Achieving the best mixed-mode solid-phase extraction for target compounds in LC-MS/HPLC analysis through optimal selection of reversed-phase and cation exchange.
The PCX series is a polymer-based mixed-mode solid-phase extraction column that combines reversed-phase and cation exchange. By selecting the optimal option from PSCX, HPSCX, and PWCX based on the strength of reversed-phase and the differences between strong cation/weak cation exchange, you can achieve highly selective solid-phase extraction of target toxins, drugs, or their metabolites. *For more details, please download the PDF or contact us.*
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basic information
• Three types of columns support cation exchange solid-phase extraction for various target molecules. • All three types of columns utilize a mixed-mode packing material composed of cation exchange mode and reversed-phase mode. • All three types of columns use PSDVB resin as the support material. • The HPSCX column has a stronger reversed-phase mode compared to the PSCX column, making it optimal for solid-phase extraction of highly polar target molecules. • The PWCX column is used for weak cation exchange SPE. • High adsorption capacity packing material allows for extraction concentrated to 50μl using NBE type columns/plates. • The selection of a 96-well plate type automates the process with A200.
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Applications/Examples of results
• Removal of salts and fluorescent dyes from protein and peptide samples • Purification of target molecules by reverse phase or ion exchange chromatography • Purification of plasmids and DNA • Buffer exchange before sample fractionation • SPE purification of steroids, catecholamines, TDM, DoA, vitamins, etc.
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Company information
Tecan is a company that was established in Switzerland in 1980, specializing in the manufacturing and development of life science research support equipment. With the support of many customers, we were able to celebrate our 30th anniversary in Japan in 2022. Tecan Japan operates two businesses. One is the life sciences business, which delivers Tecan-branded products such as automated pipetting systems and microplate readers to end-users. The other is the partnering business, which provides components and equipment as OEM products for partner companies. Our customers span a wide range of fields, including disease research, drug discovery, biotechnology, clinical testing (such as cancer diagnosis, infectious disease diagnosis, and testing centers), scientific analysis, and robotic surgery. Our mission is to improve people's lives and health. Tecan Japan aims to contribute to global health care innovation from the life sciences industry to clinics by supporting our customers' daily activities.