[Exhibition Information] 19th Annual Transporter Research Conference

Direct measurement of transporter currents in a label-free and real-time manner without using fluorescent probes or radiolabeled ligands.

Currently, the mainstream method for evaluating transporter activity is the uptake assay using RI-labeled substrates. However, there are several issues, such as the need for specialized experimental facilities, the complexity of waste liquid treatment, the fact that the desired substrates are not always commercially available as RI-labeled, and the measurement of endpoints after uptake. SURFE²R (Surface Electrogenic Event Reader) technology does not require RI labeling, specialized experimental facilities, or waste liquid treatment, and it allows for real-time evaluation of the activity of transporters (symporters, exchangers, unipoters) and pumps. ■ Direct measurement of transporter currents using Solid Supported Membrane (SSM) ■ Experiments can be conducted using membrane fragments prepared from biological membranes or proteoliposomes reconstituted with the target membrane proteins ■ Light stimulation is possible (optional) ■ An all-in-one device that integrates a dispensing machine, measurement section, and computer ■ 150 data points per day

• Other physicochemical equipment
• Analytical Equipment
• Other Analysis

Direct measurement of transporter currents in a label-free and real-time manner without using fluorescent probes or radiolabeled ligands.

Currently, the mainstream method for evaluating transporter activity is the uptake assay using RI-labeled substrates. However, there are several issues, such as the need for specialized experimental facilities, complicated waste disposal processes, the fact that the desired substrates are not always commercially available as RI-labeled, and that the endpoint is measured after uptake. The SURFE²R (Surface Electrogenic Event Reader) technology does not require RI labeling, does not need specialized experimental facilities or waste disposal, and allows for real-time evaluation of the activity of transporters (symporters, exchangers, unipoters) and pumps. ■ Direct measurement of transporter currents using Solid Supported Membrane (SSM) ■ Experiments can be conducted using membrane fragments prepared from biological membranes or proteoliposomes reconstituted with the target membrane proteins ■ Simultaneous measurement in 96 wells ■ 10,000 data points per day

• Other physicochemical equipment
• Analytical Equipment
• Other Analysis

You can provide a list of validated targets for the transporter activity measurement device SURFE²R.

Can you provide the list of validated targets for the transporter activity measurement device SURFE²R? *For more details, please refer to the PDF document or feel free to contact us.*

• Other physicochemical equipment
• Analytical Equipment
• Other Analysis

Nanion Technologies realizes the automation of electrophysiology experiments and supports a wide range of membrane protein-related research.

**Catalog Products** ■ Auto Patch Clamp System Ideal for evaluating the effects of compounds on ion channels and for functional and structural analysis of ion channels. From a compact system that allows you to check data immediately at hand to high-throughput systems for compound screening in pharmaceutical research and development. ■ Artificial Lipid Bilayer Experimental Device For functional and structural evaluation of target membrane proteins reconstituted into artificial lipid bilayers, as well as for evaluating drug actions. ■ Liposome Preparation Device Quickly and easily automates the preparation of liposomes without hassle. ■ Transporter Activity Measurement Device Enables label-free and real-time direct measurement of transporter currents without using fluorescent probes or radiolabeled ligands. ■ iPS-Derived Cardiomyocyte Measurement System For assessing cardiotoxicity, contractility, and drug screening using iPS-derived cardiomyocytes. ■ Cell Monitoring Device Allows for label-free and real-time high-throughput measurement of cell kinetics (up to 6 x 96-well plates).

• Analytical Equipment
• Patch clamp system
• Other Analysis

[Lecturer] Professor Hiroyuki Kato, Faculty of Sociology, Department of Social Policy Science, Hosei University [Key Lecture Content] In this lecture, I will introduce perspectives on the shipbuilding industry. Japan's shipbuilding industry has a long history and can be seen as a "microcosm" of Japanese industry. Within about ten years after World War II, Japan's shipbuilding industry became the world leader in construction volume, and at one point, the construction volume of the seven major domestic companies accounted for more than half of the world's share. Although it has since been surpassed in construction volume by latecomers such as South Korea and China, it still maintains a certain level of competitiveness. Reflecting on the path taken by the shipbuilding industry, which serves as a "microcosm," the reasons for its continued strength, and the challenges it currently faces may provide insights when considering the future of various Japanese industries. [Lecture Items] 1. Characteristics of the shipbuilding industry 2. Shipyards seen through photos and videos 3. The shipbuilding industry depicted in films 4. Why is it still strong? 5. Points to consider for future developments 6. Q&A / Business card exchange

[Speaker] Maho Tanaka, Manager, Strategy Group, Business Consulting Division, Accenture Japan Ltd. [Key Lecture Content] AI is evolving beyond a mere tool for operational efficiency to become an entity responsible for execution, including information acquisition, comparison, judgment, contracts, and purchasing. As actions initiated by dialogues with general-purpose AI chatbots like ChatGPT become mainstream, corporate information is not reaching users directly, and the structure where decision-making and execution are completed on AI is rapidly expanding. In this lecture, based on this irreversible change, we will organize the reality that the competitive axis of companies is shifting from "appealing to consumers" to "how AI understands, selects, and executes." Furthermore, we will explain the key points of strategic transformation that management should consider in the era of agent-based AI, from organizing the information structure cited by AI to designing touchpoints that reclaim the initiative for judgment and execution for the company. [Lecture Items] 1. The impact of AI on information search and access 2. The impact on corporate marketing and communication 3. The ideal direction for corporate communication in the AI era 4. Introduction of our company’s case studies 5. Q&A session

The overall theme of the webinar is: "The Two Barriers Hindering Automation in Food Factories" "Case Studies on Access Control and AI Image Recognition" Our company will be the first to present. For more details, please visit our website!

[Speaker] Yuki Kobayashi, CEO/Co-Founder of MESON Inc. [Key Lecture Content] In this presentation, we will explore "AI glasses," which have recently begun to attract significant attention as the next-generation user interface, explaining their essence and business impact. We will clarify the differences from previous XR devices and organize representative products currently available, while interpreting why AI glasses are becoming a realistic option against the backdrop of the evolution of generative AI and changes in societal acceptance. Furthermore, through market expansion and case studies primarily overseas, we will demonstrate why the years 2026 to 2028 will be a turning point for technology and business, and discuss the issues and risks that Japanese companies should currently address. [Lecture Items] 1. What are AI glasses? 2. Why AI glasses now? 3. Changes happening globally 4. How AI glasses will change work 5. Experience design as a decisive factor 6. The turning point for Japanese companies (Closing) 7. Q&A / Business card exchange *The content of the lecture may change based on the latest trends.

[Speaker] Andy Mochizuki, Director, Deloitte Tohmatsu TMT Division / Monitor Deloitte [Key Lecture Content] In an era where thinking is commoditized by AI, the source of value is determined not by "information" but by "existence," that is, "the meaning of your being." This course will start from the environmental changes surrounding the AI era, exploring the concept of redesigning work in a purpose-driven manner, the type of thinking required in the AI era (QADI cycle), and delving into the absolute differentiating factor that only humans possess—"embodiment." We will update our sense of purpose in the AI era and our collaborative relationship with AI, initiating a transformation to "live anew" from here. [Lecture Items] 1. Mapping Environmental Changes - "From the Era of Information Asymmetry to the Era of Existence Asymmetry" 2. Redesigning Work in a "Purpose-Driven" Manner 3. The "Thinking Models" Necessary in the AI Era 4. The "Body" as an Absolute Differentiating Factor 5. How to "Live Anew" in the Coming AI Era 6. Q&A / Business Card Exchange