『ciKIC IEC Maturation Medium』

A culture medium that enables the maturation of human iPS cell-derived intestinal epithelial cells, allowing the creation of a human intestinal epithelial model similar to the in vivo small intestine.

The "ciKIC IEC Maturation Medium" is a culture medium that allows for the maturation of intestinal epithelial cells derived from human iPS cells, enabling the creation of a human intestinal epithelial model. In oral drug pharmacokinetic testing, the Caco-2 cells derived from human colon cancer have traditionally been used as a model for gastrointestinal absorption and metabolism tests; however, there has been a challenge in adequately replicating the functions of the living small intestine. This product allows for the maturation of intestinal epithelial cells derived from human iPS cells, making it possible to create a human intestinal epithelial model that is similar to the living small intestine. 【Features】 ■ Capable of producing high-performance human intestinal epithelial models ■ Wide range of applications *For more details, please refer to the PDF materials or feel free to contact us. 【Keywords】 Drug discovery support, non-clinical trials, pharmacokinetics, gastrointestinal absorption tests, Caco-2, iPS-small intestine model, drug metabolism enzymes, transporters, barrier function, drug-drug interactions, functional foods, health foods, nutrient absorption, intestinal immunity, gut microbiota.

Culture mediumOther research reagentsHuman cells