[Workshop Announcement] "New Technologies for EV, LNP, and Gene Introduction 2025: A Workshop to See, Touch, and Listen"

An innovative solution that enables analysis at the single particle level: Nano FCM Flare & Auto20 now available.

Innovative solution for analysis at the single particle level ★NanoFCM Flare★ 　Measurement of biological particles from 40nm 　For the production and evaluation of EVs, viruses, nucleic acid drugs, etc. ★NanoFCM Auto20★ High-throughput model equipped with auto-sampling and cleaning functions ■Capable of fluorescent detection of single molecules, phenotypes are quantified from marker intensity ■High-resolution size distribution comparable to TEM ■Measures the number concentration of all particles and fluorescently labeled particles ■Quantifies particle populations with up to two fluorescent labels

• Other physicochemical equipment
• Particle Counter
• Analytical Equipment and Devices

Easy, quick, and convenient: Interference light microscopy observation (ILM) nanoparticle measurement.

■One Drop & One Click Easy and Fast Measurement One drop (5μL), accurately quantifying nanoparticles in as little as 40 seconds ■Interferometric Light Microscopy Observation of Nanoparticle Measurement (ILM: Interferometric Light Microscopy) ■Measurement of unlabelled and unpurified samples ■High-precision measurement of particle size and concentration even for polydisperse samples

• Other physicochemical equipment
• Particle Counter
• Analytical Equipment and Devices

Exoid (TRPS) enables accurate and reliable zeta potential measurements compared to other methods.

Exoid (TRPS) enables accurate and reliable zeta potential measurements compared to other methods. 【Features】 ■ Simultaneous measurement of zeta potential and particle size for each particle ■ Unbiased results obtained through true zeta potential distribution ■ Measurement of charge at physiological strength in buffer ■ Measurement principle is the electrical resistance nanopulse method (TRPS) ■ Measurement of changes in surface charge *For more details, please refer to the materials or feel free to contact us.

• Other measurement, recording and measuring instruments

Extract high-purity extracellular vesicle extracts! Automatic recovery devices for extraction and cleaning are also available!

The "qEV Series" is an exosome extraction kit that can extract highly pure extracellular vesicle extracts. The "qEV Extracellular Vesicle Extraction Kit" has obtained the international standard for quality management of medical devices, ISO 13485. It allows for the separation and purification of exosomes and extracellular vesicles in just 15 minutes. The "AFC qEV Column Automatic Recovery Device" automates the process from extraction to cleaning, making the extraction of EVs much easier. 【Features】 ■ Kits can be selected based on research purposes and sample volume. ■ High-efficiency and high-precision analysis can be achieved when used with qNano. ■ Separation can be performed while maintaining the biological and morphological characteristics of EVs. ■ Improved sensitivity and accuracy for analysis and measurement. ■ Obtained the international standard for quality management of medical devices, ISO 13485. *For more details, please refer to the PDF materials or feel free to contact us.

• Separation device
• Other physicochemical equipment
• Analytical Equipment and Devices

Extraction to cleaning, making the work easier automatically!

The "AFC" is an automatic recovery device for qEV columns that simplifies the extraction process of extracellular vesicles (EVs) from extraction to cleaning. By automatically recovering fractions based on weight detection, it minimizes variability due to manual work, achieving greater reproducibility than ever before. Additionally, it features an RFID tag (an IC tag that can store information) to manage manufacturing and QA data, usage counts, and cleaning cycles. When used in conjunction with the qEV series "Extracellular Vesicle Extraction Kit" and the nanoparticle multi-analyzer "Exoid," it enables high recovery of extracellular vesicle extraction. 【Features】 ■ Fully automated extraction to cleaning, making EV extraction work easier ■ Automatic recovery of fractions based on weight detection, minimizing variability due to manual work ■ Achieves greater reproducibility than ever before * Please use qEV and AFC for basic research purposes only. They cannot be used for clinical or medical procedures. * For more details, please refer to the PDF materials or feel free to contact us.

• Separation device
• Other physicochemical equipment
• Analytical Equipment and Devices

Improvement of each step in the extracellular vesicle (EV) research workflow.

In EV research, accurate and efficient separation from biological samples is essential. Characterization and quantification of EVs are performed to confirm purity and consistency. Subsequently, biological activity is assessed through functional assays, and the potential for therapy is explored. Innovative products play a crucial role in this complex process.

• Staining Reagents

Fluorescent staining of lipid bilayers without false positives

Cutting-edge visualization using fluorescent staining The characteristics of Acoerela dye are its high quantum yield (>25%) and specificity. A significant increase in fluorescence intensity is observed only when the fluorescent dye binds to the target, during which the hydrophobicity of the environment surrounding the dye changes. The substantial difference in emission profiles between bound and unbound dyes underlies the "light-on" mechanism.

