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Fully synthetic (Chemically Defined) medium for the production of exosomes from human mesenchymal stem cells (MSCs)!

MSH-EV medium is a fully synthetic medium for the production of exosomes from human mesenchymal stem cells (MSCs). It has minimal contamination with microparticles, making exosome purification easier. It can support both expansion culture and exosome production in the same medium.

• Human cells

This is a serum-free medium that does not contain components derived from other species (xeno-free) and shows superior proliferation compared to 20% FBS supplemented αMEM medium.

This is a serum-free medium that does not contain components derived from non-human animal sources (xeno-free) (it does not contain bovine fetal serum (FBS) or human platelet lysate). The protein components consist solely of recombinant proteins expressed in microorganisms and human serum-derived albumin (pharmaceutical grade).

• Culture medium

Directly usable for mycoplasma detection tests based on each protocol!

Features of our Mycoplasma Detection Test Liquid Medium - Composition based on biological product standards - Demonstrates growth capability that meets the performance testing criteria of the Japanese Pharmacopoeia and biological product standards - Ready-to-use liquid medium that can be directly used for Mycoplasma detection tests based on various official standards - Usable for one year when stored at -20°C or below - Manufactured domestically

• Other cell research

Obtained a materials eligibility confirmation letter for regenerative medicine products from PMDA!

This product shows a higher proliferation support capability than the basic medium when supplemented with "UltraGRO" (AventaCell BioMedical product) and MSF-Supplement A.

• Culture medium

We can provide samples of human mesenchymal stem cell culture media (low serum, serum-free), exosome production media, etc.!

Shimadzu Diagnostics offers unique media developed in-house. Samples are available for all, so please feel free to contact us.

• Culture medium

Our culture medium products have obtained the Material Qualification Certificate for Regenerative Medicine Products!

The human mesenchymal stem cell proliferation medium MSF-BM and the serum-free culture medium DCO-K for immune cell therapy research have obtained the "Confirmation of Material Suitability for Regenerative Medicine Products" from the PMDA (Pharmaceuticals and Medical Devices Agency). Both media have been confirmed to comply with the standards for biological raw materials, allowing them to be used safely as raw materials for regenerative medicine products. For inquiries regarding the confirmation of material suitability for regenerative medicine products (PMDA): https://www.pmda.go.jp/review-services/f2f-pre/consultations/0035.html They are listed in the "List of Products that Have Obtained Confirmation" on the FIRM (Regenerative Medicine Innovation Forum) website. https://firm.or.jp/standard/support-s/1732/

• Culture medium

It is possible to achieve high sensitivity and rapid detection of viruses as described in the law concerning the assurance of safety in regenerative medicine and other related fields!

The gene detection kit VirFinder for virus denial testing can detect eight types of viruses listed in the law concerning the assurance of safety in regenerative medicine and other fields.

• Other Culture

Available as an alternative method to culture methods and DNA staining methods in mycoplasma detection tests!

"Myco Finder" is a solid-phase kit that simplifies the complex procedures of mycoplasma detection tests and allows for rapid testing. Since the reagents are solid-phased on the test strip, they only need to be dissolved during testing, which reduces the risk of contamination. Furthermore, with the adoption of high-speed amplification enzymes, the detection time is shorter than before, taking less than one hour from the start of amplification, allowing for results to be determined within a day. 【Features】 ■ No reagent preparation required ■ Detection time is within one hour from the start of amplification ■ High sensitivity ■ Can be stored in a cool place (2–8°C) *For more details, please refer to the catalog or feel free to contact us.

• Other purification and extraction

We will support you with all our strength! Please let us know your concerns regarding cell culture!

We would like to introduce our "Contract Manufacturing Service for Cell Culture Media." Manufacturing is possible in facilities where airborne particles and microorganisms are controlled. The raw materials used comply with biological origin material standards. Operations are managed based on the ISO 9001 quality management system. 【Features】 ■ Capable of producing both powdered and liquid media ■ Thorough manufacturing and quality control ■ We also offer analytical services as an option to provide suitable media - Simultaneous analysis of 95 components contained in the media - Effective when you want to know important indicators for managing cell culture processes and components that provide hints for media improvement *For more details, please refer to the PDF document or feel free to contact us.

