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  1. Home
  2. Testing, Analysis and Measurement
  3. TA Instruments Japan (TAInstruments)
  4. April Online LIVE Seminar! ~Protein Analysis Seminar~
SEMINAR_EVENT
  • Apr 12, 2023
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Apr 12, 2023

April Online LIVE Seminar! ~Protein Analysis Seminar~

TA Instruments Japan TA Instruments Japan (TAInstruments)
13:00~14:00 Examples of ITC Utilization - Useful Information Beyond Binding Strength - Masayuki Oda, Kyoto Prefectural University The Isothermal Titration Calorimeter (ITC) is a device that detects changes in heat associated with titration at a constant temperature, primarily used for analyzing molecular interactions. It provides information not only about binding strengths such as Ka and Kd of biomacromolecules like proteins, but also about binding ratios and thermodynamic quantities (ΔH, ΔS, etc.). This presentation will introduce how these pieces of information can be useful and applied, based on specific examples. 14:00~14:30 Introduction to Isothermal Titration Calorimetry (ITC) and Differential Scanning Calorimetry (DSC) for Biomacromolecules Minako Maeda, TA Instruments Application Department
Date and time Friday, Apr 21, 2023
01:00 PM ~ 02:30 PM
Please apply through the link.
Capital
Entry fee Free
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Related product

Discovery DSC.jpg

Differential Scanning Calorimeter Discovery DSC (Calorimeter)

How about one for the lab? Introducing the Discovery DSC series, the world's most outstanding and highly versatile differential scanning calorimeter.

TA Instruments continues to be the leading company in the world of DSC with innovative and outstanding technology. It provides reliable data and enhances workflow and productivity in laboratories. Material property analysis is essential at all stages of product design, manufacturing, processing, and application. Differential Scanning Calorimetry (DSC) is the most widely used thermal analysis instrument for evaluating the physical properties of a wide range of materials, including polymers, pharmaceuticals, food, biomaterials, organic compounds, inorganic compounds, and composites.

  • Analytical Equipment and Devices

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Collection of Thermal Analysis Case Studies for Protein Analysis (Calorimeter) ITC DSC

This is an introduction to protein analysis cases and related equipment by analysis specialists. This time, we will cover three devices: ITC, TAM, and NanoDSC!

Measurement capabilities offered by TA Instruments ☆ Thermal analysis / glass transition, crystallization, thermogravimetric analysis, curing reactions, expansion rate, thermal conductivity, shrinkage rate, effects of moisture, etc. ☆ Viscoelastic measurements (rheology, rheometers) / viscoelasticity, elastic modulus, viscosity, stress relaxation, creep, master curves, residual strain, molecular weight, molecular weight distribution, etc. ☆ Microcalorimetry / intermolecular interactions, crystallization, amorphousness, aggregation/precipitation, dispersibility, solubility, compatibility, wettability, stability, adsorption, etc. ☆ Fatigue testing / tensile strength, temperature dependence, viscoelasticity, elastic modulus, viscosity, stress relaxation, creep, master curves, residual strain, etc.

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1-DSC250_MicroCamera-Detail_jpg.jpg

Accessory for Differential Scanning Calorimeter (DSC) - Microscope Camera

Device accessories

The DSC measurements conducted with microscope accessories provide insights through multiple applications to better understand the properties and behaviors of materials. It is possible to capture images related to crystallization and melting transitions, flow of materials above the glass transition and melting points, phase transitions, and volume dimensional changes associated with evaporation and sublimation. Visual observation of color changes and other appearance alterations is used in combination with DSC data to gain a deeper understanding of the material being analyzed.

  • Color camera

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イプロス_サムネイル(タンパク質分析_ITC).jpg

Analysis case: Evaluation of substrate decomposition rate and inhibitor efficacy by ITC.

This is an introduction to a protein analysis case study by a specialist in analysis. This time, we evaluated the substrate degradation rate and the effects of inhibitors using ITC.

Measurement capabilities offered by TA Instruments ☆ Thermal analysis / glass transition, crystallization, thermogravimetric analysis, curing reactions, expansion rate, thermal conductivity, shrinkage rate, effects of moisture, etc. ☆ Viscoelastic measurement (rheology) / viscoelasticity, modulus of elasticity, viscosity, stress relaxation, creep, master curve, residual strain, molecular weight, molecular weight distribution, etc. ☆ Microcalorimetry / intermolecular interactions, crystallization, amorphousness, aggregation/precipitation, dispersibility, solubility, compatibility, wettability, stability, adsorption, etc. ☆ Fatigue testing / tensile strength, temperature dependence, viscoelasticity, modulus of elasticity, viscosity, stress relaxation, creep, master curve, residual strain, etc.

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イプロス_サムネイル(タンパク質分析_NanoDSC).jpg

Analysis case: Evaluation of protein denaturation temperature and Zn2+ effects using NanoDSC.

This is an introduction to a protein analysis case study by a specialist in analysis. This time, we evaluated the changes in denaturation temperature behavior with the addition of Zn2+ using NanoDSC.

Measurement capabilities offered by TA Instruments ☆ Thermal analysis / glass transition, crystallization, thermogravimetric analysis, curing reactions, expansion rate, thermal conductivity, shrinkage rate, effects of moisture, etc. ☆ Viscoelastic measurements (rheology) / viscoelasticity, elastic modulus, viscosity, stress relaxation, creep, master curve, residual strain, molecular weight, molecular weight distribution, etc. ☆ Microcalorimetry / intermolecular interactions, crystallization, amorphousness, aggregation/precipitation, dispersibility, solubility, compatibility, wettability, stability, adsorption, etc. ☆ Fatigue testing / tensile strength, temperature dependence, viscoelasticity, elastic modulus, viscosity, stress relaxation, creep, master curve, residual strain, etc.

