We are introducing Contipro's hyaluronic acid derivatives, such as sodium hyaluronate and hydrolyzed sodium hyaluronate, which have unique efficacy.
Contipro is a biotechnology company located in the Czech Republic. It is a global manufacturer that produces and sells various active ingredients, primarily sodium hyaluronate, in the pharmaceutical and cosmetic fields, supplying to over 60 countries for approximately 30 years. The listed products are categorized into three groups: sodium hyaluronate, natural polysaccharides, and peptides. <Sodium Hyaluronate> We offer grades with a molecular weight distribution ranging from 2.3 million Da to 10,000 Da, and we have confirmed differences in efficacy due to varying skin permeability based on molecular weight through Vivo and Vitro data. Additionally, we also have hydrolyzed sodium hyaluronate as a grade with excellent skin permeability. <Derivatives> We have confirmed through Vivo and Vitro data that sodium hyaluronate possesses not only its inherent properties of moisturizing, barrier function, anti-wrinkle, and calming effects but also efficacy in whitening, sebum secretion regulation, sebum suppression, and improvement of skin texture. *For more details, please download the PDF or feel free to contact us.
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basic information
Hyaluronic acid derivatives are available in four products. ■HyWhite: A product that incorporates linolenic acid into hyaluronic acid, maximizing the whitening effect of alpha-linolenic acid. ■HyWhite: Enhances the stability of linolenic acid through vesicles formed by itself, also improving skin permeability. ■Delcore: A product that incorporates oleic acid, forming polymer micelles of about 100 nm, which can improve the permeability of active ingredients. Additionally, it has been confirmed through Vivo data that Delcore itself has effects such as increasing sebum levels. ■Cross Linked HA: A powder-type cross-linked hyaluronic acid manufactured using a unique patented technology. It not only provides an instant effect against wrinkles but also allows for the controlled release of water-soluble substances like vitamin B3. By controlling the release, the effectiveness of water-soluble active ingredients can be maximized. ■Tenneliderm: A product chemically modified with hexanoic acid. The effectiveness, including anti-inflammatory effects, has been confirmed. *For more details, please download the PDF or feel free to contact us.
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Can be used in various formulations such as lotions, emulsions, creams, and gels. Functions as a film former. Applicable to various product concepts related to anti-aging, skin aging, fine lines, wrinkles, transparency, pigmentation, skin tone uniformity, smoothness, elasticity, and more. Delcore and Cross Linked HA can be used as permeation enhancers and sustained-release bases.
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Starting as an import trading company in 1927, we have been developing our business with many overseas suppliers and domestic customers over the years. Through our services of connecting the two together, Higuchi has become the well trusted "Japan distribution channel" for suppliers, and the "dependable vendor" who provides a stable supply of the latest high-valued overseas products to customers. Today, we conduct not only importing but also exporting businesses, trilateral trades, and overseas business investments as well. We have also expanded to local subsidiaries in the United States and China, to which we are able to effectively network overseas. Higuchi believes in the criticalness of providing a stable supply to customers, and we also place the highest priority on the coexistence with suppliers, to whom we can mutually develop together in a long-term perspective. Your support and consideration to our corporate philosophy would be much appreciated.
