Screening Calculation Workshop Using Machine Learning MTS Method with myPresto

Workshop on drug discovery calculations using supercomputers

We will conduct screening calculations for drug candidate compounds using the free drug discovery software myPresto.

• Technical Seminar

In silico screening and MD can be easily performed.

MF myPresto is a graphical user interface (GUI) software developed for the molecular simulation system myPresto, which supports drug development and was developed as part of a commissioned project by the Ministry of Economy, Trade and Industry, NEDO, and AMED. By using MF myPresto, molecular dynamics (MD) calculations, docking simulations, and in silico screening can be easily performed with myPresto.

• others

Drug design software with high-speed screening calculation capabilities.

MolDesk Screening is a GUI program developed by Information Mathematical Bio Co., Ltd. to efficiently utilize the molecular simulation system myPresto for drug discovery support. MyPresto was developed as part of a commissioned project from the Ministry of Economy, Trade and Industry, NEDO, and AMED. In MolDesk Screening ver.1.1, virtual screening of 2 million compounds can be performed on a PC (8 parallel) in half a day to 2 days. During virtual screening, four different ranking methods—docking score order, MTS method, machine learning MTS method, and machine learning DSI method—can be used selectively depending on the situation. 【Features】 ■ Fast screening calculations executed in thread parallelism ■ Easy confirmation of docking poses for top compounds ■ High-precision pocket exploration using myPresto's Molsite ■ Ability to substitute amino acids in proteins with other amino acids (supports 40 types including chemically modified amino acids) ■ High-speed MD parallel calculations using MPI/GPU (NVIDIA CUDA) For more details, please refer to the catalog or feel free to contact us.

• Other information systems
• others

Support to quickly initiate experiments for the exploration of candidate drug compounds.

Bio Modeling Research Co., Ltd. supports experimental research in the life sciences using IT technology. We assist in quickly starting experiments for drug candidate compound discovery, from docking calculations to the initiation of experiments. Bio Modeling Research utilizes the FOCUS supercomputer operated by the Computational Science Promotion Foundation and the HGC supercomputer at the University of Tokyo's Institute of Medical Science, enabling relatively inexpensive large-scale computations using over 500 cores. 【Features】 - Primarily uses myPresto for in silico screening calculations - Sales and support for the use of MF myPresto developed by Fearlux Co., Ltd. - Sales and support for the use of MolDesk developed by Information Mathematical Biology Co., Ltd. - Bio Modeling Research is a supporting member of the Computational Science Promotion Foundation. For more details, please contact us or view the information from "PDF Download."

• Contract Analysis
• Other information systems
• Other services

We will be exhibiting at the "12th Conference of the Advanced Power Semiconductor Subcommittee" held at the Toyama International Conference Center. We will be introducing our latest analysis technology services, so please stop by! We sincerely look forward to your visit.

We will explain the thermal design of power ICs (LDO / DCDC) under the title "Thermal Design of Power ICs (LDO / DCDC)," which is crucial when designing power blocks. The explanation will cover fundamental concepts as well as delve into topics such as PCB layout and design. This webinar is recommended for those currently involved in PCB design and product development. ● Target Audience - Individuals involved in the design, technology, manufacturing, and quality control of various electrical products and power blocks - Those facing challenges or issues related to power ICs that they wish to resolve ● Title Thermal Design of Power ICs (LDO / DCDC) ● Agenda 1. Impact of IC Heat Generation - Definition of Thermal Resistance, etc. 2. Thermal Design of LDO and DCDC - How to Determine Tj 3. Losses, Heat Generation, and Thermal Shutdown of LDO 4. Losses in DCDC 5. Case Studies 6. PCB Design 7. Thermal Design Support 8. Q&A We look forward to your participation.

[Speaker] Tatsu Nagai, Representative Employee of Go2Marketing (Co.) / Host of VSI AV Portal [Lecture Topics] 1. Autonomous Robot Taxis 2. Surveillance Robot Taxis 3. Remote-Controlled Robot Taxis 4. Progress of Global Regulations on Autonomous Driving 5. Evolution of AI Technology in Autonomous Driving 6. Summary 7. Q&A

[Key Lecture Content] 1. The Significance of International Standardization and Global Strategies Utilizing It (Tokyo Institute of Technology) National Institute of Advanced Industrial Science and Technology, Senior Researcher Chairman of IEC TC85 Domestic Committee, Mr. Tatsuji Yamada In June of this year, the Cabinet Office's Intellectual Property Strategy Headquarters decided on a "New International Standard Strategy." This aims to lead solutions to important domestic and international issues through international standards and to create new markets. Here, we will reaffirm the significance of international standardization, introduce examples of global strategies utilizing it, and also discuss international standardization in NILM. 2. Global Strategies Leveraging International Standardization by Venture Companies - The Case of Infomatis Infomatis Inc., President and CEO, Mr. Taro Tadano In creating new businesses in the global market, international standardization can be an effective strategic tool for Japanese ventures. In this presentation, we will introduce the insights and practical examples of international standardization utilized by Infomatis, cultivated in large corporations, and consider its potential and practical significance.

[Key Lecture Content] 1. Domestic and International Trends Surrounding CDR Masako Tanaka, Senior Researcher, Decarbonization Innovation Group, GX Headquarters, Energy and Sustainability Division, Mitsubishi Research Institute, Inc. 1. Overview of CDR 2. International Trends 3. Domestic Trends 4. Challenges for Dissemination 5. Future Outlook and Recommendations 6. Q&A / Business Card Exchange 2. Types of Risks in the Carbon Credit Field and Corresponding Measures Tomofumi Shibata, Unit Leader, GX Department, Market Strategy Division, Tokio Marine & Nichido Fire Insurance Co., Ltd. 1. Opportunities and Risks Associated with Carbon Credits 2. Classification of Risks Considered at Each Stage and Possible Countermeasures 3. Q&A / Business Card Exchange 3. Mitsubishi Corporation's Initiatives in the CDR Field and Insights Gained Kei Endo, Manager, Carbon Management Department, Next Generation Energy Headquarters, Global Environment & Energy Group, Mitsubishi Corporation 1. Our Initiatives in the CDR Field 2. Insights Gained from Previous Activities 3. Introduction to the Japan CDR Council 4. Q&A / Business Card Exchange