The success rate over the past three years boasts over 90% and has been adopted by many pharmaceutical companies.
For features 1 to 3, please refer to the seven characteristics of our monoclonal antibody production contract service. 4. Customization through molecular engineering It is possible to add various tags to antibodies or produce various fusion proteins. Additionally, dimerization can be achieved using a helix-turn-helix motif, which can enhance antigen cross-linking ability and improve affinity. 5. Abundant options As an option, we can also handle the preparation of antigens. Conversions to human IgG, IgA, or mouse chimeric IgG, as well as affinity enhancement after antibody production, increasing the number of candidate antibodies, and additional antibody preparations are possible. 6. No cost if ELISA-positive antibodies are not obtained Our service boasts a success rate of over 90%. Based on this confidence backed by our success rate, there will be no charge if ELISA-positive antibody clones are not obtained against the antigen. 7. Continuous supply of antibodies Antibodies are backed up in three formats: whole cells, plasmid DNA, and DNA sequence information, ensuring that all antibodies can be rapidly reproduced from these backups, guaranteeing a continuous supply. *Please feel free to contact us for more details.
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basic information
▼First, from Planning▼ The "Antibody Craftsman" monoclonal antibody production service begins with planning when we receive inquiries about antibody production from customers. To create antibodies suitable for the customer's intended use, we will ask about the characteristics of the antigen and the purpose of the antibody. Next, we will design the antigen according to the purpose of the antibody to be obtained and propose strategic selection methods tailored to the type of antigen and the intended use of the antibody, provided by experienced personnel throughout the entire process. ▼Format and Reproducibility of Delivered Antibodies▼ The antibodies produced will be in the form of Fab, and you can choose between monovalent or divalent options, as well as two types of tags, to be delivered in your desired format. The obtained antibodies will be purified as recombinant proteins from E. coli, allowing us to deliver them with the same quality repeatedly. Additionally, it is easy to convert Fab into immunoglobulin isotypes such as IgA, IgE, IgG, and IgM.
Price range
Delivery Time
※As short as 7 weeks from the receipt of the antigen.
Applications/Examples of results
Antibodies produced by "Antibody Craftsman" can be used in various applications just like antibodies produced by conventional methods. Furthermore, since they are Fab antibodies, they possess properties that can provide additional advantages in certain assay systems, such as not needing to remove the Fc region to prevent binding to receptors or to minimize the reaction of human anti-mouse antibodies (HAMA). Additionally, tag-specific detection antibodies are very useful in many applications.
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Company information
Gene Frontier has been expanding its business areas that contribute to the acceleration of biopharmaceuticals, including antibody drugs, and has been advancing the development of its unique technologies. Moving forward, we aim to accelerate our research and development and business development to achieve further growth on a global scale. We will continue to provide unique technologies and services for the development of innovative pharmaceuticals and diagnostic drugs, striving to be a trusted partner for our customers and contribute to 21st-century healthcare.