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  6. 384ch Auto Patch Clamp SyncroPatch 384

384ch Auto Patch Clamp SyncroPatch 384

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SyncroPatch 384

last updated:Apr 30, 2025

ナニオンテクノロジーズジャパン 東京ラボ(東京大学内)
ナニオンテクノロジーズジャパン 東京ラボ(東京大学内)
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An automated patch clamp system capable of meeting all needs, from small-scale screening projects to high-throughput screening.

Designed to seamlessly integrate fully automated compound screening into the drug discovery process, it provides the best performance in high-throughput screening of ion channels in drug discovery, pharmacology, safety, pharmaceutical research and development, and exploratory screening departments. Additionally, by using the 32-well mode, it can be optimized for small-scale compound screening and projects. ■ Simultaneous measurement of 384 cells ■ 20,000 data points per day ■ High giga-seal success rate ■ Supports a variety of ion channel targets and enables rapid assay system development ■ Measurement of action potentials using current clamp is also possible ■ Extracellular/intracellular perfusion is possible ■ High-speed external solution exchange (up to 110 µl/s) is possible ■ Measurement section and 12 decks can be individually temperature controlled (temperature range: 10–37°C) ■ Compound plate preparation on the deck is possible ■ Single & multi-well chips available (in-house manufactured) ■ Borosilicate glass chips reduce compound adsorption ■ Approximately 8 hours of unmanned operation is possible ■ Comes with powerful analysis software ■ Validated system for CiPA

    Other physicochemical equipmentAnalytical EquipmentPatch clamp system
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384ch Auto Patch Clamp SyncroPatch 384

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basic information

The SyncroPatch 384 is a groundbreaking automated patch clamp system that integrates a patch clamp module with the state-of-the-art automated pipetting system Biomek i5. It enables simultaneous measurement of 384 cells, achieving a throughput of 20,000 data points per day. Its user-friendliness and open design support complete automation and integration into high-throughput screening (HTS). By utilizing the 32-well mode, it can cater to various throughput needs, not only for high-throughput screening but also for small-scale screening projects and academic research, maximizing the cost benefits of the NPC-384 chip. Users can select the number of wells required for experiments in units of 32 and use the remaining wells over several days. Additionally, by fully automating the program, experiments lasting about 8 hours can be conducted unattended. With its exceptional data quality and flexibility, the SyncroPatch 384 is adopted by global pharmaceutical companies, CROs, and academic institutions.

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Applications/Examples of results

We have numerous delivery achievements in the drug discovery, pharmacology, safety, pharmaceutical research and development, and exploratory screening departments of pharmaceutical companies, as well as with CROs, both domestically and internationally. *For more details, please refer to the PDF document or feel free to contact us. For inquiries regarding products, requests for demos, catalog requests, or any other inquiries, please feel free to contact us directly. Mail: info@nanion.jp

catalog(11)

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Comprehensive Catalog: Electrophysiology Experimental Equipment Catalog vol. 6

Comprehensive Catalog: Electrophysiology Experimental Equipment Catalog vol. 6

CATALOG
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384ch Auto Patch Clamp System SyncroPatch 384

384ch Auto Patch Clamp System SyncroPatch 384

PRODUCT
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【Cell and Ion Channel Measurement Example】 Auto Patch Clamp System

【Cell and Ion Channel Measurement Example】 Auto Patch Clamp System

TECHNICAL
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[Measurement Example] Nav1.5 | SyncroPatch 384i

[Measurement Example] Nav1.5 | SyncroPatch 384i

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[Measurement Example] TRP Channels | SyncroPatch 384

[Measurement Example] TRP Channels | SyncroPatch 384

TECHNICAL
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[Measurement Example] DRG Neurons | SyncroPatch 384

[Measurement Example] DRG Neurons | SyncroPatch 384

TECHNICAL
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[Measurement Example] TMEM175 | SyncroPatch 384

[Measurement Example] TMEM175 | SyncroPatch 384

TECHNICAL
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[Measurement Example] ASIC3 | SyncroPatch 384PE

[Measurement Example] ASIC3 | SyncroPatch 384PE

TECHNICAL
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[Measurement Example] HCN2 | SyncroPatch 384i

[Measurement Example] HCN2 | SyncroPatch 384i

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[Measurement Example] P2X3 and P2X2/3 Receptors | SyncroPatch 384

[Measurement Example] P2X3 and P2X2/3 Receptors | SyncroPatch 384

TECHNICAL
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Differences between Auto and Manual Patch Clamp

