We will introduce a case study of nAChR measurement using Patchliner.
Application Note: Nicotinic α3β4 receptors recorded on Nanion's Patchliner *For more details, please refer to the PDF document or feel free to contact us.
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basic information
The tabletop dispensing device enables fully automated experiments. It is an auto patch clamp system capable of continuous measurement of up to 48 cells. This tabletop-sized auto patch clamp system can simultaneously measure up to 8 cells that have formed gigaohm seals. With easy experimental setup, stable whole-cell recordings, and sophisticated software, it achieves highly efficient ion channel screening for compounds. ■ Equipped with a dispensing device, allowing fully automated experiments (measurements) ■ Simultaneous measurement of 4 or 8 cells (continuous measurement of up to 48 cells) ■ 250 to 600 data points per day ■ Automation of gigaohm seal formation and whole-cell formation ■ Compatible with voltage-dependent and ligand-dependent channels ■ Measurement of action potentials using current clamp is also possible ■ Dynamic clamp capability (optional) ■ Temperature control and extracellular/intracellular perfusion possible ■ Cooling plate allows for cooling of cells and compounds ■ Borosilicate glass chips reduce compound adsorption ■ Comes with excellent analysis software
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Delivery Time
※Delivery times may vary depending on stock availability, so please feel free to contact us.
Applications/Examples of results
For more details, please refer to the PDF document or feel free to contact us. For inquiries about products, requests for demos, requests for catalogs, or any other inquiries, please feel free to contact us directly. Mail: info@nanion.jp
catalog（12）
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Company information
Nanion Technologies is a scientific instrument manufacturer founded in 2002 in Munich, Germany, specializing in the automation of electrophysiology experiments. We enable the automation of electrophysiology experiments, supporting not only ion channel research but also a wide range of membrane protein-related studies. We offer a broad product lineup, including our industry-leading automated patch clamp system, transporter activity measurement systems, artificial lipid bilayer experimental devices, liposome production devices, and impedance, extracellular potential, and contraction force measurement systems for iPS-derived cardiomyocytes. These systems have been adopted by many universities, pharmaceutical companies, and research institutions both domestically and internationally, and are highly regarded. For inquiries about our products, requests for introductions, demo requests, or catalog requests, please contact us or our authorized distributors. Additionally, feel free to consult us about visiting our Tokyo lab (Meguro Ward) to see the systems and experiments. Mail: info@nanion.jp