Useful for research on antibody-drug conjugates! It is possible to selectively deliver drugs to target cells.
"ADC LINKER" is a dipeptide linker used as a component of antibody-drug conjugates. When it binds to and is taken up by cells expressing the antigen recognized by the antibody, hydrolysis occurs between Cit-pAB by cathepsin B inside the cell. The drug that is bound is then released. As a result, it allows for selective action of the drug on the target cells. Please feel free to contact us if you have any inquiries. 【Features】 ■ Useful for research on antibody-drug conjugates ■ When it binds to and is taken up by cells expressing the antigen recognized by the antibody, hydrolysis occurs between Cit-pAB by cathepsin B inside the cell ■ The drug that is bound is released *For more details, please refer to the PDF materials or feel free to contact us.
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【Lineup】 ■Aloc-Val-Ala-pAB ■Aloc-Val-Cit-pAB ■Fmoc-Val-Ala-pAB ■Fmoc-Val-Cit-pAB *For more details, please refer to the PDF document or feel free to contact us.
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For more details, please refer to the PDF document or feel free to contact us.
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Since we started manufacturing and selling Boc-amino acids in 1982, we have gradually expanded our product offerings to include Z-amino acids, Fmoc-amino acids, and resins for solid-phase synthesis. Currently, we also sell special amino acids, non-natural amino acids, coupling agents, coupling additives, and solvents for peptide synthesis, providing a wide range of reagents related to peptide synthesis. We actively engage in contract synthesis of amino acid derivatives (both natural and non-natural) that are not listed in our catalog, as well as bulk supply of resins for solid-phase synthesis, short-chain peptides, and various compounds.