[Workshop Announcement] "New Technologies for EV, LNP, and Gene Introduction 2025: A Workshop to See, Touch, and Listen"

An innovative solution that enables analysis at the single particle level: Nano FCM Flare & Auto20 now available.

Innovative solution for analysis at the single particle level ★NanoFCM Flare★ 　Measurement of biological particles from 40nm 　For the production and evaluation of EVs, viruses, nucleic acid drugs, etc. ★NanoFCM Auto20★ High-throughput model equipped with auto-sampling and cleaning functions ■Capable of fluorescent detection of single molecules, phenotypes are quantified from marker intensity ■High-resolution size distribution comparable to TEM ■Measures the number concentration of all particles and fluorescently labeled particles ■Quantifies particle populations with up to two fluorescent labels

• Other physicochemical equipment
• Particle Counter
• Analytical Equipment and Devices

Exoid (TRPS) enables accurate and reliable zeta potential measurements compared to other methods.

Exoid (TRPS) enables accurate and reliable zeta potential measurements compared to other methods. 【Features】 ■ Simultaneous measurement of zeta potential and particle size for each particle ■ Unbiased results obtained through true zeta potential distribution ■ Measurement of charge at physiological strength in buffer ■ Measurement principle is the electrical resistance nanopulse method (TRPS) ■ Measurement of changes in surface charge *For more details, please refer to the materials or feel free to contact us.

• Other measurement, recording and measuring instruments

Extract high-purity extracellular vesicle extracts! Automatic recovery devices for extraction and cleaning are also available!

The "qEV Series" is an exosome extraction kit that can extract highly pure extracellular vesicle extracts. The "qEV Extracellular Vesicle Extraction Kit" has obtained the international standard for quality management of medical devices, ISO 13485. It allows for the separation and purification of exosomes and extracellular vesicles in just 15 minutes. The "AFC qEV Column Automatic Recovery Device" automates the process from extraction to cleaning, making the extraction of EVs much easier. 【Features】 ■ Kits can be selected based on research purposes and sample volume. ■ High-efficiency and high-precision analysis can be achieved when used with qNano. ■ Separation can be performed while maintaining the biological and morphological characteristics of EVs. ■ Improved sensitivity and accuracy for analysis and measurement. ■ Obtained the international standard for quality management of medical devices, ISO 13485. *For more details, please refer to the PDF materials or feel free to contact us.

• Separation device
• Other physicochemical equipment
• Analytical Equipment and Devices

Extraction to cleaning, making the work easier automatically!

The "AFC" is an automatic recovery device for qEV columns that simplifies the extraction process of extracellular vesicles (EVs) from extraction to cleaning. By automatically recovering fractions based on weight detection, it minimizes variability due to manual work, achieving greater reproducibility than ever before. Additionally, it features an RFID tag (an IC tag that can store information) to manage manufacturing and QA data, usage counts, and cleaning cycles. When used in conjunction with the qEV series "Extracellular Vesicle Extraction Kit" and the nanoparticle multi-analyzer "Exoid," it enables high recovery of extracellular vesicle extraction. 【Features】 ■ Fully automated extraction to cleaning, making EV extraction work easier ■ Automatic recovery of fractions based on weight detection, minimizing variability due to manual work ■ Achieves greater reproducibility than ever before * Please use qEV and AFC for basic research purposes only. They cannot be used for clinical or medical procedures. * For more details, please refer to the PDF materials or feel free to contact us.

• Separation device
• Other physicochemical equipment
• Analytical Equipment and Devices

Improvement of each step in the extracellular vesicle (EV) research workflow.

In EV research, accurate and efficient separation from biological samples is essential. Characterization and quantification of EVs are performed to confirm purity and consistency. Subsequently, biological activity is assessed through functional assays, and the potential for therapy is explored. Innovative products play a crucial role in this complex process.

• Staining Reagents

Fluorescent staining of lipid bilayers without false positives

Cutting-edge visualization using fluorescent staining The characteristics of Acoerela dye are its high quantum yield (>25%) and specificity. A significant increase in fluorescence intensity is observed only when the fluorescent dye binds to the target, during which the hydrophobicity of the environment surrounding the dye changes. The substantial difference in emission profiles between bound and unbound dyes underlies the "light-on" mechanism.

