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  1. Home
  2. Testing, Analysis and Measurement
  3. TA Instruments Japan (TAInstruments)
  4. April Online LIVE Seminar! ~Protein Analysis Seminar~
SEMINAR_EVENT
  • Apr 12, 2023
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Apr 12, 2023

April Online LIVE Seminar! ~Protein Analysis Seminar~

TA Instruments Japan TA Instruments Japan (TAInstruments)
13:00~14:00 Examples of ITC Utilization - Useful Information Beyond Binding Strength - Masayuki Oda, Kyoto Prefectural University The Isothermal Titration Calorimeter (ITC) is a device that detects changes in heat associated with titration at a constant temperature, primarily used for analyzing molecular interactions. It provides information not only about binding strengths such as Ka and Kd of biomacromolecules like proteins, but also about binding ratios and thermodynamic quantities (ΔH, ΔS, etc.). This presentation will introduce how these pieces of information can be useful and applied, based on specific examples. 14:00~14:30 Introduction to Isothermal Titration Calorimetry (ITC) and Differential Scanning Calorimetry (DSC) for Biomacromolecules Minako Maeda, TA Instruments Application Department
Date and time Friday, Apr 21, 2023
01:00 PM ~ 02:30 PM
Please apply through the link.
Capital
Entry fee Free
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Discovery DSC.jpg

Differential Scanning Calorimeter Discovery DSC (Calorimeter)

How about one for the lab? Introducing the Discovery DSC series, the world's most outstanding and highly versatile differential scanning calorimeter.

TA Instruments continues to be the leading company in the world of DSC with innovative and outstanding technology. It provides reliable data and enhances workflow and productivity in laboratories. Material property analysis is essential at all stages of product design, manufacturing, processing, and application. Differential Scanning Calorimetry (DSC) is the most widely used thermal analysis instrument for evaluating the physical properties of a wide range of materials, including polymers, pharmaceuticals, food, biomaterials, organic compounds, inorganic compounds, and composites.

  • Analytical Equipment and Devices

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Collection of Thermal Analysis Case Studies for Protein Analysis (Calorimeter) ITC DSC

This is an introduction to protein analysis cases and related equipment by analysis specialists. This time, we will cover three devices: ITC, TAM, and NanoDSC!

Measurement capabilities offered by TA Instruments ☆ Thermal analysis / glass transition, crystallization, thermogravimetric analysis, curing reactions, expansion rate, thermal conductivity, shrinkage rate, effects of moisture, etc. ☆ Viscoelastic measurements (rheology, rheometers) / viscoelasticity, elastic modulus, viscosity, stress relaxation, creep, master curves, residual strain, molecular weight, molecular weight distribution, etc. ☆ Microcalorimetry / intermolecular interactions, crystallization, amorphousness, aggregation/precipitation, dispersibility, solubility, compatibility, wettability, stability, adsorption, etc. ☆ Fatigue testing / tensile strength, temperature dependence, viscoelasticity, elastic modulus, viscosity, stress relaxation, creep, master curves, residual strain, etc.

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Accessory for Differential Scanning Calorimeter (DSC) - Microscope Camera

Device accessories

The DSC measurements conducted with microscope accessories provide insights through multiple applications to better understand the properties and behaviors of materials. It is possible to capture images related to crystallization and melting transitions, flow of materials above the glass transition and melting points, phase transitions, and volume dimensional changes associated with evaporation and sublimation. Visual observation of color changes and other appearance alterations is used in combination with DSC data to gain a deeper understanding of the material being analyzed.

  • Color camera

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イプロス_サムネイル(タンパク質分析_ITC).jpg

Analysis case: Evaluation of substrate decomposition rate and inhibitor efficacy by ITC.

This is an introduction to a protein analysis case study by a specialist in analysis. This time, we evaluated the substrate degradation rate and the effects of inhibitors using ITC.

Measurement capabilities offered by TA Instruments ☆ Thermal analysis / glass transition, crystallization, thermogravimetric analysis, curing reactions, expansion rate, thermal conductivity, shrinkage rate, effects of moisture, etc. ☆ Viscoelastic measurement (rheology) / viscoelasticity, modulus of elasticity, viscosity, stress relaxation, creep, master curve, residual strain, molecular weight, molecular weight distribution, etc. ☆ Microcalorimetry / intermolecular interactions, crystallization, amorphousness, aggregation/precipitation, dispersibility, solubility, compatibility, wettability, stability, adsorption, etc. ☆ Fatigue testing / tensile strength, temperature dependence, viscoelasticity, modulus of elasticity, viscosity, stress relaxation, creep, master curve, residual strain, etc.

