An innovative solution that enables analysis at the single particle level: Nano FCM Flare & Auto20 now available.
Innovative solution for analysis at the single particle level ★NanoFCM Flare★ Measurement of biological particles from 40nm For the production and evaluation of EVs, viruses, nucleic acid drugs, etc. ★NanoFCM Auto20★ High-throughput model equipped with auto-sampling and cleaning functions ■Capable of fluorescent detection of single molecules, phenotypes are quantified from marker intensity ■High-resolution size distribution comparable to TEM ■Measures the number concentration of all particles and fluorescently labeled particles ■Quantifies particle populations with up to two fluorescent labels
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■ "Simultaneous discrimination of 'particle size' and 'type' is possible! By equipping the side-scattered light detector with an SPCM (Single Photon Counting Module), high sensitivity is achieved. In addition to measuring particles, it can distinguish between biological and non-biological entities. Through fluorescence measurement, phenotyping (determining phenotype) of labeled biological particles (such as EVs), proteins, nucleic acids, lipids, etc., can be evaluated at the single-molecule level."
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Phenotyping analysis of extracellular vesicles (EVs) on a single particle basis ■Quantification of EV abundance NanoFCM has fluorescence sensitivity that can detect at the single molecule level. It is possible to measure both endogenous fluorescence and fluorescent labeling for each EV particle, allowing for the differentiation between fluorescent and non-fluorescent EV populations. Proteins, nucleic acids, and lipids can also be evaluated at the single particle level, measuring the relative amount of their presence based on fluorescence signal intensity, enabling phenotyping at the single EV particle level. ■Evaluation of miRNA levels within EVs EVs contain RNA, DNA, proteins, lipids, and metabolites both internally and on their surface, and are likened to vesicle cargo. This EV cargo is transferred to recipient cells, resulting in multifaceted responses. The function of these EVs can be assessed by measuring their composition or evaluating their functionality.
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Our researcher customers are dedicated to their research day and night to "change the world" and "create the future." The products we handle reach the hands of researchers, contributing to the advancement of science and technology in Japan. Our company plays a role in creating such an exciting future and has been supporting researchers in the niche fields of environment, materials, and biotechnology as a top partner for 50 years since our establishment.