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  6. [Measurement Example] TMEM175 | SyncroPatch 384

[Measurement Example] TMEM175 | SyncroPatch 384

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SyncroPatch 384

last updated:Apr 30, 2025

ナニオンテクノロジーズジャパン 東京ラボ(東京大学内)
ナニオンテクノロジーズジャパン 東京ラボ(東京大学内)
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We will introduce a case study of TMEM175 measurement using SyncroPatch.

Application Note: High throughput organellar electrophysiology of TMEM175 and TPC2 from freshly isolated lysosomes recorded on the SyncroPatch 384 *For more details, please refer to the PDF document or feel free to contact us.

    Other physicochemical equipmentAnalytical EquipmentPatch clamp system
測定事例_2.jpg

[Measurement Example] TMEM175 | SyncroPatch 384

測定事例_2.jpg
測定事例_2.jpg

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basic information

Designed to seamlessly integrate fully automated compound screening into the drug discovery process, it offers the best performance in high-throughput screening of ion channels within the drug discovery, pharmacology, safety, pharmaceutical research and development, and exploratory screening departments. Additionally, by utilizing the 32-well mode, it can be optimized for small-scale compound screening and projects. ■ Simultaneous measurement of 384 cells ■ 20,000 data points per day ■ High giga-seal success rate ■ Compatible with diverse ion channel targets, enabling rapid assay development ■ Measurement of action potentials via current clamp is also possible ■ Extracellular/intracellular perfusion capability ■ High-speed external solution exchange (up to 110 µl/s) ■ Individual temperature control for the measurement section and 12 decks (temperature range: 10–37°C) ■ Compound plate preparation on the deck ■ Use of single & multi-well chips (in-house manufactured) ■ Borosilicate glass chips reduce compound adsorption ■ Approximately 8 hours of unmanned operation possible ■ Comes with powerful analysis software ■ Validated system for CiPA

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Applications/Examples of results

For more details, please refer to the PDF document or feel free to contact us. For inquiries about products, requests for demos, requests for catalogs, or any other inquiries, please feel free to contact us directly. Mail: info@nanion.jp

catalog(10)

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[Measurement Example] DRG Neurons | SyncroPatch 384

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[Measurement Example] P2X3 and P2X2/3 Receptors | SyncroPatch 384

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[Measurement Example] TMEM175 | SyncroPatch 384

[Measurement Example] TMEM175 | SyncroPatch 384

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[Measurement Example] TRP Channels | SyncroPatch 384

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Comprehensive Catalog: Electrophysiology Experimental Equipment Catalog vol. 6

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Company information

ナニオンテクノロジーズジャパン

ナニオンテクノロジーズジャパン 東京ラボ(東京大学内)

Pharmaceuticals and Biotechnology

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Nanion Technologies is a scientific instrument manufacturer founded in 2002 in Munich, Germany, specializing in the automation of electrophysiology experiments. We enable the automation of electrophysiology experiments, supporting not only ion channel research but also a wide range of membrane protein-related studies. We offer a broad product lineup, including our industry-leading automated patch clamp system, transporter activity measurement systems, artificial lipid bilayer experimental devices, liposome production devices, and impedance, extracellular potential, and contraction force measurement systems for iPS-derived cardiomyocytes. These systems have been adopted by many universities, pharmaceutical companies, and research institutions both domestically and internationally, and are highly regarded. For inquiries about our products, requests for introductions, demo requests, or catalog requests, please contact us or our authorized distributors. Additionally, feel free to consult us about visiting our Tokyo lab (Meguro Ward) to see the systems and experiments. Mail: info@nanion.jp

Product/Service List (49)

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