Unique Antibody Production Technology - HuCAL Technology
The Antibody Craftsman's monoclonal antibody production service utilizes unique technologies such as phage display, strategic antibody selection, and high-throughput processes to select specific Fab antibodies against various antigens. This process enables us to provide antibodies with specialized specificities tailored to our customers' needs and to prepare antibody formats in a short period. HuCAL PLATINUM Library The HuCAL PLATINUM, consisting of approximately 45 billion patterns, is the world's largest high-quality antibody library. This library is based on a combination of genes for complementarity-determining regions (CDRs) with high diversity and framework master genes, optimized for expression in E. coli. *For more details, please refer to the PDF materials or feel free to contact us.
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basic information
▼First, Planning▼ The "Antibody Craftsman" monoclonal antibody production service begins with planning when we receive inquiries about antibody production from our customers. To create antibodies suitable for the customer's intended use, we will ask about the characteristics of the antigen and the purpose of the antibody. Next, we will design the antigen according to the purpose of the antibody to be obtained and propose strategic selection methods tailored to the type of antigen and the intended use of the antibody, provided by experienced personnel throughout the entire process. ▼Format and Reproduction of Delivered Antibodies▼ The antibodies produced will be in the Fab format, and you can choose between monovalent or divalent options, as well as two types of tags, to be delivered in your desired format. The obtained antibodies will be purified as recombinant proteins from E. coli, allowing us to deliver them with the same quality repeatedly. Additionally, it is easy to convert Fab into immunoglobulin isotypes such as IgA, IgE, IgG, and IgM.
Price range
Delivery Time
※At the shortest, 7 weeks from the receipt of the antigen.
Applications/Examples of results
Antibodies produced by "Antibody Craftsman" can be used in various applications just like antibodies produced by conventional methods. Furthermore, since they are Fab antibodies, they possess properties that can provide additional advantages in certain assay systems, such as not needing to remove the Fc region to prevent binding to receptors or to minimize the reaction of human anti-mouse antibodies (HAMA). Additionally, tag-specific detection antibodies are very useful in many applications.
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Company information
Gene Frontier has been expanding its business areas that contribute to the acceleration of biopharmaceuticals, including antibody drugs, and has been advancing the development of its unique technologies. Moving forward, we aim to accelerate our research and development and business development to achieve further growth on a global scale. We will continue to provide unique technologies and services for the development of innovative pharmaceuticals and diagnostic drugs, striving to be a trusted partner for our customers and contribute to 21st-century healthcare.