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  4. Protein Research Reagents
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  6. Monoclonal Antibody Production Contract Service "Antibody Craftsman"

Monoclonal Antibody Production Contract Service "Antibody Craftsman"

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last updated:Sep 01, 2021

ジーンフロンティア
ジーンフロンティア
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Success-based reward! We will deliver antibodies that distinguish slight differences in 7 weeks.

Are you having trouble with the low specificity of conventional monoclonal antibodies? With "Antibody Artisan," you can produce antibodies targeting specific regions, resulting in antibodies with higher specificity. For example, we can produce antibodies such as: ■ Antibodies that identify post-translational modifications ■ Antibodies that specifically recognize homologous regions ■ Antibodies that distinguish between a few amino acid substitutions or deletions ■ Antibodies that recognize denatured proteins "Antibody Artisan" employs a unique technology (a library of 45 billion types of artificial human antibodies and phage display) that does not use animal immunization, allowing us to design antigens and select strategically. All work is done in vitro, enabling us to deliver antibodies as quickly as seven weeks after receiving the antigen. Additionally, the antibodies obtained through this service can be expressed and purified as recombinant proteins in E. coli, allowing for repeated production of additional antibodies. Antibody clones are stored for five years, and sequences are kept permanently. *For more details, please refer to the PDF materials or feel free to contact us.

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Monoclonal Antibody Production Contract Service "Antibody Craftsman"

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▼First, from Planning▼ The "Antibody Craftsman" monoclonal antibody production service begins with antibody planning as the first step when we receive inquiries about antibody production from our customers. To create antibodies suitable for the customer's intended use, we will ask about the characteristics of the antigen and the purpose of the antibody. Next, we will design the antigen according to the purpose of the antibody to be obtained, and experienced staff will propose strategic selection methods tailored to the type of antigen and the intended use of the antibody throughout the entire process. ▼Format and Reproduction of Delivered Antibodies▼ The antibodies produced will be in the form of Fab, and you can choose between monovalent or divalent options, as well as two types of tags, to be delivered in your desired format. The obtained antibodies will be purified as recombinant proteins from E. coli, allowing us to deliver them with the same quality repeatedly. Additionally, it is also easy to convert Fab into immunoglobulin isotypes such as IgA, IgE, IgG, and IgM.

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※At the shortest, 7 weeks from the receipt of the antigen.

Applications/Examples of results

Antibodies produced by "Antibody Craftsman" can be used in various applications just like antibodies produced by conventional methods. Furthermore, since they are Fab antibodies, they possess properties that can provide additional advantages in certain assay systems, such as not needing to remove the Fc region to prevent binding to receptors or to minimize the reaction of human anti-mouse antibodies (HAMA). Additionally, tag-specific detection antibodies are very useful in many applications.

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Custom Monoclonal Antibody Production Contract Service "Antibody Craftsman"

Custom Monoclonal Antibody Production Contract Service "Antibody Craftsman"

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ジーンフロンティア

ジーンフロンティア

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Gene Frontier has been expanding its business areas that contribute to the acceleration of biopharmaceuticals, including antibody drugs, and has been advancing the development of its unique technologies. Moving forward, we aim to accelerate our research and development and business development to achieve further growth on a global scale. We will continue to provide unique technologies and services for the development of innovative pharmaceuticals and diagnostic drugs, striving to be a trusted partner for our customers and contribute to 21st-century healthcare.

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