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  1. Home
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  3. TA Instruments Japan (TAInstruments)
  4. July Online LIVE Seminar! ~Protein Analysis Seminar~
SEMINAR_EVENT
  • Jun 08, 2022
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Jun 08, 2022

July Online LIVE Seminar! ~Protein Analysis Seminar~

TA Instruments Japan TA Instruments Japan (TAInstruments)
13:00~14:00 Analysis of the interaction between sleep substance-synthesizing enzyme and ligand using isothermal titration calorimetry Shigeru Shimamoto, Lecturer, Department of Life Science, College of Science and Engineering, Kinki University Isothermal titration calorimetry (ITC) has the significant advantage of detecting molecular interactions in a form that is closer to the state present in vivo, without the need for chemical modifications, immobilization, or detection probes. Furthermore, it is a method that provides nearly complete thermodynamic parameters related to the interactions. Here, I will introduce the analysis of the interaction between lipocalin-type prostaglandin D synthase (L-PGDS), which acts as a sleep substance-synthesizing enzyme in the mammalian brain, and its ligand, prostaglandin (PG), using ITC, and discuss the elucidation of the enzyme reaction mechanism in conjunction with structural information. 14:00~14:30 Introduction to isothermal titration calorimetry (ITC) and differential scanning calorimetry (DSC) for biomacromolecules Minako Maeda, Applications Department, TA Instruments
Date and time Friday, Jul 22, 2022
01:00 PM ~ 02:30 PM
Please apply through the link.
Capital
Entry fee Free Thank you very much for your participation.
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Discovery DSC.jpg

Differential Scanning Calorimeter Discovery DSC (Calorimeter)

How about one for the lab? Introducing the Discovery DSC series, the world's most outstanding and highly versatile differential scanning calorimeter.

TA Instruments continues to be the leading company in the world of DSC with innovative and outstanding technology. It provides reliable data and enhances workflow and productivity in laboratories. Material property analysis is essential at all stages of product design, manufacturing, processing, and application. Differential Scanning Calorimetry (DSC) is the most widely used thermal analysis instrument for evaluating the physical properties of a wide range of materials, including polymers, pharmaceuticals, food, biomaterials, organic compounds, inorganic compounds, and composites.

  • Analytical Equipment and Devices

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Collection of Thermal Analysis Case Studies for Protein Analysis (Calorimeter) ITC DSC

This is an introduction to protein analysis cases and related equipment by analysis specialists. This time, we will cover three devices: ITC, TAM, and NanoDSC!

Measurement capabilities offered by TA Instruments ☆ Thermal analysis / glass transition, crystallization, thermogravimetric analysis, curing reactions, expansion rate, thermal conductivity, shrinkage rate, effects of moisture, etc. ☆ Viscoelastic measurements (rheology, rheometers) / viscoelasticity, elastic modulus, viscosity, stress relaxation, creep, master curves, residual strain, molecular weight, molecular weight distribution, etc. ☆ Microcalorimetry / intermolecular interactions, crystallization, amorphousness, aggregation/precipitation, dispersibility, solubility, compatibility, wettability, stability, adsorption, etc. ☆ Fatigue testing / tensile strength, temperature dependence, viscoelasticity, elastic modulus, viscosity, stress relaxation, creep, master curves, residual strain, etc.

  • Analytical Equipment and Devices

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Accessory for Differential Scanning Calorimeter (DSC) - Microscope Camera

Device accessories

The DSC measurements conducted with microscope accessories provide insights through multiple applications to better understand the properties and behaviors of materials. It is possible to capture images related to crystallization and melting transitions, flow of materials above the glass transition and melting points, phase transitions, and volume dimensional changes associated with evaporation and sublimation. Visual observation of color changes and other appearance alterations is used in combination with DSC data to gain a deeper understanding of the material being analyzed.

  • Color camera

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Analysis case: Evaluation of substrate decomposition rate and inhibitor efficacy by ITC.

This is an introduction to a protein analysis case study by a specialist in analysis. This time, we evaluated the substrate degradation rate and the effects of inhibitors using ITC.

