We would like to introduce a case study of hERG measurement using Patchliner.
Application Note: Effect of temperature on erythromycin action on hERG currents recorded on Nanion's Patchliner *For more details, please refer to the PDF document or feel free to contact us.*
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basic information
The tabletop dispensing device enables fully automated experiments. It is an auto patch clamp system capable of continuous measurement of up to 48 cells. This tabletop-sized auto patch clamp system can simultaneously measure up to 8 cells with giga-seal formation. With easy experimental setup, stable whole-cell recordings, and sophisticated software, it achieves highly efficient ion channel screening of compounds. ■ Equipped with a dispensing device for fully automated experiments (measurements) ■ Simultaneous measurement of 4 cells / 8 cells (continuous measurement of up to 48 cells) ■ 250–600 data points per day ■ Automation of giga-seal formation / whole-cell formation ■ Compatible with voltage-dependent and ligand-dependent channels ■ Measurement of action potentials using current clamp is also possible ■ Dynamic clamp available (optional) ■ Temperature control and extracellular/intracellular perfusion possible ■ Cooling plate allows for cooling of cells and compounds ■ Borosilicate glass chips reduce compound adsorption ■ Comes with excellent analysis software
Price range
Delivery Time
※The delivery time may vary depending on the stock status, so please feel free to contact us.
Applications/Examples of results
For more details, please refer to the PDF document or feel free to contact us. For inquiries about products, requests for demos, requests for catalogs, or any other inquiries, please feel free to contact us directly. Mail: info@nanion.jp
catalog（13）
Download All Catalogs![[Measurement Example] hERG | Patchliner](https://image.mono.ipros.com/public/catalog/image/01/b76/724362/IPROS27134965290401739379.jpeg?w=120&h=170)
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![[Measurement Example] NaV1.5 | Patchliner](https://image.mono.ipros.com/public/catalog/image/01/0b9/778886/IPROS38225543442795555702.jpeg?w=120&h=170)
![[Measurement Example] Dynamic Clamp | Patchliner](https://image.mono.ipros.com/public/catalog/image/01/358/778888/IPROS84341497954845338269.jpeg?w=120&h=170)
![[Measurement Example] TRPV3 | Patchliner](https://image.mono.ipros.com/public/catalog/image/01/8ae/778889/IPROS19379782253324174138.jpeg?w=120&h=170)
![[Measurement Example] nAChR | Patchliner](https://image.mono.ipros.com/public/catalog/image/01/f11/778891/IPROS71171923785321800834.jpeg?w=120&h=170)
![[Measurement Example] AMPA | Patchliner](https://image.mono.ipros.com/public/catalog/image/01/abf/778894/IPROS85277741424750145173.jpeg?w=120&h=170)
![[Measurement Example] PIEZO1 | Patchliner](https://image.mono.ipros.com/public/catalog/image/01/197/778896/IPROS79149000292822356740.jpeg?w=120&h=170)
![[Measurement Example] P2X | Patchliner](https://image.mono.ipros.com/public/catalog/image/01/962/778899/IPROS70850728717906518704.jpeg?w=120&h=170)
![[Measurement Example] Nav1.8 | Patchliner](https://image.mono.ipros.com/public/catalog/image/01/250/743621/IPROS56477721034708590536.jpeg?w=120&h=170)
Company information
Nanion Technologies is a scientific instrument manufacturer founded in 2002 in Munich, Germany, specializing in the automation of electrophysiology experiments. We enable the automation of electrophysiology experiments, supporting not only ion channel research but also a wide range of membrane protein-related studies. We offer a broad product lineup, including our industry-leading automated patch clamp system, transporter activity measurement systems, artificial lipid bilayer experimental devices, liposome production devices, and impedance, extracellular potential, and contraction force measurement systems for iPS-derived cardiomyocytes. These systems have been adopted by many universities, pharmaceutical companies, and research institutions both domestically and internationally, and are highly regarded. For inquiries about our products, requests for introductions, demo requests, or catalog requests, please contact us or our authorized distributors. Additionally, feel free to consult us about visiting our Tokyo lab (Meguro Ward) to see the systems and experiments. Mail: info@nanion.jp