• Culture medium

Important indicators for cell culture process management and tips for medium improvement! Simultaneous analysis of 95 components contained in the medium.

The "Cell Culture Medium Analysis Service" conducts component analysis using LCMS to examine changes in medium components before and after culture, as well as metabolites secreted by cells. This service is effective when you want to know about the components, providing data to achieve a suitable medium for the cells you use. We provide medium samples, so please feel free to contact us. 【Features】 ■ Simultaneous analysis of 95 components contained in the medium ■ Important indicators for managing cell culture processes and hints for medium improvement ■ Provision of medium samples ■ Custom manufacturing based on analysis results - GMP grade and research grade options available *For more details, please refer to the PDF materials or feel free to contact us.

• Culture medium

The time for celebration has come! The new production hall has started operations! While finishing work continues in other parts of the building, metal shavings are already being produced in the first machining center. Last Friday afternoon, employees and their families, along with companies involved in the construction, gathered to celebrate the achievements so far. Cold drinks, hot barbecue, and an ice cream stand were provided. During the celebration, many employees had the opportunity to tour the entire new building for the first time. Visitors were introduced to the new machines and improved logistics through guided tours of the production area. The new training room, the training center on the upper floor, and the latest conference room for customers were also unveiled. With this new building, Volkmann GmbH has secured an additional 4,500 square meters of production space. This expansion was very important, as the existing hall had already reached its limits due to the company's ongoing growth and increased production volume.

▶Issue: Before further processing the powder in the next stage (such as packaging machines), it is necessary to inspect for the presence of metal foreign objects using a metal detector. To achieve high sensitivity, the powder needs to be inspected through free fall, but due to low ceiling height and operational inconvenience, it is not possible to install the metal detector in the next stage. ▶Solution: The CEIA metal detector will be installed under a Volkmann vacuum conveyor and on a Volkmann mobile lift. The height-adjustable lift will allow the product discharge outlet of the metal detector to be adjusted to the appropriate height for the mobile container. Additionally, the vacuum conveyor can be lowered to a height that allows the mobile lift to pass through doors. The powder will be transported, for example, from an IBC container to the mobile lift and then to the metal detector via vacuum transfer. Metal foreign objects will be sorted and collected in a separate bottle. The inspected powder will be collected in a mobile container. Another vacuum conveyor is installed for the next stage, such as the packaging machine, from which the powder will be drawn from this container. Inspection and separation of metal parts can be conducted very close to the next stage, and it is also possible in more distant production areas.

The video shows that there is a tank at the bottom of the vacuum conveyor, and steam is constantly being released (in a simulated manner). If no measures are taken, the steam will enter the inside of the vacuum conveyor, condense into water droplets, and cause powder adhesion. Both our company and our customers have been troubled by such installations. This time, with the special module jointly developed with Minato Engineering Co., Ltd., we have succeeded in blocking the rising steam. From around the middle of the video, you can see that this function is turned on. You should be able to understand that the steam that was previously rising has disappeared. As a result, it has become possible to install equipment in a steam atmosphere, which was previously difficult to do, with peace of mind.

【Period: Ongoing until October 31, 2025】 For orders of 10 pieces or more: Dry T-shirt 1 piece @1,800 yen (tax included) Dry Polo Shirt 1 piece @2,300 yen (tax included) (Includes garment and one print location) For sizes 3L and above, an additional 550 yen An additional 550 yen for each additional print location Design and data production fees are required separately. (No fee if submitting complete data) We accept orders for various purposes such as events, teams, goods, souvenirs, and gifts, from one piece to mass production. We also have many other garments not listed. Please feel free to inquire.

September 1st to October 31st For events, exhibitions, and store promotions! A useful tote bag that makes a great gift Would you like to create a popular tote bag for promotional goods? We offer three convenient sizes. For more details, please contact us.