We would like to introduce an invention that can suppress the aggregation of tau proteins.
Various therapeutic agents have been developed for neurodegenerative diseases up to now, but all of those actually used in treatment are symptomatic therapies, and no successful development of curative drugs has been achieved. The purpose of this invention is to provide a agent that suppresses the aggregation of tau protein, which is a cause of Alzheimer's disease and frontotemporal dementia. By suppressing the aggregation of tau protein, it becomes possible to prevent or treat neurodegenerative diseases caused by the aggregation of tau protein. [Research Overview] - Creation of a tau protein aggregation suppressor with phorbol esters as the active ingredient - It is preferable that the phorbol ester is phorbol 12-myristate 13-acetate - Capable of suppressing the aggregation of tau protein - Capable of preventing or treating neurodegenerative diseases *For more details, please refer to the PDF document or feel free to contact us.
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For more details, please refer to the PDF document or feel free to contact us.
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[Purpose] ■ Treatment or prevention of neurodegenerative diseases such as Alzheimer's disease and frontotemporal dementia.
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Yamaguchi TLO Co., Ltd. is a TLO approved by the Ministry of Education, Culture, Sports, Science and Technology and the Ministry of Economy, Trade and Industry based on the Act on the Promotion of Technology Transfer from Universities, established in November 1999 with investments from 50 faculty members of Yamaguchi University (capital of 4 million yen) before incorporation. It is a liaison-type technology transfer organization that bridges people. We return the research results from the university to society in the form of technology transfer and other means. Additionally, we are actively recruiting member companies to prioritize the disclosure of invention information and contribute to the development of the local economy through these efforts.