Antibody Artisan Frequently Asked Questions Part 2: What is the difference from other phage display methods?
Question: What is the difference from other phage display methods? Answer: The concept and methods for creating the library are different. We analyze the structure and sequences of human antibodies and construct a high-quality library artificially synthesized from DNA according to the rules of human antibodies. *For more detailed information about the service, please refer to the PDF document or feel free to contact us.*
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basic information
▼First, from Planning▼ The "Antibody Craftsman" monoclonal antibody production service begins with planning when we receive inquiries from customers about antibody production. To create antibodies suitable for the customer's intended use, we will ask about the characteristics of the antigen and the purpose of the antibody. Next, we will design the antigen according to the purpose of the antibody to be obtained and propose strategic selection methods tailored to the type of antigen and the intended use of the antibody, provided by experienced personnel throughout the entire process. ▼Format and Reproduction of Delivered Antibodies▼ The antibodies produced will be in the form of Fab, and you can choose between monovalent or divalent options, as well as two types of tags, to be delivered in your desired format. The obtained antibodies will be purified as recombinant bodies from E. coli, allowing us to deliver the same quality repeatedly. Additionally, it is easy to convert Fab into immunoglobulin isotypes such as IgA, IgE, IgG, and IgM.
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Delivery Time
※At the earliest, 7 weeks from the receipt of the antigen.
Applications/Examples of results
Antibodies produced by "Antibody Craftsman" can be used in various applications just like antibodies produced by conventional methods. Furthermore, since they are Fab antibodies, they possess properties that can be advantageous in certain assay systems, such as eliminating the need to remove the Fc region to prevent binding to receptors or to minimize the reaction of human anti-mouse antibodies (HAMA). Additionally, tag-specific detection antibodies are very useful in many applications.
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Company information
Gene Frontier has been expanding its business areas that contribute to the acceleration of biopharmaceuticals, including antibody drugs, and has been advancing the development of its unique technologies. Moving forward, we aim to accelerate our research and development and business development to achieve further growth on a global scale. We will continue to provide unique technologies and services for the development of innovative pharmaceuticals and diagnostic drugs, striving to be a trusted partner for our customers and contribute to 21st-century healthcare.