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イプロス_サムネイル(タンパク質分析_NanoDSC).jpg

Analysis case: Evaluation of protein denaturation temperature and Zn2+ effects using NanoDSC.

This is an introduction to a protein analysis case study by a specialist in analysis. This time, we evaluated the changes in denaturation temperature behavior with the addition of Zn2+ using NanoDSC.

Measurement capabilities offered by TA Instruments ☆ Thermal analysis / glass transition, crystallization, thermogravimetric analysis, curing reactions, expansion rate, thermal conductivity, shrinkage rate, effects of moisture, etc. ☆ Viscoelastic measurements (rheology) / viscoelasticity, elastic modulus, viscosity, stress relaxation, creep, master curve, residual strain, molecular weight, molecular weight distribution, etc. ☆ Microcalorimetry / intermolecular interactions, crystallization, amorphousness, aggregation/precipitation, dispersibility, solubility, compatibility, wettability, stability, adsorption, etc. ☆ Fatigue testing / tensile strength, temperature dependence, viscoelasticity, elastic modulus, viscosity, stress relaxation, creep, master curve, residual strain, etc.

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image_25.jpg

Isothermal Titration Calorimeter (Affinity ITC)

Provides high reliability! An excellent tool for measuring a wide range of molecular interactions.

The Isothermal Titration Calorimeter (ITC) is a device that detects the heat changes associated with titration at a constant temperature and is primarily used for analyzing molecular interactions. It measures the minute heat changes that occur when molecules bind to each other, allowing for the determination of binding ratio (n), binding constant (Ka), and the enthalpy change of binding (ΔH) from the resulting titration curve. Affinity ITC is an isothermal titration calorimeter that provides high sensitivity, high reproducibility, and advanced ITC technology in life science research environments. With AccuShot technology, it delivers precise amounts of titrant to the appropriate location, and the FlexSpin stirring function achieves efficient mixing and high sensitivity. The automatic cleaning function prevents contamination between samples. It offers the option of standard capacity (1.0 mL) or low capacity cells (190 µL), and a temperature-controlled auto-sampler for 96 wells is also available.

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Youtube Lecture Materials ~DSC Basic Edition 1~

This is the lecture material posted on YouTube ~DSC Basic Edition 1~. It is available for free download, so please feel free to make use of it.

Data Content This is a PDF version of the lecture materials from YouTube, converted for easier viewing. The video consists of a total of 12 pages and provides an easy-to-understand explanation for beginners about: - Principles - Analytical methods - Enthalpy relaxation (recovery) I think it might be difficult to understand with just the lecture materials, so please also refer to the YouTube videos below. YouTube TA Summary Site: https://www.youtube.com/channel/UCk3XzqRdsNQz1hJlqKrfujQ DSC Basics Part 1: https://www.youtube.com/watch?v=DbGpordpweg

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PIAB [Booth: West Hall 2 W2-32] will be exhibiting at iREX 2025 "2025 International Robot Exhibition"!

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[Exhibition Display] Demonstration of pineapple adhesion dynamics using collaborative robots Dynamic display using collaborative robots and tool changers for gripping Static display of a 5kg dual-sided gripper Comparison of ejector compressed air consumption Various suction pads Foam gripper, etc. We recommend visiting on the first or second day when you can view the exhibits with relative ease. *The third day (Friday) is expected to be very crowded. 【Gripper Sale Event】 We will be selling the following two products at a discounted price at the exhibition booth. Please inquire about the special prices at the venue. ■ 'KENOS Gripper KVGL.400.100, N214.FR6.S2' URL: https://www.youtube.com/watch?v=HsNRwrDtjW0 ■ 'Collaborative Robot Hand KCS.Q110.N301.110.FR6.SX422.V1.X.X' URL: https://www.youtube.com/watch?v=GFKg3blZzdQ These products are ideal not only for actual applications but also for use as test machines. How about taking this opportunity?

