Transglycosylation of IgG! It is possible to obtain antibody preparations with specific glycoforms!
TransGLYCIT is a platform technology for efficiently transglycosylating native human IgG within 3 hours. Using enzymatic remodeling, it enables the transglycosylation of N-linked glycans in the Fc region of antibodies, resulting in a robust workflow that allows for the preparation of antibody products with specific glycoforms. This technology is available in kit form for producing antibodies with G0, G1, G2, or G2S2 glycan profiles (± fucose), and there is also an option to remove fucose from the core GlcNAc using the TransGLYCIT Afucosylated kit. 【Features】 ■ Efficiently transglycosylate native human IgG within 3 hours ■ Allows for the preparation of antibody products with specific glycoforms ■ Available in kit form for producing antibodies with G0, G1, G2, or G2S2 glycan profiles (± fucose) ■ Option to remove fucose from the core GlcNAc is also available *For more details, please refer to the PDF document or feel free to contact us.
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【Product Format】 ■TransGLYCIT: Human IgG Glycan Remodeling (G0, G1, G2, G2S2) Kit ■TransGLYCIT Afucosylated Human IgG Glycan Remodeling (G0, G1, G2, G2S2 + De-fucosylation) Kit *For more details, please refer to the PDF document or feel free to contact us.
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For more details, please refer to the PDF document or feel free to contact us.
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