We will introduce the scoring of an atopic dermatitis model using BioSta AD.
In the atopic dermatitis model using BioSta AD, after destroying the skin barrier with 4% SDS, the product is applied to the dorsal and auricular areas of the mice twice a week at a dosage of 100 mg/mouse. The induction period is approximately 3 weeks (totaling 6 applications). Ultimately, a total of 600 mg of the product will be applied. In this model, symptoms begin to appear from weeks 1 to 2 after application, with an incidence rate of about 80% observed by weeks 3 to 4. 【Scoring】 [Redness and bleeding (observing redness and bleeding symptoms on the back)] ○0: Asymptomatic; no redness or bleeding symptoms observed on the back ○1: Mild; localized redness observed on the back, with no bleeding associated with continuous scratching ○2: Moderate; scattered redness observed on the back, with no bleeding associated with continuous scratching ○3: Severe; widespread redness observed on the back, with bleeding associated with continuous scratching For more details, please contact us or download the catalog.
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**Scoring** [Crust formation and dryness (observing crust formation and dryness symptoms on the back)] ○0: Asymptomatic; no crust formation or dryness symptoms on the back ○1: Mild; localized crust formation observed on the back, with slight whitening of the skin and minimal desquamation ○2: Moderate; scattered crust formation observed on the back, or clear desquamation ○3: Severe; widespread crust formation on the back, or clear desquamation [Edema (qualitatively observing edema of the auricle)] ○0: Asymptomatic; no thickness observed in either auricle ○1: Mild; slight thickness observed in one of the auricles ○2: Moderate; clear thickness and tension observed in either auricle ○3: Severe; clear thickness, tension, and curvature observed in either auricle, with hardness felt upon touch ● For more details, please contact us or download the catalog.
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In modern society, allergies are a very common illness. Many of you may have family or friends who are struggling with this condition. The causes of allergies are diverse, including dust mites, house dust, pollen, and food, among others. All of these are inseparable from everyday life, and it is impossible to live normally while isolating oneself from these allergens. While medication is the mainstream treatment for allergies, it is also important to prevent symptoms by improving the living environment to reduce the entry of allergens into the body. It is crucial to suppress allergies comfortably and safely. To achieve this, it is necessary to utilize a wide range of technologies. BioSta Inc. (bio: biotechnology, stir: to stir/mix) was named with the intention of tackling this challenge by mixing various technologies and products.