An article introducing the selection of antibodies that distinguish specific proteins within family proteins.
Antibody artisans produce antibodies entirely in vitro without using animal immunization, allowing for detailed antigen design, such as narrowing down sequences and confirming cross-reactivity with different antigens during selection. In this case, we will introduce the antigen setup and selection method for producing antibodies that belong to a family of target proteins, binding only to the desired protein and not to other proteins within the same family. 【Contents】 ■1. Specificity of antibodies ■2. Preparation of antigens ・2-1. Design of antigens ・2-2. Production of conjugates ■3. Methods of selection ・3-1. Panning ・3-2. Screening ELISA ■4. Key points of selection ・4-1. Design of antigens ・4-2. Enhancing antibody specificity ■5. Summary *For detailed content of the article, please refer to the related links. *For detailed specifications, please refer to the PDF materials or feel free to contact us.
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*You can view the detailed content of the article through the related link. *For detailed specifications, please refer to the PDF document or feel free to contact us.
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Gene Frontier has been expanding its business areas that contribute to the acceleration of biopharmaceuticals, including antibody drugs, and has been advancing the development of its unique technologies. Moving forward, we aim to accelerate our research and development and business development to achieve further growth on a global scale. We will continue to provide unique technologies and services for the development of innovative pharmaceuticals and diagnostic drugs, striving to be a trusted partner for our customers and contribute to 21st-century healthcare.