How can we streamline the creation of separation methods for active pharmaceutical ingredients and nitrosamines? Nitrosamine Analysis Workshop [Tokyo, Osaka]

The self-inspection period will soon end. Are you ready for the upcoming operations?

The self-inspection regarding the contamination of nitrosamines in pharmaceuticals, notified by the Ministry of Health, Labour and Welfare in October 2021, has a deadline of August 1, 2025. By the deadline, it is necessary to measure the amount of nitrosamines contained in items at risk of contamination, and if the levels exceed the limit, risk reduction measures such as setting standard values must be taken. When setting standard values for nitrosamines, it is essential to use systems and analytical conditions that enable high-sensitivity analysis, and we also want the systems to have the robustness to withstand daily analysis. Waters supports high-sensitivity and robust analysis of nitrosamines with total solutions including high-sensitivity and robust mass spectrometers, LC systems and columns that achieve high separation, and informatics, as a specialized manufacturer of LC and mass spectrometry. By clicking [Submit], you are deemed to have agreed that Waters will use and process the information provided on this site in accordance with Waters' Terms of Use and Privacy Notice. Terms of Use and Privacy Notice www.waters.com/legalandprivacy

• Liquid Chromatograph
• Mass Spectrometer
• High Performance Liquid Chromatograph

Are you satisfied with just high sensitivity? - Ultra-high sensitivity LC-MS/MS that maintains stable operation for a long time and is easy to maintain.

Many people are struggling with systems that are prone to contamination and time-consuming maintenance. The Xevo TQ Absolute, known for its resistance to contamination thanks to the "ZSpray Ion Source," along with a new source shield, minimizes contamination of the ion source from sample matrices and salts in the mobile phase. It also allows for the removal of neutral molecules before the mass separation section (StepWave XS), concentrating ions for introduction into the mass separation section. This helps maintain the system in a "good condition" for a longer period, maximizing uptime. As a latest high-sensitivity model, it achieves higher sensitivity and lower quantitation limits. Additionally, it is more compact compared to conventional products, reducing power and gas consumption by about 50%, and also decreasing heat generation by approximately 50%. 【Features】 - Sensitivity to anionic compounds improved by up to 15 times (compared to previous products) - Ensures consistent robustness and reproducibility, maintaining performance and productivity over a longer period - Reduces electricity and gas consumption by about 50% compared to typical high-performance TQ mass spectrometers, with heat generation also reduced by about 50%

• Analytical Equipment and Devices
• Mass Spectrometer

Reliable characteristic analysis - A mass spectrometer that maximizes information about the analysis species.

By using the Xevo G3 QTof, you can maximize the information about the analysis species from samples, enhancing the reliability of results from detailed characterization to accurate quantification. It simplifies and expands the characterization and evaluation of properties, from unstable low molecular weight compounds to complex biopharmaceuticals. By updating the design of the ion optical system and incorporating core technologies that achieve comprehensive quantification capabilities, consistent robustness and performance have been achieved. 【Features】 - Improved permeability of unstable low molecular compounds maximizes coverage of analysis species - Enhanced quantitativeness and expanded dynamic range within and between spectra enable optimal comprehensive quantification/qualitative analysis for screening and target applications - Improvements in the ion optical system lead to a more reliable and robust system - Achieves high levels of accuracy and reproducibility

• Analytical Equipment and Devices

Solving non-specific sample adsorption! Improved peak shape and sensitivity with new technology, featuring low adsorption and bio-inert LC with excellent reproducibility and durability.

The ACQUITY Premier system incorporates the new MaxPeak High Performance Surfaces (HPS) technology, which effectively reduces sample loss due to nonspecific adsorption caused by interactions with metals, while providing the following benefits: ■ Ideal for the analysis of organic acids, organophosphates, oligonucleotides, peptides, glycoproteins, phospholipids, veterinary drugs, chelating agents, and more. ■ Improved sensitivity and reduced risk of peak omission. ■ Elimination of column and system passivation and conditioning, saving time and costs. ■ Enhanced reproducibility and reliability of results. A variety of low-adsorption columns featuring MaxPeak High Performance Surfaces (HPS) technology are also available. When used in combination with the system, they enable more reliable analyses. *We also offer online briefings and demonstrations, so please feel free to contact us.

• Analytical Equipment and Devices

We will introduce the implementation results of the sensor technology developed by the Hotron Group, which has been cultivated over more than half a century, through customer case studies. In addition to automatic door sensors, we also offer a wide range of vehicle detection sensors and nursing/care sensors. Many implementation examples are also presented, so please take a look at the case study page.

Parking space management refers to the real-time display of parking availability and the management of efficient use of parking spaces. By utilizing Hotron's sensors, drivers can quickly discover available parking spaces, enabling efficient parking lot operations. For large parking lots, we recommend the "Floor Management Method" and "Block Management Method," which focus on cost reduction. Sensors are installed at regular intervals to count and manage the number of passing vehicles. This method offers the advantages of easy installation and low costs. 【Target Products】 - Vehicle Count Sensor CCS2 - Ultrasonic Sensor HM-UX2/UW2 For smaller facilities, we recommend the "Parking Space Management Method," where sensors are installed in each parking space to display availability with high accuracy. By providing reliable occupancy information, this method helps reduce unnecessary entry of new vehicles and ensures safe parking lot operations. 【Target Products】 - Occupancy Detection Sensor HM-UX2/UW2 - Occupancy/Pass Detection Sensor HM-LC6 - Occupancy Detection Sensor HM-LC7/LC7-FLS - Occupancy/Pass Detection Sensor HM-S6 - Occupancy Detection Sensor HM-S8

To everyone who wants to develop new chocolate products without worrying about the soaring cocoa prices. Cluster products that enhance texture, aroma, and appearance while reducing the amount of chocolate used, adding value to the products. We offer three types of cluster manufacturing equipment that can be selected according to your application and goals. We can propose the most suitable equipment based on your objectives. 1) K&S / GFT | One-bite snack & cereal bar molding machine 2) Trkino / Nuts-i | High-end depositor that can deposit ingredients like nuts together 3) Wolf / PORTIOMAT – CLUSTER FORMING | Cluster former equipped with innovative technology

Los Angeles (California, USA) / Paris (France), May 4, 2026 - (JCN Newswire) - Pacific Avenue Capital Partners, a global private equity firm focused on corporate carve-outs and other complex transactions in the mid-market, announced today that its affiliate has entered into exclusive negotiations to acquire ESE World (hereinafter "ESE") from Amcor, one of the world's leading packaging companies. With the support of Pacific Avenue, ESE will focus on responding to customer needs while implementing multiple growth initiatives related to operational improvements, regional expansion, and strategic add-on acquisitions. Pacific Avenue plans to work closely with ESE's existing management team to drive these initiatives and accelerate the company's next phase of growth.

Fukuda Co., Ltd. has been pursuing leak detection for 60 years and is committed to advancing the future of leak testing. 【 Supporting Various Leak Tests: Air Leak Test / Gas Leak Test (Hydrogen Gas, Helium Gas) 】 We develop, manufacture, and sell leak testing equipment to inspect airtightness and sealing properties. We will propose the appropriate testers and devices for each inspection target. 【 Target Industries and Examples of Inspection Targets 】 - Automotive Industry: Engines, FC components, valves and piping, various parts - Electronic Components Industry: Smartphones, keyless switches, various small sensors - Pharmaceuticals / Food / Cosmetics Industry: Bottle containers, syringes, vials, eye drop containers, pillow packaging, PTP packaging We will propose the most suitable leak testers for each industry. 【 ISO Certification 】JIS Q 9001:2015 (ISO 9001:2015)