[Exhibition Information] 19th Annual Transporter Research Conference

Direct measurement of transporter currents in a label-free and real-time manner without using fluorescent probes or radiolabeled ligands.

Currently, the mainstream method for evaluating transporter activity is the uptake assay using RI-labeled substrates. However, there are several issues, such as the need for specialized experimental facilities, the complexity of waste liquid treatment, the fact that the desired substrates are not always commercially available as RI-labeled, and the measurement of endpoints after uptake. SURFE²R (Surface Electrogenic Event Reader) technology does not require RI labeling, specialized experimental facilities, or waste liquid treatment, and it allows for real-time evaluation of the activity of transporters (symporters, exchangers, unipoters) and pumps. ■ Direct measurement of transporter currents using Solid Supported Membrane (SSM) ■ Experiments can be conducted using membrane fragments prepared from biological membranes or proteoliposomes reconstituted with the target membrane proteins ■ Light stimulation is possible (optional) ■ An all-in-one device that integrates a dispensing machine, measurement section, and computer ■ 150 data points per day

• Other physicochemical equipment
• Analytical Equipment
• Other Analysis

Direct measurement of transporter currents in a label-free and real-time manner without using fluorescent probes or radiolabeled ligands.

Currently, the mainstream method for evaluating transporter activity is the uptake assay using RI-labeled substrates. However, there are several issues, such as the need for specialized experimental facilities, complicated waste disposal processes, the fact that the desired substrates are not always commercially available as RI-labeled, and that the endpoint is measured after uptake. The SURFE²R (Surface Electrogenic Event Reader) technology does not require RI labeling, does not need specialized experimental facilities or waste disposal, and allows for real-time evaluation of the activity of transporters (symporters, exchangers, unipoters) and pumps. ■ Direct measurement of transporter currents using Solid Supported Membrane (SSM) ■ Experiments can be conducted using membrane fragments prepared from biological membranes or proteoliposomes reconstituted with the target membrane proteins ■ Simultaneous measurement in 96 wells ■ 10,000 data points per day

• Other physicochemical equipment
• Analytical Equipment
• Other Analysis

You can provide a list of validated targets for the transporter activity measurement device SURFE²R.

Can you provide the list of validated targets for the transporter activity measurement device SURFE²R? *For more details, please refer to the PDF document or feel free to contact us.*

• Other physicochemical equipment
• Analytical Equipment
• Other Analysis

Nanion Technologies realizes the automation of electrophysiology experiments and supports a wide range of membrane protein-related research.

**Catalog Products** ■ Auto Patch Clamp System Ideal for evaluating the effects of compounds on ion channels and for functional and structural analysis of ion channels. From a compact system that allows you to check data immediately at hand to high-throughput systems for compound screening in pharmaceutical research and development. ■ Artificial Lipid Bilayer Experimental Device For functional and structural evaluation of target membrane proteins reconstituted into artificial lipid bilayers, as well as for evaluating drug actions. ■ Liposome Preparation Device Quickly and easily automates the preparation of liposomes without hassle. ■ Transporter Activity Measurement Device Enables label-free and real-time direct measurement of transporter currents without using fluorescent probes or radiolabeled ligands. ■ iPS-Derived Cardiomyocyte Measurement System For assessing cardiotoxicity, contractility, and drug screening using iPS-derived cardiomyocytes. ■ Cell Monitoring Device Allows for label-free and real-time high-throughput measurement of cell kinetics (up to 6 x 96-well plates).

• Analytical Equipment
• Patch clamp system
• Other Analysis

We will be exhibiting at "Mechatrotech (or Monozukuri World)" held at Port Messe Nagoya (Nagoya International Exhibition Hall). During the event, we will showcase various products. We invite all related parties to come and visit us. 【Suppliers】 - Pferd - DC Swiss - Ensitec - Erichsen (Sheet metal) - EPK (if space allows) - Pipetite (if space allows)

We would like to extend our heartfelt congratulations on the continued prosperity of your esteemed company. Our company will be exhibiting at the following trade show, where we will introduce a number of products, including our new product, the Pillow Packaging Full Air Tightness Inspection Machine MSQ-2003. We sincerely apologize for the inconvenience during your busy schedule, but we would like to invite you to visit us at this opportunity. 【 Exhibition Name 】 JAPAN PACK 2025 Japan Packaging Industry Exhibition https://www.japanpack.jp/ 【 Dates 】 October 7 (Tuesday) to October 10 (Friday), 2025 *4 days 10:00 AM to 5:00 PM 【 Venue / Booth Number 】 Tokyo Big Sight / East Hall 8, Booth 8-505

Our company will be exhibiting at the "14th Fukushima Renewable Energy Industry Fair (REIF Fukushima 2025)" held at Big Palette Fukushima from Thursday, October 16, 2025, to Friday, October 17, 2025. Focusing on energy visualization solutions that can be started "immediately," we will introduce power monitoring solutions for each equipment and load through examples of the overall system configuration. 【Main Exhibited Products】 - Gateway BOX We will showcase the "Gateway BOX," a product that packages the necessary equipment for easy adoption of the visualization system. - PAL-Plus type E2 (Scheduled for release soon) We will introduce a "smart" clamp CT that can easily measure power for three-phase three-wire and single-phase three-wire systems (scheduled for release soon). - CEW-M4 / PAL-Plus As a monitoring system that can display power consumption and remaining power capacity, we will present the manager software "CEW-M4," which supports up to 20,000 points, and the Modbus-compatible AC current sensor "PAL-Plus." We sincerely look forward to your visit.

Toyo Machinery Co., Ltd. will be exhibiting at the high-performance film exhibition held at Makuhari Messe. The High-Performance Film Exhibition - FILMTECH JAPAN - is a specialized exhibition where molding processing technologies, materials, and functional films themselves are showcased all in one place. Experts from various fields, including the technology departments of film manufacturers, electronics, automotive, batteries, construction and building materials, and food and beverages, will attend in search of functional films. At Toyo Machinery, we will display actual machines for waviness correction and wrinkle removal while running film, allowing you to see their effects and functions. We will also introduce the quality management system (weight, thickness, moisture, etc.) from the German company Marlo. ↓↓↓Toyo Machinery's exhibitor information↓↓↓ https://www.material-expo.jp/tokyo/ja-jp/search/2025/directory/details.org-a11cd7f5-2a7b-4ea7-85ce-cde885acd2dd.html#/ *If you wish to attend, you can pre-register via the "Details & Application" link below. We sincerely look forward to your visit.

We will be exhibiting at the Okayama Technology Exhibition (OTEX) 2025, which will be held at Convex Okayama from November 12 (Wednesday) to November 13 (Thursday), 2025. We will showcase our eco-board pallets (paper pallets) as well as comprehensive packaging solutions suitable for one-way shipments such as exports. Our products will assist in addressing challenges related to environmental considerations in the context of the SDGs and the promotion of white logistics. ■ Our booth: 46 (Company products) We sincerely look forward to your visit, and we hope you can come together.