High-resolution mass spectrometer (LC-QTof) Xevo G3 QTof

We are currently holding a nitrosamine analysis observation event year-round at our Tokyo headquarters and Osaka branch showrooms. After confirming your preferred date, we will adjust the schedule and generally guide one group per day. Please send the following necessary information via the inquiry form on this page to apply: ■ Preferred venue (Tokyo or Osaka) ■ Preferred date - First choice ■ Preferred date - Second choice ■ Expected number of participants (up to 5 people) ■ Other requests By clicking [Send], you are deemed to have agreed to Waters' use and processing of the information provided on this site in accordance with Waters' Terms of Use and Privacy Notice. Terms of Use and Privacy Notice www.waters.com/legalandprivacy

What is an efficient separation method development approach for the analysis of nitrosamines? Nitrosamines in pharmaceuticals are a health risk even at extremely low concentrations and are subject to regulation in various countries. In Japan, the Ministry of Health, Labour and Welfare issued a notification in 2021, mandating that measures must be taken by August 1, 2025. As ongoing quality testing is expected, the establishment of a reliable analytical system is required. However, nitrosamines are impurities that require trace-level and highly sensitive detection, and the establishment of advanced separation techniques (separation methods) that are not influenced by the active ingredients or excipients is key. In this seminar, we will explain: - Key points for global regulatory compliance - Development approaches for separation methods essential for trace impurity analysis - Features of devices equipped with ZSpray structures that excel in maintainability and contamination resistance We will provide a practical demonstration. If you are considering the introduction or update of equipment, or if you have challenges with the sensitivity and accuracy of impurity analysis, please join us. 【Title】 Nitrosamine Analysis Observation Meeting: How to streamline the creation of separation methods for active pharmaceutical ingredients and nitrosamines? ~Introducing approaches for developing separation conditions~