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  6. 384ch Auto Patch Clamp SyncroPatch 384

384ch Auto Patch Clamp SyncroPatch 384

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SyncroPatch 384

last updated:Apr 30, 2025

ナニオンテクノロジーズジャパン 東京ラボ(東京大学内)
ナニオンテクノロジーズジャパン 東京ラボ(東京大学内)
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An automated patch clamp system capable of meeting all needs, from small-scale screening projects to high-throughput screening.

Designed to seamlessly integrate fully automated compound screening into the drug discovery process, it provides the best performance in high-throughput screening of ion channels in drug discovery, pharmacology, safety, pharmaceutical research and development, and exploratory screening departments. Additionally, by using the 32-well mode, it can be optimized for small-scale compound screening and projects. ■ Simultaneous measurement of 384 cells ■ 20,000 data points per day ■ High giga-seal success rate ■ Supports a variety of ion channel targets and enables rapid assay system development ■ Measurement of action potentials using current clamp is also possible ■ Extracellular/intracellular perfusion is possible ■ High-speed external solution exchange (up to 110 µl/s) is possible ■ Measurement section and 12 decks can be individually temperature controlled (temperature range: 10–37°C) ■ Compound plate preparation on the deck is possible ■ Single & multi-well chips available (in-house manufactured) ■ Borosilicate glass chips reduce compound adsorption ■ Approximately 8 hours of unmanned operation is possible ■ Comes with powerful analysis software ■ Validated system for CiPA

    Other physicochemical equipmentAnalytical EquipmentPatch clamp system
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384ch Auto Patch Clamp SyncroPatch 384

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basic information

The SyncroPatch 384 is a groundbreaking automated patch clamp system that integrates a patch clamp module with the state-of-the-art automated pipetting system Biomek i5. It enables simultaneous measurement of 384 cells, achieving a throughput of 20,000 data points per day. Its user-friendliness and open design support complete automation and integration into high-throughput screening (HTS). By utilizing the 32-well mode, it can cater to various throughput needs, not only for high-throughput screening but also for small-scale screening projects and academic research, maximizing the cost benefits of the NPC-384 chip. Users can select the number of wells required for experiments in units of 32 and use the remaining wells over several days. Additionally, by fully automating the program, experiments lasting about 8 hours can be conducted unattended. With its exceptional data quality and flexibility, the SyncroPatch 384 is adopted by global pharmaceutical companies, CROs, and academic institutions.

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Applications/Examples of results

We have numerous delivery achievements in the drug discovery, pharmacology, safety, pharmaceutical research and development, and exploratory screening departments of pharmaceutical companies, as well as with CROs, both domestically and internationally. *For more details, please refer to the PDF document or feel free to contact us. For inquiries regarding products, requests for demos, catalog requests, or any other inquiries, please feel free to contact us directly. Mail: info@nanion.jp

catalog(11)

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Comprehensive Catalog: Electrophysiology Experimental Equipment Catalog vol. 6

Comprehensive Catalog: Electrophysiology Experimental Equipment Catalog vol. 6

CATALOG
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384ch Auto Patch Clamp System SyncroPatch 384

384ch Auto Patch Clamp System SyncroPatch 384

PRODUCT
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【Cell and Ion Channel Measurement Example】 Auto Patch Clamp System

【Cell and Ion Channel Measurement Example】 Auto Patch Clamp System

TECHNICAL
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[Measurement Example] Nav1.5 | SyncroPatch 384i

[Measurement Example] Nav1.5 | SyncroPatch 384i

TECHNICAL
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[Measurement Example] TRP Channels | SyncroPatch 384

[Measurement Example] TRP Channels | SyncroPatch 384

TECHNICAL
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[Measurement Example] DRG Neurons | SyncroPatch 384

[Measurement Example] DRG Neurons | SyncroPatch 384

TECHNICAL
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[Measurement Example] TMEM175 | SyncroPatch 384

[Measurement Example] TMEM175 | SyncroPatch 384

TECHNICAL
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[Measurement Example] ASIC3 | SyncroPatch 384PE

[Measurement Example] ASIC3 | SyncroPatch 384PE

TECHNICAL
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[Measurement Example] HCN2 | SyncroPatch 384i

[Measurement Example] HCN2 | SyncroPatch 384i

TECHNICAL
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[Measurement Example] P2X3 and P2X2/3 Receptors | SyncroPatch 384

[Measurement Example] P2X3 and P2X2/3 Receptors | SyncroPatch 384

TECHNICAL
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Differences between Auto and Manual Patch Clamp

Differences between Auto and Manual Patch Clamp

TECHNICAL
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News about this product(16)

[Workshop Announcement] Electrophysiology Experiment Workshop 2025

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You can experience actual measurements and demonstrations using our various products. For more details about the products, please refer to the related products below. *Capacity: Approximately 10 to 20 people *Due to limited lab space, depending on the number of participants, there may be a possibility of dividing into two sessions, morning and afternoon. *Participants who register for the workshop will be contacted again once the details are finalized.

