Recognizing the N-linked glycan structure of the antibody Fc region! Lineup of analysis and purification columns! 【Affinity chromatography columns】
■ High-speed analysis column "TSKgel FcR-IIIA-NPR" - Capable of recognizing differences in the N-linked glycan structures of the antibody Fc region and separating antibodies with different ADCC activities. - Liganded with recombinant human Fcγ receptor IIIa, offering improved stability compared to the native type. - Allows for direct separation of antibody samples without the need for purification or pre-treatment. - Separation can be achieved in a short time (20 minutes). (Including equilibration time, measurements can be made in 30 minutes per cycle.) ■ Preparative column "TSKgel FcR-IIIA-5PW" - Demonstrates equivalent separation selectivity as it uses the same ligand as TSKgel FcR-IIIA-NPR. - Capable of loading approximately 5 mg of antibody sample. - Allows for the collection of the amount necessary for structural analysis and activity measurement in a single preparative chromatography run. *For more details, please refer to the PDF document or feel free to contact us.*
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【Specifications】 * Analytical Column ■ Product Name: TSKgel FcR-IIIA-NPR ■ Particle Size: 5μm ■ Column Size: 4.6mm I.D. × 7.5cm * Preparative Column ■ Product Name: TSKgel FcR-IIIA-5PW ■ Particle Size: 10μm ■ Column Size: 7.8mm I.D. × 7.5cm * For more details, please refer to the PDF document or feel free to contact us.
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【Main Target Substances and Uses】 ■ Antibodies ■ Fc fusion proteins ■ Screening of cell lines ■ Optimization of culture conditions ■ Management of upstream manufacturing processes ■ Product lot management *For more details, please refer to the PDF document or feel free to contact us.
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The BioScience Division is engaged in business in the "Measurement Field," which includes liquid chromatography, columns, and separation agents, and the "Diagnostics Field," which focuses on immunodiagnostics, glycohemoglobin analysis, and genetic testing. In each field, we are expanding our product lineup based on distinctive technologies and establishing sales bases not only in Japan but also overseas for global business development. Additionally, the BioScience Division consistently handles everything from the development, manufacturing, and sales of equipment and reagents to maintenance and customer support, all managed by the Tosoh Group, including its affiliated companies.