You can provide a list of validated targets for the transporter activity measurement device SURFE²R.
Can you provide the list of validated targets for the transporter activity measurement device SURFE²R? *For more details, please refer to the PDF document or feel free to contact us.*
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basic information
Currently, the mainstream method for evaluating transporter activity is the uptake assay using RI-labeled substrates. However, there are several issues, such as the need for specialized experimental facilities, the complexity of waste liquid treatment, the fact that the desired substrates are not always commercially available as RI-labeled, and the measurement of endpoints after uptake. SURFE²R (Surface Electrogenic Event Reader) technology does not require RI labeling, does not need specialized experimental facilities or waste liquid treatment, and allows for real-time evaluation of the activity of transporters (symporters, exchangers, unipoters) and pumps. - Direct measurement of transporter currents using Solid Supported Membrane (SSM) - Experiments can be conducted using membrane fragments prepared from biological membranes or proteoliposomes reconstituted with the target membrane proteins - Light stimulation is possible (optional) - An all-in-one device that integrates a dispensing machine, measurement section, and computer - 150 data points per day
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Applications/Examples of results
For more details, please refer to the PDF document or feel free to contact us. For inquiries about products, requests for demos, requests for catalogs, or any other inquiries, please feel free to contact us directly. Mail: info@nanion.jp
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![[Measurement Example] TMEM175 | SURFE²R 96SE](https://image.mono.ipros.com/public/catalog/image/01/f7a/774439/IPROS51780279639621834739.jpeg?w=120&h=170)
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Company information
Nanion Technologies is a scientific instrument manufacturer founded in 2002 in Munich, Germany, specializing in the automation of electrophysiology experiments. We enable the automation of electrophysiology experiments, supporting not only ion channel research but also a wide range of membrane protein-related studies. We offer a broad product lineup, including our industry-leading automated patch clamp system, transporter activity measurement systems, artificial lipid bilayer experimental devices, liposome production devices, and impedance, extracellular potential, and contraction force measurement systems for iPS-derived cardiomyocytes. These systems have been adopted by many universities, pharmaceutical companies, and research institutions both domestically and internationally, and are highly regarded. For inquiries about our products, requests for introductions, demo requests, or catalog requests, please contact us or our authorized distributors. Additionally, feel free to consult us about visiting our Tokyo lab (Meguro Ward) to see the systems and experiments. Mail: info@nanion.jp