Using Supel Swift HLB solid phase columns! It allows for efficient handling of compounds with various characteristics.
This document introduces the LC-MS analysis of serum samples using the Supel Swift HLB solid-phase column. The preparation of biological samples can significantly impact reproducibility and accuracy. Solid-phase extraction (SPE) helps reduce matrix effects such as ion suppression, contributing to the reliability of consistent results. In this study, we analyzed a mixture of 20 compounds from bovine serum with various log P values (-0.89 to 4.65) using the Supel Swift HLB solid-phase column. [Contents] ■ Background ■ Experimental Methods ■ Results and Discussion ■ Conclusion ■ Materials *For more details, please refer to the PDF document or feel free to contact us.
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From research and development of pharmaceuticals to manufacturing and diagnostics, Merck is working to solve various challenges in life sciences in collaboration with the global science community. Merck's products include over 300,000 items, ranging from laboratory pure and ultra-pure water systems to gene editing tools for drug manufacturing, antibodies, cell lines, and end-to-end systems. To realize promising research more quickly and safely, we closely collaborate with customers in academia, the biotechnology industry, and the pharmaceutical industry. Please feel free to contact us for inquiries about our products or if you are interested in raw material supply. Here is the Merck ultra-pure and pure water systems webpage → https://www.merckmillipore.com/LW Here is the Merck life science reagents, raw materials, and analysis webpage → https://www.sigmaaldrich.com/JP/ja