Differences between Auto and Manual Patch Clamp

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News about this product(19)

[Seminar Announcement] Membrane Physiology Symposium Japan 2026

  • Seminar・Event

We are pleased to announce that Nanion Technologies Japan Co., Ltd. will be hosting the "Membrane Physiology Symposium Japan 2026" in collaboration with Professor Hideaki Kato's laboratory at the University of Tokyo's Advanced Molecular Research Center and Cosmo Bio Co., Ltd. Please check the program and registration details from the link below. ■ Speakers Dr. Soki Hou | Tokyo University of Science, Faculty of Engineering, Mechanical Engineering Dr. Ai Nakajima | University of Tokyo, Graduate School of Pharmaceutical Sciences, Department of Pharmacology Dr. Hideaki Kato | University of Tokyo, Advanced Molecular Research Center Dr. Shin Iwagaki | Sumitomo Pharma Co., Ltd., CNS Drug Discovery Research Unit Dr. Azusa Seki | Axcelead Drug Discovery Partners Inc., Discovery Technologies BU Elisa Monz | 3Brain AG Catherine Elton | Axol Bioscience Ltd. Dr. Motohiro Nishida | Kyushu University, Graduate School of Pharmaceutical Sciences, Department of Physiology Søren Friis | Nanion Technologies GmbH

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[Workshop Announcement] Electrophysiology Experiment Workshop 2026

  • Seminar・Event

You can experience actual measurements and demonstrations using our various products. For more details about the products, please refer to the related products below. *Capacity: Approximately 10 to 20 people *Due to limited lab space, depending on the number of participants, there may be a possibility of dividing the sessions into two parts: morning and afternoon. *Participants who register for the workshop will be contacted again once the details are finalized. Please check the following for registration details and application.

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[Exhibition Information] 17th Annual Meeting of the Japanese Society of Safety Pharmacology

  • Seminar・Event

We would like to inform you that we will be exhibiting at the 17th Annual Meeting of the Japanese Society of Safety Pharmacology. If you are planning to attend, please be sure to stop by. ❚ 17th Annual Meeting of the Japanese Society of Safety Pharmacology Date: February 26 (Thursday) - February 27 (Friday), 2026 Venue: Sonic City (Saitama Prefecture) Exhibition Booth: 10 For more details, please visit the official website of the Japanese Society of Safety Pharmacology. ❚ Products to be exhibited - Automated Patch Clamp System | Port-a-Patch | Port-a-Patch mini - iPS-Derived Cardiomyocyte Measurement Device | CardioExcyte 96 | FLEXcyte 96 Regarding the Automated Patch Clamp System, we can introduce the "Patchliner," which eliminates the need for pipetting during experiments, is a benchtop model equipped with a dispensing device, and allows for fully automated continuous measurement of up to 48 cells. Additionally, we can also present the "SyncroPatch 384," which is adopted by the U.S. FDA and can accommodate a wide range of needs from small-scale screening projects to high-throughput screening (HTS).

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[Workshop Announcement] Electrophysiology Experiment Workshop 2025

  • Seminar・Event

You can experience actual measurements and demonstrations using our various products. For more details about the products, please refer to the related products below. *Capacity: Approximately 10 to 20 people *Due to limited lab space, depending on the number of participants, there may be a possibility of dividing into two sessions, morning and afternoon. *Participants who register for the workshop will be contacted again once the details are finalized.

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Companynews list (54)

Company information

ナニオンテクノロジーズジャパン

ナニオンテクノロジーズジャパン 東京ラボ(東京大学内)

Pharmaceuticals and Biotechnology

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Phone number/address

Nanion Technologies is a scientific instrument manufacturer founded in 2002 in Munich, Germany, specializing in the automation of electrophysiology experiments. We enable the automation of electrophysiology experiments, supporting not only ion channel research but also a wide range of membrane protein-related studies. We offer a broad product lineup, including our industry-leading automated patch clamp system, transporter activity measurement systems, artificial lipid bilayer experimental devices, liposome production devices, and impedance, extracellular potential, and contraction force measurement systems for iPS-derived cardiomyocytes. These systems have been adopted by many universities, pharmaceutical companies, and research institutions both domestically and internationally, and are highly regarded. For inquiries about our products, requests for introductions, demo requests, or catalog requests, please contact us or our authorized distributors. Additionally, feel free to consult us about visiting our Tokyo lab (Meguro Ward) to see the systems and experiments. Mail: info@nanion.jp

Product/Service List (49)

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