Support for safety testing from the screening stage to entering clinical trials!
Inari Research supports safety testing from the screening phase to the entry into clinical trials (clinical studies). In addition to core battery tests based on guidelines, we can propose various follow-up tests and supplementary safety pharmacology tests. With the testing techniques and know-how cultivated over many years, we will propose appropriate test designs. 【Gastrointestinal System Examples】 ■ Effects on gastrointestinal mucosa (rats) - Search for effects on gastrointestinal mucosa through macroscopic observation or pathological examination. ■ Effects on gastric secretion (rats, dogs, monkeys) - Search for effects on gastric secretion using pyloric ligation or gastric lavage methods. ■ Effects on intestinal secretion (rats) - Search for effects on intestinal secretion by measuring the moisture content of the intestines. ■ Effects on bile secretion (rats) ■ Vomiting observation (dogs, monkeys) - Observation of the frequency of vomiting and the contents of vomit. *For more details, please refer to the PDF materials or feel free to contact us.
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The study will be conducted at a facility that is GLP-compliant and has obtained certification from AAALAC International (the Association for Assessment and Accreditation of Laboratory Animal Care International). A series of non-clinical study sets, including genotoxicity tests and safety pharmacology tests necessary to enter clinical trials (Phase I), can be completed with the final report prepared within six months. *For more details, please refer to the PDF materials or feel free to contact us.
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For more details, please refer to the PDF document or feel free to contact us.
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Our company is located in the nature-rich city of Ina, Nagano Prefecture, surrounded by two Alps, and has been serving our customers as a non-clinical trial contract research organization (CRO) for 50 years. Since 2022, we have become a member of the Shin Nippon Science Group, expanding and enhancing our contract testing items and analyses, and we can quickly respond to the procurement of various testing materials (such as animals). Non-Clinical Trial Business We accept safety and efficacy testing for pharmaceuticals, chemicals, pesticides, food, medical devices, and more. We conduct in vivo tests using small animals, rabbits, dogs, and monkeys, as well as in vitro tests using bacteria and cells, and various alternative method tests. Additionally, we specialize in the creation of SEND data required for FDA applications for new drugs, and we also undertake work related to SEND conversion and QC for data creation and conversion only. Our facility was the first in Japan to obtain full accreditation from AAALAC International (the Association for Assessment and Accreditation of Laboratory Animal Care International), and we are committed to international standards of animal welfare. We also propose tests necessary for various applications and registrations in compliance with regulations in different countries and regions.