[Exhibition Information] 19th Annual Transporter Research Conference

Direct measurement of transporter currents in a label-free and real-time manner without using fluorescent probes or radiolabeled ligands.

Currently, the mainstream method for evaluating transporter activity is the uptake assay using RI-labeled substrates. However, there are several issues, such as the need for specialized experimental facilities, the complexity of waste liquid treatment, the fact that the desired substrates are not always commercially available as RI-labeled, and the measurement of endpoints after uptake. SURFE²R (Surface Electrogenic Event Reader) technology does not require RI labeling, specialized experimental facilities, or waste liquid treatment, and it allows for real-time evaluation of the activity of transporters (symporters, exchangers, unipoters) and pumps. ■ Direct measurement of transporter currents using Solid Supported Membrane (SSM) ■ Experiments can be conducted using membrane fragments prepared from biological membranes or proteoliposomes reconstituted with the target membrane proteins ■ Light stimulation is possible (optional) ■ An all-in-one device that integrates a dispensing machine, measurement section, and computer ■ 150 data points per day

• Other physicochemical equipment
• Analytical Equipment
• Other Analysis

Direct measurement of transporter currents in a label-free and real-time manner without using fluorescent probes or radiolabeled ligands.

Currently, the mainstream method for evaluating transporter activity is the uptake assay using RI-labeled substrates. However, there are several issues, such as the need for specialized experimental facilities, complicated waste disposal processes, the fact that the desired substrates are not always commercially available as RI-labeled, and that the endpoint is measured after uptake. The SURFE²R (Surface Electrogenic Event Reader) technology does not require RI labeling, does not need specialized experimental facilities or waste disposal, and allows for real-time evaluation of the activity of transporters (symporters, exchangers, unipoters) and pumps. ■ Direct measurement of transporter currents using Solid Supported Membrane (SSM) ■ Experiments can be conducted using membrane fragments prepared from biological membranes or proteoliposomes reconstituted with the target membrane proteins ■ Simultaneous measurement in 96 wells ■ 10,000 data points per day

• Other physicochemical equipment
• Analytical Equipment
• Other Analysis

You can provide a list of validated targets for the transporter activity measurement device SURFE²R.

Can you provide the list of validated targets for the transporter activity measurement device SURFE²R? *For more details, please refer to the PDF document or feel free to contact us.*

• Other physicochemical equipment
• Analytical Equipment
• Other Analysis

Nanion Technologies realizes the automation of electrophysiology experiments and supports a wide range of membrane protein-related research.

**Catalog Products** ■ Auto Patch Clamp System Ideal for evaluating the effects of compounds on ion channels and for functional and structural analysis of ion channels. From a compact system that allows you to check data immediately at hand to high-throughput systems for compound screening in pharmaceutical research and development. ■ Artificial Lipid Bilayer Experimental Device For functional and structural evaluation of target membrane proteins reconstituted into artificial lipid bilayers, as well as for evaluating drug actions. ■ Liposome Preparation Device Quickly and easily automates the preparation of liposomes without hassle. ■ Transporter Activity Measurement Device Enables label-free and real-time direct measurement of transporter currents without using fluorescent probes or radiolabeled ligands. ■ iPS-Derived Cardiomyocyte Measurement System For assessing cardiotoxicity, contractility, and drug screening using iPS-derived cardiomyocytes. ■ Cell Monitoring Device Allows for label-free and real-time high-throughput measurement of cell kinetics (up to 6 x 96-well plates).

• Analytical Equipment
• Patch clamp system
• Other Analysis

We want to improve our operations with AI, but what exactly can we do... For those who want to actually try out and compare services, we have an announcement. The electronic contract and document management service paperlogic will be exhibiting at the 'Business Innovation Fair 2025 Autumn in Makuhari' hosted by Otsuka Shokai on November 13th (Thursday) and 14th (Friday) at the Hotel Green Tower Makuhari. Seminars on business improvement and AI utilization will also be held, so if you are nearby, please come and visit us. ● We will also be conducting product demonstrations of paperlogic at the venue. The biggest feature of paperlogic is that it is easy to use and simple, yet it complies with all document management regulations, including the Electronic Bookkeeping Act. We invite you to experience this simplicity firsthand.

What should we start with for the digital transformation (DX) in the quality assurance department? ■ Transitioning from manual input to automatic input for inspection sheet creation! ■ Connecting measurement result input tasks to digital calipers for automatic judgment! We propose to not only maximize the use of CAD drawings to streamline inspection operations but also to initiate the digital transformation starting from inspection tasks.

The electric actuator manufacturer LINAK will be exhibiting for the first time at the "International Robot Exhibition (iREX 2025)" held at Tokyo Big Sight. This exhibition is highly regarded both domestically and internationally as "one of the largest robot specialized exhibitions in the world." At the venue, we plan to showcase our lifting column "LC3 IC Elevate," which is suitable for lifting applications with collaborative robots, as well as electric cylinder solutions for AGV/AMR. We will propose sustainable and flexible automation solutions. Please be sure to visit our booth.

Fuji Chemical Co., Ltd. will be exhibiting at the "39th Hokkaido Business EXPO" held at Access Sapporo. This exhibition is one of the largest business events in Hokkaido. We plan to showcase GRP pipes for wastewater, pipes for hot springs, and pipes for plants. We sincerely look forward to your visit.

Fujikako Co., Ltd. will be exhibiting at the "17th International Food Trade Fair Food Messe in Niigata 2025," held at the Toki Messe Niigata Convention Center. This exhibition is an "International Comprehensive Food Trade Fair" that creates new value from tradition to advanced trends, bringing together participants from across the country to Niigata and from Niigata to the nation. We plan to showcase our Fuji GRP pipes for wastewater. We sincerely look forward to your visit.