[Case Study] Workflow for Non-Target Analysis Using GC-MS
Introducing a case study of non-target analysis combining GC-MS and deconvolution software.
In recent years, the demand for non-target analysis has been increasing in many fields, such as odor analysis and impurity analysis, using GC-MS. This involves conducting comprehensive measurements without specifying the measurement targets through full scan MS and extracting valuable information from the vast spectral data obtained. Since the full scan MS data obtained from GC-MS can contain information on hundreds to thousands of compounds, efficiently identifying valuable information from this data is a very important challenge. Additionally, it is crucial to select the optimal pretreatment device considering high extraction capability, broad coverage, and the form and properties of the sample, in order to comprehensively extract samples without loss and introduce them into GC-MS. This application note presents a case study of non-target analysis that combines a system connecting a pretreatment device to a Thermo Scientific GC-MS instrument with AnalyzerPro, a deconvolution software from SpectralWorks.
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Thermo Fisher Scientific K.K., the Japanese subsidiary of Thermo Fisher Scientific Incorporated, is a sales company for comprehensive system analysis instruments, bio-related equipment, and research reagents. In Japan, it has bases in Yokohama, Tokyo, Osaka, Fukuoka, and Nagoya, handling various analytical instruments including mass spectrometers, various bio-related equipment, measuring instruments, medical devices, lab software, and research reagents.