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image_25.jpg

Isothermal Titration Calorimeter (Affinity ITC)

Provides high reliability! An excellent tool for measuring a wide range of molecular interactions.

The Isothermal Titration Calorimeter (ITC) is a device that detects the heat changes associated with titration at a constant temperature and is primarily used for analyzing molecular interactions. It measures the minute heat changes that occur when molecules bind to each other, allowing for the determination of binding ratio (n), binding constant (Ka), and the enthalpy change of binding (ΔH) from the resulting titration curve. Affinity ITC is an isothermal titration calorimeter that provides high sensitivity, high reproducibility, and advanced ITC technology in life science research environments. With AccuShot technology, it delivers precise amounts of titrant to the appropriate location, and the FlexSpin stirring function achieves efficient mixing and high sensitivity. The automatic cleaning function prevents contamination between samples. It offers the option of standard capacity (1.0 mL) or low capacity cells (190 µL), and a temperature-controlled auto-sampler for 96 wells is also available.

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Youtube Lecture Materials ~DSC Basic Edition 1~

This is the lecture material posted on YouTube ~DSC Basic Edition 1~. It is available for free download, so please feel free to make use of it.

Data Content This is a PDF version of the lecture materials from YouTube, converted for easier viewing. The video consists of a total of 12 pages and provides an easy-to-understand explanation for beginners about: - Principles - Analytical methods - Enthalpy relaxation (recovery) I think it might be difficult to understand with just the lecture materials, so please also refer to the YouTube videos below. YouTube TA Summary Site: https://www.youtube.com/channel/UCk3XzqRdsNQz1hJlqKrfujQ DSC Basics Part 1: https://www.youtube.com/watch?v=DbGpordpweg

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We will exhibit at the Kyushu Printing Information Industry Exhibition 2026.

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We will be exhibiting at the "Kyushu Printing Information Industry Exhibition 2026" held at the Fukuoka International Center. During the event, we will showcase various products. We invite all related parties to come together and visit us. 【Suppliers】 ・Laser-X

May 05, 2026

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Only 10 days until the Toyota Business Fair!

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This year, Toyota Kikan will exhibit at the Toyota Business Fair. We will introduce products that are useful for heatstroke prevention and more. Our top recommendation is SPACECOOL. Please feel free to visit our booth! SPACECOOL is an "eco-friendly cooling solution" essential for the future of our planet's environment! Be sure to check it out. Also, take a look at the basic knowledge for heat prevention in factories moving forward.

May 03, 2026

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6/11 Advancing Drawing Utilization DX with Barcodes - CADSUPER2026 Seminar

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In the operation of drawings, do you face challenges such as "taking too long to find," "uncertainty about whether it's the latest version," or "high likelihood of confirmation errors"? By utilizing CADSUPER's barcode function (optional), you can reliably connect drawings and information, allowing for a smooth advancement of DX in drawing utilization. In this seminar, we will introduce how using barcodes can change: - Drawing management and search - Confirmation and cross-checking tasks - Information collaboration with the field This content is recommended not only for existing users but also for those considering improving the efficiency of drawing operations and reducing errors.

May 01, 2026

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International Fire and Disaster Prevention Exhibition

Notice of Participation in the International Fire and Disaster Prevention Exhibition

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Daitō Shikō Co., Ltd. will be exhibiting at the "International Fire and Disaster Prevention Exhibition" held at Shirakawa Park in Nagoya City, Aichi Prefecture, from Thursday, May 28, 2026. At the exhibition venue, we plan to showcase goods that are perfect for fire prevention events and recruitment activities for members. If you are looking for SP tools, promotional items, or novelties, please be sure to visit our booth.

May 01, 2026

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[Seminar] Key Points for Consideration in Implementing CCS Projects

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[Speaker] Miho Ko Shimada, Partner Attorney, Mori Hamada & Matsumoto Law Firm, Foreign Law Joint Enterprise [Key Lecture Content] The movement towards the implementation of CCS, which is positioned as an essential technology for decarbonizing hard-to-abate industries, is gaining momentum in Japan. Among the "advanced CCS projects" selected for business commencement in the early 2030s, some pipeline projects have progressed to the exploratory drilling stage. For shipping transport projects, discussions are underway to create mechanisms for clustering CO2 sources and improving shipping transport efficiency. In this seminar, following the full enforcement of the CCS Business Act on May 22, we will organize the current state of the business environment related to CCS and examine the latest discussions at the Agency for Natural Resources and Energy and the Ministry of the Environment (based on information available at the time of the event) from a legal perspective as we consider the shape of CCS projects leading to Final Investment Decision (FID). [Lecture Items] 1. Current state of the business environment related to CCS 2. Overview of the CCS Business Act 3. Overview of the cost difference support system for CCS projects (pipelines) 4. Structural considerations through the CCS value chain 5. Q&A / Business card exchange

May 01, 2026

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  • 展示会出展等の販売促進に必要な費用を助成します! 最大300万円 助成率1/2以内 市場開拓助成事業 展示会等参加費・印刷物制作費・動画制作費 など 申請受付:令和8年 5/15(金)~5/29(金)
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