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  6. Handbook "Utilization of Valves in Aseptic Environments" - From Pump Combination Examples to More -

Handbook "Utilization of Valves in Aseptic Environments" - From Pump Combination Examples to More -

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last updated:Nov 17, 2025

Nikuni Co., Ltd.
Nikuni Co., Ltd.
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Introducing examples of problem-solving in a sterile environment using valves and pumps. Contributing to the automation and reduced maintenance of filling and cleaning in industries such as pharmaceuticals and semiconductors.

This document introduces the utilization of valves and pumps suitable for aseptic environments in the food and beverage, pharmaceutical and cosmetic, and chemical and semiconductor industries. Focusing on the four features of "aseptic valves"—durability, cleanliness, compactness, and operability—this document provides information that aids in maintaining aseptic environments and automating and reducing labor in cleaning processes. If you are interested in keywords such as small-bag filling at low flow rates, low-temperature filling, automatic cleaning with CIP/SIP, automation, and improved maintenance, please take a look. [Contents] ■ Four features of aseptic valves ■ Examples of using aseptic valves and Nikuni pumps (filling, low-temperature filling, sterilizers, etc.) ■ Specifications of aseptic valves ■ Introduction of related products *For more details, please refer to the document available for download as a PDF. Feel free to contact us with any inquiries.

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Handbook "Utilization of Valves in Aseptic Environments" - From Pump Combination Examples to More -

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  • Related Link - https://www.nikuni.co.jp/product/114_index_detail.…
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**Challenges that can be solved by utilizing valves and pumps** Filling: At low flow rates, there is a high leakage amount when pumping water or low-viscosity liquids, leading to a lack of accuracy in measurement. It is difficult to maintain the required pumping pressure. Low-temperature filling: Filling containers or food items that are sensitive to high temperatures requires a low-temperature and sterile environment. Sterilizer: High pressure, large flow rate, and high temperature are necessary during CIP cleaning. A separate cleaning pump is required in addition to the material transfer pump. *For more details, please refer to the materials available for download in the PDF.*

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Handbook "Utilization of Valves in Aseptic Environments" - From Valves to Examples of Pump Combinations.

Handbook "Utilization of Valves in Aseptic Environments" - From Valves to Examples of Pump Combinations.

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Nikuni

Nikuni Co., Ltd.

Machine elements and parts

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Nikuni Co., Ltd. is a company (manufacturer) engaged in the development, production, and sales of pumps. In particular, we focus on the development, production, and sales of products centered around vortex turbine pumps, as well as the development, production, and sales of devices that improve the environment within factories by incorporating pumps (such as coolant systems and filtration systems). Pumps are the heart of devices and equipment. As a precision machinery manufacturer, Nikuni has been producing high-precision, high-quality components for many years. Utilizing our machining technology, Nikuni produces pumps with precision that exceeds the norms of general pumps (such as perpendicularity, parallelism, concentricity, and runout), resulting in pumps that pursue high precision and high quality. To prevent issues, we conduct a full inspection of all pumps before shipment, ensuring that only those that meet Nikuni's quality standards are shipped. Nikuni manufactures and sells products so that everyone involved with pumps can use them with confidence.

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