It is a hexapeptide and zinc complex ingredient that has retinol-like activity and is effective in reducing wrinkles and improving acne.
Zinnerine is a hexapeptide-2 conjugated with zinc. It has efficacy similar to retinol and is characterized by having equal or greater activity than retinol. In vitro: - Inhibition of hyperkeratosis - Sebum suppression (5α-reductase): over -60% - Inhibition of acne bacteria: approximately -50% - Anti-inflammatory effects - IL1α: -35% - IL-6: over -20% - IL-8: over -20% - Promotion of collagen production (COL1A1 gene expression): +40% In vivo: - Suppression of acne papules: -20% (2 weeks) - Pore contraction: -20% - Improvement of wrinkles: over -30%
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basic information
Contipro is a biotechnology company and a global manufacturer that has been producing active ingredients used in the pharmaceutical and cosmetics industries for nearly 30 years. We offer a range of products, including sodium hyaluronate and its derivatives produced by fermentation, as well as distinctive peptides and natural polysaccharides.
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Recommended blending amount: 0.01 – 1% Please use in cold process.
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Starting as an import trading company in 1927, we have been developing our business with many overseas suppliers and domestic customers over the years. Through our services of connecting the two together, Higuchi has become the well trusted "Japan distribution channel" for suppliers, and the "dependable vendor" who provides a stable supply of the latest high-valued overseas products to customers. Today, we conduct not only importing but also exporting businesses, trilateral trades, and overseas business investments as well. We have also expanded to local subsidiaries in the United States and China, to which we are able to effectively network overseas. Higuchi believes in the criticalness of providing a stable supply to customers, and we also place the highest priority on the coexistence with suppliers, to whom we can mutually develop together in a long-term perspective. Your support and consideration to our corporate philosophy would be much appreciated.