Tohoku University Technology: Biomaterial and its manufacturing method: T19-380
Able to maintain excellent antibacterial properties for a long time!
Biomaterials such as artificial joints are made of Ti (titanium), which can adhere directly to the bone. It is known that biomaterials can be coated with ACP film (amorphous calcium phosphate) to improve osteogenic potential. However, ACP film dissolves in vivo in a short period of time, so the improvement is required to retain for a long time. One idea is to add Ta (tantalum) to prevent dissolution but this method does not have antibacterial properties. It is possible to add Ag (silver) to the ACP film to give antibacterial properties, but the dissolution is not possible to control. This invention is about a biomaterial and its manufacturing method that can prevent the ACP film dissolution of the surface while having excellent antibacterial properties. The biomaterial is characterized by an ACP film with Ag and Ta dopped on the substrate surface. The coating film is formed by RF magnetron sputtering method. The addition of Ta suppresses the ACP film dissolution while having an excellent antibacterial properties due to the Ag addition. This invention has made possible to sustain an excellent antimicrobial properties over a long period of time.
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The revenue generated from technology transfer is reinvested as new research funding for universities and researchers, and is utilized to create further research outcomes. To ensure the smooth operation of this cycle, known as the "Intellectual Creation Cycle," we will vigorously promote technology transfer. The types of seeds we handle include patents, know-how, databases, and programs. We have established a collaborative framework by signing basic technology transfer agreements with the following universities (as of June 1, 2025): Tohoku University, Hirosaki University, Iwate University, Akita University, Fukushima University, Yamagata University, Tohoku Gakuin University, Iwate Medical University, Fukushima Medical University, Aizu University, Miyagi University, Hokkaido University, Muroran Institute of Technology, and Showa Medical University.



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