Transformation of Multiplex Assays Simplex
Simpleplex Ella is a fully automated multi-analyte immunoassay system. Although it is multi-analyte, it is not multiplexed. The reaction cells corresponding to the wells are independent (singleplex), making it an evolved ELISA with no cross-reactivity. It will be an ideal platform for biomarker measurement in clinical development or treatment of cancer immunotherapy and CAR-T cell therapy.
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basic information
**Features** - Easy operation - Factory-calibrated standard curve No calibrator measurement is required for each measurement. - Dedicated cartridges (formats for samples × analysis: 16×4, 32×4, 32×8, 72×1) Simplex assays not only demonstrate the same specificity as ELISA but also have sub-pico level detection limits, a dynamic range of 4-5 logs, and performance with single-digit CV values. - Multi-analysis with independent microchannels Multiple singleplex assays can be performed simultaneously on one sample. The sample is divided into independent microchannels for reaction, with no cross-reactivity at all. - Support for user-customized assays Custom cartridges allow users to freely choose target proteins. With dedicated digoxin cartridges for 48 samples, a dedicated custom reagent kit, and the user's unique target antibodies, users can analyze their specific target proteins using Ella.
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Applications/Examples of results
It is used not only by research institutions and pharmaceutical companies around the world but also by CRO companies. • Covance • PRA • PPD • Microcoat • SGS • Immunologix • SBH • Athersys • Frontage • Qwest • Q2 • Charles River In addition, there are application examples such as measurements of human aqueous humor at Roshe, aside from cytokine measurements in blood. Our company’s webinar site: https://www.proteinsimple.com/webinar_simple_plex.html Video title: Advances in Clinical Immunoassays: Applications in Oncology and Ophthalmology
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Company information
Protein Simple Japan Co., Ltd. is a member of a division based on Bio-Techne's protein-related products. We provide a wide range of tools, from immunoassay systems that quantify protein expression to systems that elucidate the structure and purity of protein-based pharmaceuticals. Please feel free to contact us if you have any inquiries. Contact email address: info.japan@proteinsimple.com X (formerly Twitter): https://x.com/ProteinSimpleJ