• Staining Reagents

Cell-friendly gene introduction: Next-generation transfection platform

Using the latest photoporation technology, a wide variety of cells, including iPS cells and CAR-T cells, can be introduced with various substances such as nucleic acids, proteins, and CRISPR/Cas9 RNPs. This method provides minimal damage during introduction, high survival rates, and achieves efficient transfection with high throughput. Photoporation is a gentle method for delivering payloads to cells based on the interaction between pulsed laser light and photothermal nanosenstizers. When laser light is applied to unique nanosenstizers adjacent to the cells, temporary pores are formed in the cell membrane through localized plasmonic reactions, allowing external payloads to enter the cytoplasm with minimal impact on cell survival and function. This technology serves as a next-generation transfection platform that efficiently, flexibly, and safely delivers various payloads to a wide range of cells, including primary cells, where transfection is challenging.

• Genetic Analysis Software

We would like to extend our heartfelt congratulations on the continued prosperity of your esteemed company. Our company will be exhibiting at the following trade show, where we will introduce a number of products, including our new product, the Pillow Packaging Full Air Tightness Inspection Machine MSQ-2003. We sincerely apologize for the inconvenience during your busy schedule, but we would like to invite you to visit us at this opportunity. 【 Exhibition Name 】 JAPAN PACK 2025 Japan Packaging Industry Exhibition https://www.japanpack.jp/ 【 Dates 】 October 7 (Tuesday) to October 10 (Friday), 2025 *4 days 10:00 AM to 5:00 PM 【 Venue / Booth Number 】 Tokyo Big Sight / East Hall 8, Booth 8-505

Our company will be exhibiting at the "14th Fukushima Renewable Energy Industry Fair (REIF Fukushima 2025)" held at Big Palette Fukushima from Thursday, October 16, 2025, to Friday, October 17, 2025. Focusing on energy visualization solutions that can be started "immediately," we will introduce power monitoring solutions for each equipment and load through examples of the overall system configuration. 【Main Exhibited Products】 - Gateway BOX We will showcase the "Gateway BOX," a product that packages the necessary equipment for easy adoption of the visualization system. - PAL-Plus type E2 (Scheduled for release soon) We will introduce a "smart" clamp CT that can easily measure power for three-phase three-wire and single-phase three-wire systems (scheduled for release soon). - CEW-M4 / PAL-Plus As a monitoring system that can display power consumption and remaining power capacity, we will present the manager software "CEW-M4," which supports up to 20,000 points, and the Modbus-compatible AC current sensor "PAL-Plus." We sincerely look forward to your visit.

Toyo Machinery Co., Ltd. will be exhibiting at the high-performance film exhibition held at Makuhari Messe. The High-Performance Film Exhibition - FILMTECH JAPAN - is a specialized exhibition where molding processing technologies, materials, and functional films themselves are showcased all in one place. Experts from various fields, including the technology departments of film manufacturers, electronics, automotive, batteries, construction and building materials, and food and beverages, will attend in search of functional films. At Toyo Machinery, we will display actual machines for waviness correction and wrinkle removal while running film, allowing you to see their effects and functions. We will also introduce the quality management system (weight, thickness, moisture, etc.) from the German company Marlo. ↓↓↓Toyo Machinery's exhibitor information↓↓↓ https://www.material-expo.jp/tokyo/ja-jp/search/2025/directory/details.org-a11cd7f5-2a7b-4ea7-85ce-cde885acd2dd.html#/ *If you wish to attend, you can pre-register via the "Details & Application" link below. We sincerely look forward to your visit.

We will be exhibiting at the Okayama Technology Exhibition (OTEX) 2025, which will be held at Convex Okayama from November 12 (Wednesday) to November 13 (Thursday), 2025. We will showcase our eco-board pallets (paper pallets) as well as comprehensive packaging solutions suitable for one-way shipments such as exports. Our products will assist in addressing challenges related to environmental considerations in the context of the SDGs and the promotion of white logistics. ■ Our booth: 46 (Company products) We sincerely look forward to your visit, and we hope you can come together.

We will be exhibiting at the Okayama Technology Exhibition (OTEX) 2025 Online Exhibition, which will be held online from October 31, 2025, to December 19, 2025. It will be previewed prior to the physical exhibition, so please take a look. If you are interested, we will also have the actual products on display at the physical exhibition. We will showcase a range of packaging solutions suitable for one-way shipments, including our eco-board pallets (paper pallets). Please consider how our pallets can help solve logistics issues and contribute to environmental initiatives related to the SDGs.