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[Seminar Announcement] Membrane Physiology Symposium Japan 2025

  • Seminar・Event

We are pleased to announce that Nanion Technologies Japan Co., Ltd. will co-host the Membrane Physiology Symposium Japan 2025 in collaboration with Professor Hideaki Kato's laboratory at the University of Tokyo's Advanced Research Center. Following the symposium, we will also hold a modest networking event, and we warmly invite you to participate. For details on the program and other information, please refer to the related PDF documents. Speakers (in alphabetical order): - Dr. Kenji Akiyoshi | Keio University, Faculty of Pharmacy - Dr. Shuutarou Katsurabayashi | Fukuoka University, Faculty of Pharmacy - Dr. Hideaki Kato | University of Tokyo, Advanced Research Center - Dr. Tomoya Kubota | Osaka University Graduate School of Medicine - Dr. Shin Hamamoto | University of Tokyo Graduate School of Agricultural and Life Sciences - Dr. Yuichiro Miyaoka | Tokyo Metropolitan Institute of Medical Science - Dr. Chai-Ann Ng | Victor Chang Cardiac Research Institute - Dr. Alexandre Santinho | Oria Bioscience - Dr. Will Seibertz | Nanion Technologies GmbH - Dr. Martin Ziller | Nanion Technologies GmbH

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[Seminar Announcement] Ion Channel Forum 2023

  • Seminar・Event

We are pleased to announce that Nanion Technologies Japan Co., Ltd. will be hosting the Ion Channel Forum 2023 in person for the first time in four years, in collaboration with Tokyo Women's Medical University. Following the forum, we will hold a modest networking event at a hotel in Tokyo. Additionally, we plan to conduct a workshop on electrophysiology using our various products the following day. Scheduled speakers (in alphabetical order): Dr. Tadashi Kimura | Veneno Technologies Co., Ltd. Dr. Takaaki Sogabe | Center for Life Creation Research, Temperature Biology Research Group Dr. Kiyoshi Takasago, Dr. Hatsue Furukawa | Axcelead Drug Discovery Partners, Inc. Dr. Takuma Takada | Advanced Research Institute for Medical Science, Tokyo Women's Medical University Dr. Hiroyuki Takeda | ProteoScience Center, Ehime University, Department of Proteo-Drug Discovery Science Dr. Tomoya Tsukazaki | Nara Institute of Science and Technology, Graduate School of Advanced Science and Technology, Bioscience Area, Structural Life Science Dr. Masafumi Doi | Daiichi Sankyo RD Novare Co., Ltd., Biological Evaluation Research Department, Discovery ADMET Group

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Announcement of Catalog Publication: Electrophysiology Experimental Equipment Catalog vol. 6

  • Catalog news

We are pleased to announce the publication of the Electrophysiology Experimental Equipment Catalog vol. 6. 【Featured Products in the Catalog】 ■ Auto Patch Clamp System Ideal for evaluating the effects of compounds on ion channels and for functional and structural analysis of ion channels. From a compact system that allows you to check data immediately at hand to a high-throughput system for compound screening in pharmaceutical research and development. ■ Artificial Lipid Bilayer Experimental Device For functional and structural evaluation of target membrane proteins reconstituted into artificial lipid bilayers, as well as for evaluating drug actions. ■ Liposome Preparation Device Quickly and easily automates the preparation of liposomes without hassle. ■ Transporter Activity Measurement Device Enables label-free and real-time direct measurement of transporter currents without using fluorescent probes or radiolabeled ligands. ■ iPS-Derived Cardiomyocyte Measurement System For evaluating cardiotoxicity, contractility, and drug screening using iPS-derived cardiomyocytes. ■ Cell Monitoring Device Allows for label-free and real-time high-throughput measurement of cell kinetics (up to 6 x 96-well plates).

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Company information

ナニオンテクノロジーズジャパン

ナニオンテクノロジーズジャパン 東京ラボ(東京大学内)

Pharmaceuticals and Biotechnology

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Nanion Technologies is a scientific instrument manufacturer founded in 2002 in Munich, Germany, specializing in the automation of electrophysiology experiments. We enable the automation of electrophysiology experiments, supporting not only ion channel research but also a wide range of membrane protein-related studies. We offer a broad product lineup, including our industry-leading automated patch clamp system, transporter activity measurement systems, artificial lipid bilayer experimental devices, liposome production devices, and impedance, extracellular potential, and contraction force measurement systems for iPS-derived cardiomyocytes. These systems have been adopted by many universities, pharmaceutical companies, and research institutions both domestically and internationally, and are highly regarded. For inquiries about our products, requests for introductions, demo requests, or catalog requests, please contact us or our authorized distributors. Additionally, feel free to consult us about visiting our Tokyo lab (Meguro Ward) to see the systems and experiments. Mail: info@nanion.jp

Product/Service List (49)

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