Dec 05, 2025

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[Seminar] New Trends and Prospects in the Defense Industry

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Venue attendance / Live streaming / Archive streaming (available for viewing multiple times over two weeks) [Instructor] Keiji Ono, Senior Researcher, National Defense Medical College, Ministry of Defense [Key Lecture Content] The defense industry has primarily focused on the manufacturing of heavy and large-scale products such as vehicles, vessels, aircraft, artillery, and ammunition. However, in recent years, global defense spending has increased, and the industrial structure has expanded into the realms of space, cyber, and electromagnetic waves. Japan is also facing a new phase in its history and current situation, shaped by post-war constraints, with the rise of IT and space-related startups shaking the framework centered around large corporations. Nevertheless, challenges such as organizational rigidity and slow decision-making remain, and the weaknesses pointed out in "The Essence of Failure" have not been overcome. This lecture will consider the new trends and prospects of the defense industry from both the possibilities and limitations, taking into account global trends and Japan's challenges. [Lecture Items] 1. Global defense spending / Defense industry 2. Global trends in the defense industry (West vs. China and Russia) 3. Japan's defense industry / Past and present 4. The rise of startup companies 5. Questions raised by "The Essence of Failure" 6. Q&A / Business card exchange

Dec 04, 2025

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[Seminar] Strategies for Entering the Sports Industry

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[Speaker] Arthur D. Little Japan, Inc. Partner Yu Hamada Principal Mikio Mizushima Consultant Daiki Masumoto [Key Lecture Content] The domestic sports industry is currently attracting attention as a growth area with both economic and social value. Supported by policy backgrounds, investments from both public and private sectors, including the development of stadiums and arenas, are becoming more active, transforming it into an attractive industry for companies considering new entries. What will be crucial moving forward is how to connect investments to sustainable monetization. Beyond mere support or branding, strategies that leverage sports as business assets are being called into question. In this lecture, we will consider these trends and redefine sports as a management asset that goes beyond mere entertainment or regional promotion, exploring the essentials for companies to enter and monetize from multiple perspectives. [Lecture Items] 1. Changes in the external environment surrounding the sports industry 2. New business opportunities created by "active sports" 3. Industrialization driven by "spectator sports" 4. Key points for companies to secure revenue opportunities when entering the market 5. Summary of today's discussion 6. Q&A / Business card exchange

Dec 04, 2025

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[Seminar] "Servant Leadership"

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[Instructor] Refresh Communications Communication Designer / Human Resource Development Consultant Yoshida Yukihiro [Key Lecture Content] In the VUCA era, it has become difficult to derive correct answers from existing experiences. It is precisely because we are in an era without clear answers that creative power and foresight are increasingly required. There is now a significant difference in results between leaders who possess these abilities and those who do not. Leaders with these qualities are characterized by their high ability to "engage members," and their leadership styles are "everyone leadership" and "servant leadership." In this course, we will focus on the overall picture of servant leadership and its 12 elements, presenting them in a way that can be immediately practiced. Following that, we will explain both skills and mindsets related to "subordinate-centered management," "psychological safety," "subordinate marketing," and "methods of encouragement," to enable subordinates to take initiative and perform at their best.

Dec 04, 2025

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[Free Seminar] Global ISO Certification as a Means of Corporate Governance - February 18, 2026 (Wednesday)

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Benefits of Global Certification for ISO 9001, 14001, 45001, 27001 and DNV's Approach ▶ Please apply using the "Details & Application" button below Purpose and Overview: Many Japanese companies are working on corporate governance to ensure management transparency, enhance corporate value, and respect the positions of stakeholders. However, challenges such as insufficient information disclosure, lack of communication with stakeholders, and delays in global risk management have also been pointed out. In this seminar, we will explain examples of European companies that actively utilize global ISO certification to achieve corporate governance, as well as DNV's approach. Target Participants: Individuals responsible for management planning, internal controls, management system oversight, and ISO administration. Points to be Gained from the Seminar: You will learn about case studies of utilizing existing ISO certifications. You will understand the benefits and considerations of global ISO certification.

Dec 04, 2025

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  • 【ホワイトペーパー進呈】機器の開発・製造前に考慮すべきライフサイクルコスト
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