Measurement capabilities offered by TA Instruments ☆ Thermal analysis / glass transition, crystallization, thermogravimetric analysis, curing reactions, expansion rate, thermal conductivity, shrinkage rate, effects of moisture, etc. ☆ Viscoelastic measurement (rheology) / viscoelasticity, modulus of elasticity, viscosity, stress relaxation, creep, master curve, residual strain, molecular weight, molecular weight distribution, etc. ☆ Microcalorimetry / intermolecular interactions, crystallization, amorphousness, aggregation/precipitation, dispersibility, solubility, compatibility, wettability, stability, adsorption, etc. ☆ Fatigue testing / tensile strength, temperature dependence, viscoelasticity, modulus of elasticity, viscosity, stress relaxation, creep, master curve, residual strain, etc.

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イプロス_サムネイル(タンパク質分析_NanoDSC).jpg

Analysis case: Evaluation of protein denaturation temperature and Zn2+ effects using NanoDSC.

This is an introduction to a protein analysis case study by a specialist in analysis. This time, we evaluated the changes in denaturation temperature behavior with the addition of Zn2+ using NanoDSC.

Measurement capabilities offered by TA Instruments ☆ Thermal analysis / glass transition, crystallization, thermogravimetric analysis, curing reactions, expansion rate, thermal conductivity, shrinkage rate, effects of moisture, etc. ☆ Viscoelastic measurements (rheology) / viscoelasticity, elastic modulus, viscosity, stress relaxation, creep, master curve, residual strain, molecular weight, molecular weight distribution, etc. ☆ Microcalorimetry / intermolecular interactions, crystallization, amorphousness, aggregation/precipitation, dispersibility, solubility, compatibility, wettability, stability, adsorption, etc. ☆ Fatigue testing / tensile strength, temperature dependence, viscoelasticity, elastic modulus, viscosity, stress relaxation, creep, master curve, residual strain, etc.

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image_25.jpg

Isothermal Titration Calorimeter (Affinity ITC)

Provides high reliability! An excellent tool for measuring a wide range of molecular interactions.

The Isothermal Titration Calorimeter (ITC) is a device that detects the heat changes associated with titration at a constant temperature and is primarily used for analyzing molecular interactions. It measures the minute heat changes that occur when molecules bind to each other, allowing for the determination of binding ratio (n), binding constant (Ka), and the enthalpy change of binding (ΔH) from the resulting titration curve. Affinity ITC is an isothermal titration calorimeter that provides high sensitivity, high reproducibility, and advanced ITC technology in life science research environments. With AccuShot technology, it delivers precise amounts of titrant to the appropriate location, and the FlexSpin stirring function achieves efficient mixing and high sensitivity. The automatic cleaning function prevents contamination between samples. It offers the option of standard capacity (1.0 mL) or low capacity cells (190 µL), and a temperature-controlled auto-sampler for 96 wells is also available.

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Youtube Lecture Materials ~DSC Basic Edition 1~

This is the lecture material posted on YouTube ~DSC Basic Edition 1~. It is available for free download, so please feel free to make use of it.

Data Content This is a PDF version of the lecture materials from YouTube, converted for easier viewing. The video consists of a total of 12 pages and provides an easy-to-understand explanation for beginners about: - Principles - Analytical methods - Enthalpy relaxation (recovery) I think it might be difficult to understand with just the lecture materials, so please also refer to the YouTube videos below. YouTube TA Summary Site: https://www.youtube.com/channel/UCk3XzqRdsNQz1hJlqKrfujQ DSC Basics Part 1: https://www.youtube.com/watch?v=DbGpordpweg

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Notice of Participation in the 'New Functional Materials Exhibition 2025' (Teijin/Teijin Frontier) from January 29 (Wednesday) to January 31 (Friday), 2025.

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Our company will be exhibiting at the "New Functional Materials Exhibition 2025," which will be held at Tokyo Big Sight starting from January 29, 2025 (Wednesday). We would be delighted if you could visit us at the venue if you have the time. ┏━━━━━━━━━━━━━━━━━━━━━━━━━━ ■ Exhibition Information Details ┗━━━━━━━━━━━━━━━━━━━━━━━━━━ Exhibition Name: "New Functional Materials Exhibition 2025" Exhibition Venue: Tokyo Big Sight, East Hall 5 Booth Number: 5W-23 Teijin/Teijin Frontier Co., Ltd. Event Dates: January 29 (Wednesday) to 31 (Friday), 2025, 10:00 AM to 5:00 PM ■ About the Exhibited Products At this exhibition, we will broadly introduce our newly developed high-performance non-woven fabrics. We will showcase ultra-thin and ultra-light non-woven fabrics, newly developed marine biodegradable PLA, carbon paper, porous high-performance membrane "MiraimⓇ," graphene heat dissipation paint that enhances heat dissipation effects and lowers the temperature of objects, heat dissipation and electromagnetic wave absorption sheets, water treatment technology, oil-water separation technology, and various other new high-performance products. All of our exhibition staff sincerely look forward to your visit.

