[Workshop Announcement] "New Technologies for EV, LNP, and Gene Introduction 2025: A Workshop to See, Touch, and Listen"

An innovative solution that enables analysis at the single particle level: Nano FCM Flare & Auto20 now available.

Innovative solution for analysis at the single particle level ★NanoFCM Flare★ 　Measurement of biological particles from 40nm 　For the production and evaluation of EVs, viruses, nucleic acid drugs, etc. ★NanoFCM Auto20★ High-throughput model equipped with auto-sampling and cleaning functions ■Capable of fluorescent detection of single molecules, phenotypes are quantified from marker intensity ■High-resolution size distribution comparable to TEM ■Measures the number concentration of all particles and fluorescently labeled particles ■Quantifies particle populations with up to two fluorescent labels

• Other physicochemical equipment
• Particle Counter
• Analytical Equipment and Devices

Exoid (TRPS) enables accurate and reliable zeta potential measurements compared to other methods.

Exoid (TRPS) enables accurate and reliable zeta potential measurements compared to other methods. 【Features】 ■ Simultaneous measurement of zeta potential and particle size for each particle ■ Unbiased results obtained through true zeta potential distribution ■ Measurement of charge at physiological strength in buffer ■ Measurement principle is the electrical resistance nanopulse method (TRPS) ■ Measurement of changes in surface charge *For more details, please refer to the materials or feel free to contact us.

• Other measurement, recording and measuring instruments

Extract high-purity extracellular vesicle extracts! Automatic recovery devices for extraction and cleaning are also available!

The "qEV Series" is an exosome extraction kit that can extract highly pure extracellular vesicle extracts. The "qEV Extracellular Vesicle Extraction Kit" has obtained the international standard for quality management of medical devices, ISO 13485. It allows for the separation and purification of exosomes and extracellular vesicles in just 15 minutes. The "AFC qEV Column Automatic Recovery Device" automates the process from extraction to cleaning, making the extraction of EVs much easier. 【Features】 ■ Kits can be selected based on research purposes and sample volume. ■ High-efficiency and high-precision analysis can be achieved when used with qNano. ■ Separation can be performed while maintaining the biological and morphological characteristics of EVs. ■ Improved sensitivity and accuracy for analysis and measurement. ■ Obtained the international standard for quality management of medical devices, ISO 13485. *For more details, please refer to the PDF materials or feel free to contact us.

• Separation device
• Other physicochemical equipment
• Analytical Equipment and Devices

Extraction to cleaning, making the work easier automatically!

The "AFC" is an automatic recovery device for qEV columns that simplifies the extraction process of extracellular vesicles (EVs) from extraction to cleaning. By automatically recovering fractions based on weight detection, it minimizes variability due to manual work, achieving greater reproducibility than ever before. Additionally, it features an RFID tag (an IC tag that can store information) to manage manufacturing and QA data, usage counts, and cleaning cycles. When used in conjunction with the qEV series "Extracellular Vesicle Extraction Kit" and the nanoparticle multi-analyzer "Exoid," it enables high recovery of extracellular vesicle extraction. 【Features】 ■ Fully automated extraction to cleaning, making EV extraction work easier ■ Automatic recovery of fractions based on weight detection, minimizing variability due to manual work ■ Achieves greater reproducibility than ever before * Please use qEV and AFC for basic research purposes only. They cannot be used for clinical or medical procedures. * For more details, please refer to the PDF materials or feel free to contact us.

• Separation device
• Other physicochemical equipment
• Analytical Equipment and Devices

Improvement of each step in the extracellular vesicle (EV) research workflow.

In EV research, accurate and efficient separation from biological samples is essential. Characterization and quantification of EVs are performed to confirm purity and consistency. Subsequently, biological activity is assessed through functional assays, and the potential for therapy is explored. Innovative products play a crucial role in this complex process.

• Staining Reagents

Fluorescent staining of lipid bilayers without false positives

Cutting-edge visualization using fluorescent staining The characteristics of Acoerela dye are its high quantum yield (>25%) and specificity. A significant increase in fluorescence intensity is observed only when the fluorescent dye binds to the target, during which the hydrophobicity of the environment surrounding the dye changes. The substantial difference in emission profiles between bound and unbound dyes underlies the "light-on" mechanism.

• Staining Reagents

Cell-friendly gene introduction: Next-generation transfection platform

Using the latest photoporation technology, a wide variety of cells, including iPS cells and CAR-T cells, can be introduced with various substances such as nucleic acids, proteins, and CRISPR/Cas9 RNPs. This method provides minimal damage during introduction, high survival rates, and achieves efficient transfection with high throughput. Photoporation is a gentle method for delivering payloads to cells based on the interaction between pulsed laser light and photothermal nanosenstizers. When laser light is applied to unique nanosenstizers adjacent to the cells, temporary pores are formed in the cell membrane through localized plasmonic reactions, allowing external payloads to enter the cytoplasm with minimal impact on cell survival and function. This technology serves as a next-generation transfection platform that efficiently, flexibly, and safely delivers various payloads to a wide range of cells, including primary cells, where transfection is challenging.

• Genetic Analysis Software

We want to improve our operations with AI, but what exactly can we do... For those who want to actually try out and compare services, we have an announcement. The electronic contract and document management service paperlogic will be exhibiting at the 'Business Innovation Fair 2025 Autumn in Makuhari' hosted by Otsuka Shokai on November 13th (Thursday) and 14th (Friday) at the Hotel Green Tower Makuhari. Seminars on business improvement and AI utilization will also be held, so if you are nearby, please come and visit us. ● We will also be conducting product demonstrations of paperlogic at the venue. The biggest feature of paperlogic is that it is easy to use and simple, yet it complies with all document management regulations, including the Electronic Bookkeeping Act. We invite you to experience this simplicity firsthand.

What should we start with for the digital transformation (DX) in the quality assurance department? ■ Transitioning from manual input to automatic input for inspection sheet creation! ■ Connecting measurement result input tasks to digital calipers for automatic judgment! We propose to not only maximize the use of CAD drawings to streamline inspection operations but also to initiate the digital transformation starting from inspection tasks.

The electric actuator manufacturer LINAK will be exhibiting for the first time at the "International Robot Exhibition (iREX 2025)" held at Tokyo Big Sight. This exhibition is highly regarded both domestically and internationally as "one of the largest robot specialized exhibitions in the world." At the venue, we plan to showcase our lifting column "LC3 IC Elevate," which is suitable for lifting applications with collaborative robots, as well as electric cylinder solutions for AGV/AMR. We will propose sustainable and flexible automation solutions. Please be sure to visit our booth.

Fuji Chemical Co., Ltd. will be exhibiting at the "39th Hokkaido Business EXPO" held at Access Sapporo. This exhibition is one of the largest business events in Hokkaido. We plan to showcase GRP pipes for wastewater, pipes for hot springs, and pipes for plants. We sincerely look forward to your visit.

Fujikako Co., Ltd. will be exhibiting at the "17th International Food Trade Fair Food Messe in Niigata 2025," held at the Toki Messe Niigata Convention Center. This exhibition is an "International Comprehensive Food Trade Fair" that creates new value from tradition to advanced trends, bringing together participants from across the country to Niigata and from Niigata to the nation. We plan to showcase our Fuji GRP pipes for wastewater. We sincerely look forward to your visit.