo or Osaka) ■ Preferred date - First choice ■ Preferred date - Second choice ■ Expected number of participants (up to 5 people) ■ Other requests By clicking [Send], you are deemed to have agreed to Waters' use and processing of the information provided on this site in accordance with Waters' Terms of Use and Privacy Notice. Terms of Use and Privacy Notice www.waters.com/legalandprivacy

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[Product Information] Consistently high robustness and reproducibility ensured! Tandem (Triple) Quadrupole Mass Spectrometer

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Xevo TQ Absolute is a robust LC-MS/MS that allows for easy quantification of challenging compounds with absolute sensitivity and reliability. ■ Application Notes Please contact us if you are interested. - High-sensitivity bioanalysis of low molecular weight pharmaceuticals - Bioanalysis of oligonucleotide drugs - High-sensitivity analysis of mutagenic boronic acids - Analysis of free testosterone in serum - Quantification of N-nitrosamines - Analysis of carboxy-THC in hair - Analysis of drugs in blood for toxicological investigations - Speciation analysis of gelatin - Analysis of anionic polar pesticides in food - Measurement of glyphosate, aminomethylphosphonic acid (AMPA), and glufosinate in drinking water - Measurement of chlorates, perchlorates, and bromates in food - Analysis of PFAS (method development and evaluation, in drinking water, aqueous matrices, soil and tissue, vegetables, fruits, baby food, animal products, etc.)

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日本ウォーターズ(米国本社

日本ウォーターズ(米国本社 Waters Corporation) 

Testing, Analysis and Measurement

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Waters Corporation, headquartered in Milford, Massachusetts, USA, has played a pioneering role as a specialized manufacturer of liquid chromatography since its establishment in 1958. Actively engaged in the development of new products and technologies, it has grown into an international group company that supplies not only high-performance liquid chromatography but also mass spectrometers (MS) and thermal analysis instruments. Waters Japan started operations in 1973 (Showa 48) as the Japanese base of Waters Corporation. Inheriting the corporate ethos of the U.S. headquarters, we have made "Customer Success" our mission and continue to provide innovative technologies and lab solutions.

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