Jan 19, 2026

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Notice of Participation in the 1st [Nagoya] High-Performance Plastics Exhibition - PLASTIC JAPAN -

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We will be exhibiting at the "1st [Nagoya] High-Performance Plastics Exhibition -PLASTIC JAPAN-" held at Port Messe Nagoya. We will introduce samples and characteristics of our carbon nanofibers blended with various resins. The conductive carbon nanofiber (high dispersion) ALP-NK1 (550W/mK) has also been added to our product lineup, and we will propose materials tailored to customer needs, starting with heat dissipation applications. Additionally, we will showcase extruded round bars of PEEK blended with carbon nanofibers and their processed products, as well as doctor blades designed for battery materials. As a business model for our nanomaterial business, we offer sales of CNF powder and prototype sales of resin blends (pellets and liquid resins) according to customer requests. Furthermore, we will introduce various silicon materials, including silicon monoxide, which is gaining attention as electrode materials for high-capacity lithium-ion secondary batteries, as well as magnesium balls. We welcome various requests regarding compounds, alloys, purity, particle size, and shapes, so please feel free to stop by our booth for consultation. We sincerely look forward to your visit.

Jan 19, 2026

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Notice of Participation in the Fukushima Tech Create 2026 Results Presentation Event from January 29 (Thursday) to January 30 (Friday), 2026.

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Our company will be exhibiting at the "Fukushima Tech Create 2026 Results Presentation" held in Okuma Town, Fukushima Prefecture. At this event, promising startups aiming for entrepreneurship and technological development in areas such as Hamadori, Fukushima Prefecture, will present their research and business results. ★ Participating Industry Fields Decommissioning / Robotics and Drones / Energy, Environment, and Recycling Agriculture, Forestry, and Fisheries / Medical-related / Aerospace On the 29th (Thursday), a talk event featuring notable figures and local entrepreneurs will also be held. A collection of attention-grabbing technologies that will shape the future will be gathered, so please feel free to stop by the IIDA booth when you visit. [Limited Company Iida Seisakusho Fukushima No. 2 Factory] 〒969-1204 21-2 Mizukami, Nukazawa, Motomiya City, Fukushima Prefecture TEL: 0243-64-2320 FAX: 0243-64-2571

Jan 19, 2026

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■Notice of the "2024 Attack Fair in Konan"!■ 【October 9, 2024 (Wednesday) to October 10, 2024 (Thursday)】

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Nitto Kohki will hold the "2024 Attack Fair in Konan" at the Aoisui Hall for two days from October 9 (Wednesday) to October 10 (Thursday), 2024. The Attack Fair is an exhibition where you can actually "see, touch, and operate" Nitto Kohki's products. Additionally, there will be wonderful souvenirs for attendees and many fun activities prepared. We look forward to welcoming everyone!

Jan 16, 2026

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■Notice of the "2025 Attack Fair in Meiko"!■ 【July 23, 2025 (Wednesday) - July 24, 2025 (Thursday)】

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Nitto Kohki will hold the "2025 Attack Fair in Meiko" for two days from July 23 (Wednesday) to July 24 (Thursday), 2025, at the "Kowa Seminar Plaza 2F Training Room NO.12 (inside Kowa Sports Land)." The Attack Fair is an exhibition where you can actually "see, touch, and operate" Nitto Kohki's products. Additionally, there will be wonderful souvenirs for attendees and many fun activities planned. We look forward to welcoming everyone!

Jan 16, 2026

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  • 首都圏最大級の工業技術・製品の総合見本市 テクニカルショウヨコハマ2026 第47回 工業技術見本市 時代をひらく新たな技術 2026年2/4(水)・5(木)・6(金) 10:00-17:00 来場者募集中
  • 展示会に出展したいけど準備が大変 展示会の情報をまとめて知りたい そんな展示会のお悩み 展サポ(R)で解決! ブース装飾で実績豊富 展示会情報を多数掲載 出展前~後まで支援
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