• Staining Reagents

Cell-friendly gene introduction: Next-generation transfection platform

Using the latest photoporation technology, a wide variety of cells, including iPS cells and CAR-T cells, can be introduced with various substances such as nucleic acids, proteins, and CRISPR/Cas9 RNPs. This method provides minimal damage during introduction, high survival rates, and achieves efficient transfection with high throughput. Photoporation is a gentle method for delivering payloads to cells based on the interaction between pulsed laser light and photothermal nanosenstizers. When laser light is applied to unique nanosenstizers adjacent to the cells, temporary pores are formed in the cell membrane through localized plasmonic reactions, allowing external payloads to enter the cytoplasm with minimal impact on cell survival and function. This technology serves as a next-generation transfection platform that efficiently, flexibly, and safely delivers various payloads to a wide range of cells, including primary cells, where transfection is challenging.

• Genetic Analysis Software

We will be exhibiting at the "P-MEC Japan 2025 Pharmaceutical Ingredients and Equipment Exhibition" held at Tokyo Big Sight. During the event, we will showcase various products. We invite all relevant parties to come and visit us. 【Suppliers】 ・LAUDA

In conversations with engineers in the manufacturing industry, I have increasingly received the following inquiries: - Confusion in interpreting experimental results - Taking time to organize hypotheses regarding the causes of troubles - Uncertainty about how to evaluate the impact of changes in raw materials or processes - Anxiety about the judgment of results from external testing organizations Considering the themes being discussed internally, I thought, "Could there be an opportunity to provide support as a third-party engineer for brainstorming?" Therefore, we have decided to establish a trial "Technical Consultation Opportunity." 【Overview of Technical Consultation】 - Target: Engineers and research and development personnel in the manufacturing industry, etc. - Content: Organizing experimental plans, interpreting results, organizing trouble hypotheses, etc. - Format: Online (approximately 60 minutes) - Cost: Free for the first consultation - Recruitment: Limited to 5 companies *Please note that we will take sufficient care to respect the confidentiality of each company's information and will not disclose anything externally. We hope you can consult with us with confidence. This will be more of a space for open exchange of opinions between researchers and engineers rather than a sales proposal. If you have any themes you are currently considering, please feel free to reach out. If you are interested, please contact us with "Request for Technical Consultation," and we will provide you with further details.

Thank you very much for visiting our booth this time. Thanks to you, we had the opportunity to introduce our products and technologies to many customers, making it a very meaningful time. If you have any questions regarding the exhibition content or if you would like to discuss specific considerations or estimates, please feel free to contact us. We will be happy to provide proposals tailored to your needs.

[Lecture Topics] 1. About AI Robotics Tomoya Yokoyama, Section Chief, Robot Policy Office, Industrial Machinery Division, Ministry of Economy, Trade and Industry *The content of the lecture may change. 2. Development of Remote-Controlled Robots Aiming for a Realistic Operating Experience ~Visual and auditory transmission through ultra-low latency, high presence, and high immersion~ Hiroshi Inagaki, Senior Manager, Collaborative Robotics Group, R-Frontier Department, Future Creation Center, Toyota Motor Corporation 3. The Impact of Japanese-Made Humanoids Yasuke Ono, President, Donut Robotics Inc.

[Speaker] Inclusive Design Designer Yoko Nakao [Key Lecture Content] Products are not selling, differentiation is difficult, and regulations are changing. As product development and facility management reach a significant turning point, inclusive design, which involves engaging people who have previously been excluded from the development process to collaboratively think of solutions, is gaining attention as a method for creating new value. Additionally, practicing inclusive design is expected to enhance not only customer engagement but also employee engagement. In this seminar, based on 20 years of experience leading universal design and inclusive design with diverse characteristics both inside and outside a comprehensive electronics manufacturer, I will specifically explain how to practice inclusive design to create new value. [Lecture Items] 1. Inclusive Design as a New Growth Engine 2. Increasing the Resolution of Diversity 3. Inclusive Design Process 4. Side Effects - Ripple Effects on Talent Development and Recruitment 5. Conclusion 6. Q&A / Business Card Exchange